{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T22:10:06Z","timestamp":1723068606415},"reference-count":14,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,3,5]]},"abstract":"<jats:p>We investigated the clinical characteristics and serologic types of tsutsugamushi disease on the largest island of South Korea. There were 141 patients with tsutsugamushi disease at Jeju National University Hospital and Seogwipo Medical Center between November of 2003 and December of 2012. Median age of patients was 61 years, and 59% were women. The major clinical manifestations were fever (80.5%) and skin rash (55.7%), with eschars evident in 75.8% of the patients. Genotype analysis of <jats:italic>Orientia tsutsugamushi<\/jats:italic> was conducted in 33 specimens. The genotype was identified as Boryong type in 17 of 33 patients and Taguchi type in 15 of 33 patients. In our study, although the Taguchi genotype is rarely reported in the endemic area, it was common on Jeju Island. This genotype may be associated with mild and moderate forms of tsutsugamushi disease.<\/jats:p>","DOI":"10.4269\/ajtmh.13-0511","type":"journal-article","created":{"date-parts":[[2014,1,21]],"date-time":"2014-01-21T03:35:52Z","timestamp":1390275352000},"page":"507-510","source":"Crossref","is-referenced-by-count":4,"title":["Unusual Genotypic Distribution of Orientia tsutsugamushi Strains Causing Human Infections on Jeju Island"],"prefix":"10.4269","volume":"90","author":[{"given":"Jeong Rae","family":"Yoo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Taek","family":"Heo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young-Sang","family":"Koh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sohyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seok","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"issue":"(Suppl 3)","key":"R1","series-title":"Clin Infect Dis","first-page":"S203","article-title":"Scrub typhus: the geographic distribution of phenotypic and genotypic variants of Orientia tsutsugamushi","volume":"48","author":"Kelly","year":"2009"},{"key":"R2","series-title":"Microbes Infect","first-page":"11","article-title":"Orientia tsutsugamushi infection: overview and immune 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reaction","volume":"65","author":"Ree","year":"2001"},{"key":"R8","series-title":"J Korean Med Sci","first-page":"1315","article-title":"Phylogenetic analysis of the 56-kDa type-specific protein genes of Orientia tsutsugamushi in Central Korea","volume":"27","author":"Jeong","year":"2012"},{"key":"R9","series-title":"Am J Trop Med Hyg","first-page":"924","article-title":"Severity predictors in eschar-positive scrub typhus and role of serum osteopontin","volume":"85","author":"Park","year":"2011"},{"key":"R10","series-title":"Am J Trop Med Hyg","first-page":"250","article-title":"Phylogenetic analysis of the 56 kDa protein genes of Orientia tsutsugamushi in Southwest Area of Korea","volume":"84","author":"Lee","year":"2011"},{"key":"R11","series-title":"FEMS Microbiol Lett","first-page":"163","article-title":"Phylogenetic analysis of Orientia tsutsugamushi strains based on the sequence homologies of 56-kDa type-specific antigen 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Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/90\/3\/article-p507.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/90\/3\/article-p507.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/90\/3\/article-p507.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T21:31:03Z","timestamp":1723066263000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/90\/3\/article-p507.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,5]]},"references-count":14,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.13-0511","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"type":"print","value":"0002-9637"},{"type":"electronic","value":"1476-1645"}],"subject":[],"published":{"date-parts":[[2014,3,5]]}}}