{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T05:18:52Z","timestamp":1789881532210,"version":"4.0.1"},"reference-count":42,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,8,6]]},"abstract":"<jats:p>Our objective was to determine the seroprevalence of <jats:italic>Trypanosoma cruzi<\/jats:italic> infection among mothers and children in two rural Mayan communities in Yucatan, Mexico and examine sociodemographic characteristics and adverse reproductive outcomes associated with maternal infection. We performed household surveys in the communities of Sudzal and Teya. Mothers were interviewed, and blood samples were obtained to perform rapid tests and enzyme-linked immunosorbent assays (ELISAs). We surveyed 390 mothers and 685 children. The overall seroprevalence was 2.3% among mothers and 0.4% among children. In Sudzal, we found a seroprevalence of 4.4% among mothers and 0.7% in children. In Teya, we found a seroprevalence of 0.9% among mothers and 0.3% among children. Compared with uninfected mothers, seropositive mothers reported more stillbirths (relative risk = 4.7; 95% confidence interval = 2.1\u201310.4). <jats:italic>T. cruzi<\/jats:italic> infection is present in these communities, and infected children indicate active transmission. Seropositivity in mothers is associated with a history of adverse reproductive outcomes.<\/jats:p>","DOI":"10.4269\/ajtmh.13-0527","type":"journal-article","created":{"date-parts":[[2014,6,17]],"date-time":"2014-06-17T04:06:43Z","timestamp":1402978003000},"page":"348-353","source":"Crossref","is-referenced-by-count":33,"title":["Seroprevalence of Trypanosoma cruzi Among Mothers and Children in Rural Mayan Communities and Associated Reproductive Outcomes"],"prefix":"10.4269","volume":"91","author":[{"given":"Rubi","family":"Gamboa-Le\u00f3n","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Ramirez-Gonzalez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Freddy S.","family":"Pacheco-Tucuch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"O'Shea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn","family":"Rosecrans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Pippitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Dumonteil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Buekens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Trends Parasitol","first-page":"583","article-title":"The future of Chagas disease control","volume":"22","author":"Schofield","year":"2006"},{"key":"R2","series-title":"Lancet Infect Dis","first-page":"92","article-title":"Clinical and epidemiological aspects of Chagas disease","volume":"1","author":"Prata","year":"2001"},{"key":"R3","series-title":"Acta Trop","first-page":"55","article-title":"Congenital parasitic infections: a review","volume":"121","author":"Carlier","year":"2012"},{"key":"R4","series-title":"Trop Med Int Health","first-page":"293","article-title":"Congenital transmission of Trypanosoma cruzi: an operational outline for detecting and treating infected infants in north-western Argentina","volume":"5","author":"Blanco","year":"2000"},{"key":"R5","series-title":"Rev Inst Med Trop Sao Paulo","first-page":"260","article-title":"Importance of the study of the macerated fetus for the diagnosis of congenital Chagas' disease","volume":"14","author":"Bittencourt","year":"1972"},{"key":"R6","series-title":"Salud Publica Mex","first-page":"322","article-title":"Update on Chagas' disease in Mexico","volume":"42","author":"Dumonteil","year":"1999"},{"key":"R7","series-title":"Rev Biomed","first-page":"185","article-title":"La enfermedad de Chagas en el estado de Yucat\u00e1n. 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