{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T08:38:45Z","timestamp":1792658325807,"version":"4.5.0"},"reference-count":20,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,4,2]]},"abstract":"<jats:p>The cornerstone of schistosomiasis control is mass praziquantel treatment in high prevalence areas. Adults are an important target population, given increasing recognition of the burden of male and female genital schistosomiasis. However, use of weighing scales to calculate praziquantel dosing in rural areas can be challenging. For school-age children, the World Health Organization (WHO) has approved a dose pole to simplify praziquantel dosing based on height. We modified the pediatric dose pole by adding two height categories and incorporating a simple overweight\/obesity adjustment, for simplified mass treatment of adults in sub-Saharan Africa. Using the rural Zimbabwean Demographic and Health Survey data, we show that the modified dose pole with body mass index adjustment would result in &gt; 98% of adults receiving an acceptable dose (30\u201360 mg\/kg), with only 1.4% and 0.3% receiving an inadequate dose (&lt; 30 mg\/kg) or high dose (&gt; 60 mg\/kg), respectively. An adult dose pole may provide a more feasible alternative to weighing scales in community-based praziquantel treatment programs.<\/jats:p>","DOI":"10.4269\/ajtmh.13-0252","type":"journal-article","created":{"date-parts":[[2014,3,4]],"date-time":"2014-03-04T04:42:51Z","timestamp":1393908171000},"page":"634-637","source":"Crossref","is-referenced-by-count":13,"title":["Dosing of Praziquantel by Height in Sub-Saharan African Adults"],"prefix":"10.4269","volume":"90","author":[{"given":"Chiquita A.","family":"Palha De Sousa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracy","family":"Brigham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Chasekwa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mduduzi N. N.","family":"Mbuya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James M.","family":"Tielsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean H.","family":"Humphrey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Prendergast","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Preventive Chemotherapy in Human Helminthiasis","author":"World Health Organization","year":"2006"},{"key":"R2","series-title":"Trans R Soc Trop Med Hyg","first-page":"542","article-title":"Development and validation of a \u2018tablet pole\u2019 for the administration of praziquantel in sub-Saharan Africa","volume":"95","author":"Montresor","year":"2001"},{"key":"R3","series-title":"Trans R Soc Trop Med Hyg","first-page":"78","article-title":"The WHO dose pole for the administration of praziquantel is also accurate in non-African populations","volume":"99","author":"Montresor","year":"2005"},{"key":"R4","article-title":"Report of a meeting to review the results of studies on the treatment of schistosomiasis in preschool-age children","author":"World Health Organization","year":"2011"},{"key":"R5","series-title":"In Health","first-page":"95","article-title":"Treatment of schistosomiasis in African infants and preschool-aged children: downward extension and biometric optimization of the current praziquantel dose pole","volume":"4","author":"Sousa-Figueiredo","year":"2012"},{"key":"R6","series-title":"Am J Trop Med Hyg","first-page":"364","article-title":"Urogenital schistosomiasis in women of reproductive age in Tanzania's Lake Victoria region","volume":"84","author":"Downs","year":"2011"},{"key":"R7","series-title":"AIDS","first-page":"593","article-title":"Association between genital schistosomiasis and HIV in rural Zimbabwean women","volume":"20","author":"Kjetland","year":"2006"},{"key":"R8","series-title":"PLoS Negl Trop Dis","first-page":"e1396","article-title":"Examining the relationship between urogenital schistosomiasis and HIV infection","volume":"5","author":"Mbabazi","year":"2011"},{"key":"R9","series-title":"Report of the WHO Informal Consultation on the Use of Praziquantel during Pregnancy\/Lactation and Albendazole\/Mebendazole in Children under 24 Months","author":"World Health Organization","year":"2002"},{"key":"R10","series-title":"J Clin Epidemiol","first-page":"655","article-title":"Pictogram use was validated for estimating individual's body mass index","volume":"63","author":"Keshtkar","year":"2010"},{"key":"R11","series-title":"Res Publ Assoc Res Nerv Ment Dis","first-page":"115","article-title":"Use of the Danish Adoption Register for the study of obesity and thinness","volume":"60","author":"Stunkard","year":"1983"},{"key":"R12","series-title":"Schistosomiasis","author":"World Health Organization","year":"2012"},{"key":"R13","series-title":"Afr Health Sci","first-page":"367","article-title":"Prevalence of overweight and obesity in young adults in Uganda","volume":"10","author":"Baalwa","year":"2010"},{"key":"R14","series-title":"BMC Public Health","first-page":"365","article-title":"Prevalence of obesity and associated risk factors among adults in Kinondoni municipal district, Dar es Salaam Tanzania","volume":"11","author":"Shayo","year":"2011"},{"key":"R15","series-title":"Ethn Dis","first-page":"54","article-title":"Body image assessment: comparison of figure rating scales among urban Black women","volume":"12","author":"Patt","year":"2002"},{"key":"R16","series-title":"Breast Cancer Res Treat","first-page":"133","article-title":"Breast cancer risk among women with long-standing lactation and reproductive parameters at low risk level: a case-control study in northern Tanzania","volume":"142","author":"Jordan","year":"2013"},{"key":"R17","series-title":"Trans R Soc Trop Med Hyg","first-page":"1120","article-title":"Field testing of the WHO dose pole for administration of praziquantel in the treatment of opisthorchiasis in Lao PDR","volume":"101","author":"Strandgaard","year":"2007"},{"key":"R18","series-title":"Bull World Health Organ","first-page":"361","article-title":"Ivermectin dose assessment without weighing scales","volume":"71","author":"Alexander","year":"1993"},{"key":"R19","series-title":"Int J Obes Relat Metab Disord","first-page":"1517","article-title":"Relating body mass index to figural stimuli: population-based normative data for caucasians","volume":"25","author":"Bulik","year":"2001"},{"key":"R20","series-title":"Int J Obes (Lond)","first-page":"336","article-title":"BMI-based body size guides for women and men: development and validation of a novel pictorial method to assess weight-related concepts","volume":"32","author":"Harris","year":"2008"}],"container-title":["The American Society of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/90\/4\/article-p634.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/90\/4\/article-p634.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/90\/4\/article-p634.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T21:29:02Z","timestamp":1723066142000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/90\/4\/article-p634.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,2]]},"references-count":20,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.13-0252","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,2]]}}}