{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T05:49:44Z","timestamp":1793684984320,"version":"4.5.1"},"reference-count":43,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,12,4]]},"abstract":"<jats:p>Using a novel analytical approach, weather dynamics and seasonal dengue virus transmission cycles were profiled for each Thailand province, 1983\u20132001, using monthly assessments of cases, temperature, humidity, and rainfall. We observed systematic differences in the structure of seasonal transmission cycles of different magnitude, the role of weather in regulating seasonal cycles, necessary versus optimal transmission \u201cweather-space,\u201d basis of large epidemics, and predictive indicators that estimate risk. Larger epidemics begin earlier, develop faster, and are predicted at <jats:italic>Onset change-point<\/jats:italic> when case counts are low. Temperature defines a viable range for transmission; humidity amplifies the potential within that range. This duality is central to transmission. Eighty percent of 1.2 million severe dengue cases occurred when mean temperature was 27\u201329.5\u00b0C and mean humidity was &gt; 75%. Interventions are most effective when applied early. Most cases occur near <jats:italic>Peak<\/jats:italic>, yet small reductions at <jats:italic>Onset<\/jats:italic> can substantially reduce epidemic magnitude. Monitoring the <jats:italic>Quiet-Phase<\/jats:italic> is fundamental in effectively targeting interventions pre-emptively.<\/jats:p>","DOI":"10.4269\/ajtmh.13-0321","type":"journal-article","created":{"date-parts":[[2013,8,20]],"date-time":"2013-08-20T00:24:18Z","timestamp":1376958258000},"page":"1066-1080","source":"Crossref","is-referenced-by-count":118,"title":["The Complex Relationship between Weather and Dengue Virus Transmission in Thailand"],"prefix":"10.4269","volume":"89","author":[{"given":"Karen M.","family":"Campbell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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