{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T04:03:23Z","timestamp":1768449803080,"version":"3.49.0"},"reference-count":34,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,5,7]]},"abstract":"<jats:p>We assessed the effect of mass azithromycin treatment on malaria parasitemia in a trachoma trial in Niger. Twenty-four study communities received treatment during the wet, high-transmission season. Twelve of the 24 communities were randomized to receive an additional treatment during the dry, low-transmission season. Outcome measurements were conducted at the community-level in children &lt; 1\u201372 months of age in May\u2013June 2011. Parasitemia was higher in the 12 once-treated communities (29.8%, 95% confidence interval [CI] = 21.5\u201340.0%) than in the 12 twice-treated communities (19.5%, 95% CI = 13.0\u201326.5%, <jats:italic>P<\/jats:italic> = 0.03). Parasite density was higher in once-treated communities (354 parasites\/\u03bcL, 95% CI = 117\u2013528 parasites\/\u03bcL) than in twice-treated communities (74 parasites\/\u03bcL, 95% CI = 41\u2013202 parasites\/\u03bcL, <jats:italic>P<\/jats:italic> = 0.03). Mass distribution of azithromycin reduced malaria parasitemia 4\u20135 months after the intervention. The results suggest that drugs with antimalaria activity can have long-lasting impacts on malaria during periods of low transmission.<\/jats:p>","DOI":"10.4269\/ajtmh.13-0379","type":"journal-article","created":{"date-parts":[[2014,3,11]],"date-time":"2014-03-11T03:17:37Z","timestamp":1394507857000},"page":"846-851","source":"Crossref","is-referenced-by-count":29,"title":["Impact of Mass Azithromycin Distribution on Malaria Parasitemia during the Low-Transmission Season in Niger: A Cluster-Randomized Trial"],"prefix":"10.4269","volume":"90","author":[{"given":"Bruce D.","family":"Gaynor","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdou","family":"Amza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boubacar","family":"Kadri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baido","family":"Nassirou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ousmane","family":"Lawan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laouali","family":"Maman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole E.","family":"Stoller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun 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