{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T10:32:57Z","timestamp":1766485977457},"reference-count":30,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,8,6]]},"abstract":"<jats:p>This study was designed to examine the height-for-age <jats:italic>z<\/jats:italic>-scores (HAZ), and the prevalence of intestinal inflammation, gastrointestinal infections with parasites, and enteroaggregative <jats:italic>Escherichia coli<\/jats:italic> (EAEC) in rural Panamanian children. Stool microscopy and polymerase chain reaction (PCR) testing for EAEC detected <jats:italic>Giardia lamblia<\/jats:italic> (32%, 32 of 100) and EAEC (13%, 11 of 87) in the study participants, respectively. Anthropometric analyses showed that those children who were &gt; 12 months of age had lower HAZ scores (mean of \u22121.449) than the reference population. As a group, the children in the study 1 to 5 years of age did not show recovery from the previously mentioned decline in terms of their HAZ. The HAZ means of the children infected with <jats:italic>G. lamblia<\/jats:italic>, EAEC, and <jats:italic>Ascaris lumbricoides<\/jats:italic> were \u22121.49, \u22121.67, and \u22122.11, respectively. Furthermore, the study participants with <jats:italic>A. lumbricoides<\/jats:italic> and EAEC infections in the presence of lactoferrin showed another decrease of 0.19 and 0.13, respectively, in their HAZ means.<\/jats:p>","DOI":"10.4269\/ajtmh.13-0438","type":"journal-article","created":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T14:09:52Z","timestamp":1404223792000},"page":"267-272","source":"Crossref","is-referenced-by-count":8,"title":["Enteric Parasites and Enteroaggregative Escherichia coli in Children from Ca\u00f1azas County, Veraguas Province, Panama"],"prefix":"10.4269","volume":"91","author":[{"given":"Elena","family":"Jim\u00e9nez Guti\u00e9rrez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa","family":"Pineda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose E.","family":"Calzada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard L.","family":"Guerrant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jones B.","family":"Lima Neto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Relana C.","family":"Pinkerton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azael","family":"Salda\u00f1a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Am J Public Health","first-page":"31","article-title":"Food, sanitation, and the socioeconomic determinants of child growth in Colombia","volume":"71","author":"Koopman","year":"1981"},{"key":"R2","series-title":"Br J Nutr","first-page":"441","article-title":"A quantitative study into the role of infection in determining nutritional status in Gambian village children","volume":"37","author":"Rowland","year":"1977"},{"key":"R3","series-title":"Trans R Soc Trop Med Hyg","first-page":"196","article-title":"Infection and its effect on the growth of young children: a comparison of The Gambia and Uganda","volume":"71","author":"Cole","year":"1977"},{"key":"R4","series-title":"Am J Clin Nutr","first-page":"1215","article-title":"Effect of infection on food intake and the nutritional state: perspectives as viewed from the village","volume":"30","author":"Mata","year":"1977"},{"key":"R5","series-title":"Am J Dis Child","first-page":"1296","article-title":"Acute morbidity and physical growth in rural Guatemalan children","volume":"129","author":"Martorell","year":"1975"},{"key":"R6","series-title":"Int J Epidemiol","first-page":"1457","article-title":"Early childhood diarrhea and helminthiases associate with long-term linear growth faltering","volume":"30","author":"Moore","year":"2001"},{"key":"R7","series-title":"Lancet","first-page":"564","article-title":"Effects of stunting, diarrheal disease, and parasitic infection during infancy on cognition in late childhood: a follow-up study","volume":"359","author":"Berkman","year":"2002"},{"key":"R8","series-title":"Am J Trop Med Hyg","first-page":"590","article-title":"Early childhood diarrhea is associated with diminished cognitive function 4 to 7 years later in children in a northeast Brazilian shantytown","volume":"66","author":"Niehaus","year":"2002"},{"key":"R9","series-title":"Nat Rev Microbiol","first-page":"123","article-title":"Pathogenic Escherichia coli","volume":"2","author":"Kaper","year":"2004"},{"key":"R10","series-title":"Emerg Infect Dis","first-page":"251","article-title":"Enteroaggregative Escherichia coli","volume":"4","author":"Nataro","year":"1998"},{"key":"R11","series-title":"FEMS Microbiol Lett","first-page":"12","article-title":"Pathogenesis of enteroaggregative Escherichia coli infection","volume":"254","author":"Harrington","year":"2006"},{"key":"R12","series-title":"J Infect Dis","first-page":"506","article-title":"Enteroaggregative Escherichia coli (EAEC) impairs growth while malnutrition worsens EAEC infection: a novel murine model of the infection malnutrition cycle","volume":"202","author":"Roche","year":"2010"},{"key":"R13","series-title":"J Infect Dis","first-page":"88","article-title":"Enteroaggregative Escherichia coli produce intestinal inflammation and growth impairment and cause interleukin-8 release from intestinal epithelial cells","volume":"177","author":"Steiner","year":"1998"},{"key":"R14","series-title":"Curr Opin Pharmacol","first-page":"559","article-title":"Current concepts in the evaluation, diagnosis and management of acute infectious diarrhea","volume":"5","author":"Gadewar","year":"2005"},{"key":"R15","series-title":"J Gastroenterol","first-page":"1309","article-title":"Fecal lactoferrin is a sensitive and specific marker in identifying intestinal inflammation","volume":"98","author":"Kane","year":"2003"},{"key":"R16","series-title":"Pediatr Infect Dis J","first-page":"486","article-title":"Fecal screening tests in the approach to acute infectious diarrhea: a scientific overview","volume":"15","author":"Huicho","year":"1996"},{"year":"2007","series-title":"Diagnostic Medical Parasitology","author":"Garcia","key":"R17"},{"key":"R18","series-title":"Diagnost Micro Infect Dis","first-page":"81","article-title":"The dispersin-encoding gene (aap) is not restricted to enteroaggregative Escherichia coli","volume":"65","author":"Monteiro","year":"2009"},{"key":"R19","series-title":"Diagn Microbiol Infect Dis","first-page":"13","article-title":"Genotyping of enteroaggregative Escherichia coli and identification of target genes for the detection of both typical and atypical strains","volume":"55","author":"Jenkins","year":"2006"},{"key":"R20","series-title":"Ann Trop Paediatr","first-page":"9","article-title":"Fecal lactoferrin as a predictor of positive fecal culture in south Indian children with acute diarrhea","volume":"23","author":"Venkataraman","year":"2003"},{"key":"R21","series-title":"Pediatr Infect Dis J","first-page":"644","article-title":"Fecal lactoferrin, fecal leukocytes and occult blood in the diagnostic approach to childhood invasive diarrhea","volume":"16","author":"Huicho","year":"1997"},{"key":"R22","series-title":"Bolet\u00edn Estad\u00edstico de Salud 2008","first-page":"58","author":"Ben\u00edtez","year":"2009"},{"key":"R23","series-title":"Am J Trop Med Hyg","first-page":"280","article-title":"Prediction of child health by household density and asset-based indices in impoverished indigenous villages in rural Panam\u00e1","volume":"86","author":"Halpenny","year":"2012"},{"key":"R24","first-page":"2","article-title":"Estado nutricional de ni\u00f1os y ni\u00f1as menores de cinco a\u00f1os"},{"key":"R25","series-title":"Pediatrics","first-page":"e473","article-title":"Worldwide timing of growth faltering: revisiting implications for interventions","volume":"125","author":"Victora","year":"2010"},{"key":"R26","series-title":"Afr J Food Sci","first-page":"679","article-title":"Persistent child malnutrition in Tanzania: risks associated with traditional complementary foods","volume":"4","author":"Muhimbula","year":"2010"},{"key":"R27","series-title":"Am J Epidemiol","first-page":"1129","article-title":"Childhood malnutrition and infection network. Diarrhea in early childhood: short-term association with weight and long-term association with length","volume":"178","author":"Richard","year":"2013"},{"key":"R28","series-title":"Nutr Rev","first-page":"487","article-title":"Malnutrition as an enteric infectious disease with long-term effects on child development","volume":"66","author":"Guerrant","year":"2008"},{"key":"R29","series-title":"PLoS ONE","first-page":"e77581","article-title":"High malnutrition rate in Venezuelan Yanomami compared to Warao Ameridians and Creoles: significant associations with intestinal parasites and anemia","volume":"8","author":"Verhagen","year":"2013"},{"key":"R30","series-title":"Anemia","article-title":"Prevalence and risk factors of anemia among children 6\u201359 months old in Haiti","author":"Ayoya","year":"2013"}],"container-title":["The American Society of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/91\/2\/article-p267.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/91\/2\/article-p267.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/91\/2\/article-p267.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T21:19:43Z","timestamp":1723065583000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/91\/2\/article-p267.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,6]]},"references-count":30,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.13-0438","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"type":"print","value":"0002-9637"},{"type":"electronic","value":"1476-1645"}],"subject":[],"published":{"date-parts":[[2014,8,6]]}}}