{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T07:55:38Z","timestamp":1793087738884,"version":"4.5.0"},"reference-count":77,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,8,6]]},"abstract":"<jats:p>We investigated the epidemiological and clinical features of cryptosporidiosis, the molecular characteristics of infecting species and serum antibody responses to three <jats:italic>Cryptosporidium<\/jats:italic>-specific antigens in human immunodeficiency virus (HIV)\/acquired immunodeficiency syndrome (AIDS) patients in Kenya. <jats:italic>Cryptosporidium<\/jats:italic> was the most prevalent enteric pathogen and was identified in 56 of 164 (34%) of HIV\/AIDS patients, including 25 of 70 (36%) with diarrhea and 31 of 94 (33%) without diarrhea. Diarrhea in patients exclusively infected with <jats:italic>Cryptosporidium<\/jats:italic> was significantly associated with the number of children per household, contact with animals, and water treatment. <jats:italic>Cryptosporidium hominis<\/jats:italic> was the most prevalent species and the most prevalent subtype family was Ib. Patients without diarrhea had significantly higher serum IgG levels to <jats:italic>Ch<\/jats:italic>gp15, <jats:italic>Ch<\/jats:italic>gp40 and <jats:italic>Cp<\/jats:italic>23, and higher fecal IgA levels to <jats:italic>Ch<\/jats:italic>gp15 and <jats:italic>Ch<\/jats:italic>gp40 than those with diarrhea suggesting that antibody responses to these antigens may be associated with protection from diarrhea and supporting further investigation of these antigens as vaccine candidates.<\/jats:p>","DOI":"10.4269\/ajtmh.13-0254","type":"journal-article","created":{"date-parts":[[2014,5,28]],"date-time":"2014-05-28T06:49:05Z","timestamp":1401259745000},"page":"319-328","source":"Crossref","is-referenced-by-count":52,"title":["Cryptosporidiosis in HIV\/AIDS Patients in Kenya: Clinical Features, Epidemiology, Molecular Characterization and Antibody Responses"],"prefix":"10.4269","volume":"91","author":[{"given":"Jane 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