{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T13:00:28Z","timestamp":1759496428164},"reference-count":11,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,9,4]]},"abstract":"<jats:p>Tick-borne relapsing fever (TBRF) is endemic in discrete areas throughout the world; however, a domestic or imported case of relapsing fever has not been reported in Japan. Here, we report the first imported case. A previously healthy 20-year-old woman presented to our hospital on October 8, 2010, because of recurrent fever and lower leg pain. Before consultation, she had experienced four febrile episodes at 10\u201312-day intervals after returning from her stay in Uzbekistan from 1 to 8 September. Giemsa stain of peripheral blood showed <jats:italic>Borrelia<\/jats:italic> spirochetes. The spirochete was identified as <jats:italic>Borrelia persica<\/jats:italic> by sequencing of the amplicons of flaB using polymerase chain reaction and phylogenetic analysis. The patient was diagnosed with TBRF, and she completed a 10-day course of minocycline 100 mg twice daily. After treatment, her periodic fever subsided. Physicians should be aware of TBRF in patients with recurrent fever who have returned from TBRF-endemic countries, including areas of the former USSR.<\/jats:p>","DOI":"10.4269\/ajtmh.13-0187","type":"journal-article","created":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T04:56:02Z","timestamp":1373950562000},"page":"460-461","source":"Crossref","is-referenced-by-count":14,"title":["The First Case of Imported Relapsing Fever in Japan"],"prefix":"10.4269","volume":"89","author":[{"given":"Satoshi","family":"Kutsuna","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Kawabata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kei","family":"Kasahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ai","family":"Takano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiichi","family":"Mikasa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Clin Infect Dis","first-page":"897","article-title":"Ticks and tickborne bacterial diseases in humans: an emerging infectious threat","volume":"32","author":"Parola","year":"2001"},{"key":"R2","series-title":"Environ Microbiol Rep","first-page":"632","article-title":"Characterization of reptile-associated Borrelia sp. in the vector tick, Amblyomma geoemydae, and its association with Lyme disease and relapsing fever Borrelia spp","volume":"3","author":"Takano","year":"2011"},{"key":"R3","series-title":"Acta Trop","first-page":"189","article-title":"Detection of relapsing fever in human blood samples from Israel using PCR targeting the glycerophosphodiester phosphodiesterase (GlpQ) gene","volume":"98","author":"Halperin","year":"2006"},{"key":"R4","series-title":"Ann Soc Belg Med Trop","first-page":"357","article-title":"Single dose minocycline and doxycycline treatment of tick-borne relapsing fever. A double-blind clinical trial in Rwanda","volume":"63","author":"de Pierpont","year":"1983"},{"key":"R5","series-title":"Ann Soc Belg Med Trop","first-page":"335","article-title":"Relapsing fevers. A review","volume":"64","author":"Goubau","year":"1984"},{"key":"R6","series-title":"Clin Microbiol Infect","first-page":"407","article-title":"Relapsing fever borreliosis in Eurasia\u2013forgotten, but certainly not gone!","volume":"15","author":"Assous","year":"2009"},{"key":"R7","series-title":"Emerg Infect Dis","first-page":"1325","article-title":"Tickborne relapsing fever caused by Borrelia persica, Uzbekistan and Tajikistan","volume":"17","author":"Colin de Verdiere","year":"2011"},{"key":"R8","series-title":"Euro Surveill","first-page":"1468","article-title":"Imported cases of relapsing fever in Germany","volume":"4","author":"Twisselmann","year":"2000"},{"key":"R9","series-title":"Emerg Infect Dis","first-page":"1801","article-title":"Imported tickborne relapsing fever, France","volume":"11","author":"Wyplosz","year":"2005"},{"key":"R10","series-title":"J Clin Microbiol","first-page":"2027","article-title":"Tick-borne relapsing fever imported from West Africa: diagnosis by quantitative buffy coat analysis and in vitro culture of Borrelia crocidurae","volume":"37","author":"van Dam","year":"1999"},{"key":"R11","series-title":"Emerg Infect Dis","first-page":"697","article-title":"Meningoencephalitis complicating relapsing fever in traveler returning from Senegal","volume":"18","author":"Bottieau","year":"2012"}],"container-title":["The American Society of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/89\/3\/article-p460.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/89\/3\/article-p460.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/89\/3\/article-p460.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T18:25:08Z","timestamp":1723055108000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/89\/3\/article-p460.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,4]]},"references-count":11,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.13-0187","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"type":"print","value":"0002-9637"},{"type":"electronic","value":"1476-1645"}],"subject":[],"published":{"date-parts":[[2013,9,4]]}}}