{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T13:42:28Z","timestamp":1762004548233},"reference-count":42,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,10,9]]},"abstract":"<jats:p>In 2010, toxigenic <jats:italic>Vibrio cholerae<\/jats:italic> was newly introduced to Haiti. Because resources are limited, decision-makers need to understand the effect of different preventive interventions. We built a static model to estimate the potential number of cholera cases averted through improvements in coverage in water, sanitation and hygiene (WASH) (i.e., latrines, point-of-use chlorination, and piped water), oral cholera vaccine (OCV), or a combination of both. We allowed indirect effects and non-linear relationships between effect and population coverage. Because there are limited incidence data for endemic cholera in Haiti, we estimated the incidence of cholera over 20 years in Haiti by using data from Malawi. Over the next two decades, scalable WASH interventions could avert 57,949\u201378,567 cholera cases, OCV could avert 38,569\u201377,636 cases, and interventions that combined WASH and OCV could avert 71,586\u201388,974 cases. Rate of implementation is the most influential variable, and combined approaches maximized the effect.<\/jats:p>","DOI":"10.4269\/ajtmh.13-0201","type":"journal-article","created":{"date-parts":[[2013,10,9]],"date-time":"2013-10-09T02:18:18Z","timestamp":1381285098000},"page":"633-640","source":"Crossref","is-referenced-by-count":27,"title":["Modeling the Effect of Water, Sanitation, and Hygiene and Oral Cholera Vaccine Implementation in Haiti"],"prefix":"10.4269","volume":"89","author":[{"given":"Isaac Chun-Hai","family":"Fung","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David L.","family":"Fitter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebekah H.","family":"Borse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin 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Number of Reported Cholera Cases","author":"World Health Organization","key":"R25"},{"year":"2013","series-title":"The World Factbook. Malawi","author":"Central Intelligence Agency","key":"R26"},{"article-title":"Coverage-effectiveness curve: evaluating the impact of water, sanitation and hygiene interventions","year":"2013","author":"Fung","key":"R27"},{"key":"R28","series-title":"PLoS Med","first-page":"e336","article-title":"Controlling endemic cholera with oral vaccines","volume":"4","author":"Longini","year":"2007"},{"key":"R29","series-title":"PLoS Negl Trop Dis","first-page":"e1289","article-title":"Efficacy of a low-cost, inactivated whole-cell oral cholera vaccine: results from 3 years of follow-up of a randomized, controlled trial","volume":"5","author":"Sur","year":"2011"},{"key":"R30","series-title":"Lancet","first-page":"1694","article-title":"Efficacy and safety of a modified killed-whole-cell oral cholera vaccine in India: an interim analysis of a cluster-randomised, double-blind, placebo-controlled trial","volume":"374","author":"Sur","year":"2009"},{"year":"2003","series-title":"Time Effects. 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