{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T20:28:27Z","timestamp":1770150507371,"version":"3.49.0"},"reference-count":10,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,7,2]]},"abstract":"<jats:p>Mucosal leishmaniasis (ML) is a chronic form of tegumentary leishmaniasis, which causes destructive lesions of nasal, pharyngeal, and laryngeal mucosa. We describe a case of leishmaniasis reactivation with simultaneous cutaneous and mucosal forms in a renal transplanted patient with no history of prior leishmaniasis. Reactivation after renal transplantation was not reported in Brazil. A 67-year-old woman receiving prednisone 20 mg\/day, tacrolimus 1 mg\/day, and mycophenolic acid 360 mg\/day presented with nose edema with erythema and cutaneous lesions. Amastigotes were identified on biopsies and the polymerase chain reaction confirmed <jats:italic>Leishmania<\/jats:italic> (<jats:italic>Viannia<\/jats:italic>) <jats:italic>braziliensis<\/jats:italic>. The patient was treated with liposomal amphotericin B but died 3 weeks after as a result of bacterial septic shock. In conclusion, tegumentary leishmaniasis can reactivate with simultaneous cutaneous and mucosal forms in a renal transplanted patient during the immunosuppressant therapy.<\/jats:p>","DOI":"10.4269\/ajtmh.13-0578","type":"journal-article","created":{"date-parts":[[2014,4,15]],"date-time":"2014-04-15T04:20:10Z","timestamp":1397535610000},"page":"81-83","source":"Crossref","is-referenced-by-count":23,"title":["Reactivation of Mucosal and Cutaneous Leishmaniasis in a Renal Transplanted Patient"],"prefix":"10.4269","volume":"91","author":[{"given":"Felipe F.","family":"Tuon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovana Marina","family":"Bombonatto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eveline Roesler","family":"Battaglin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus Henrique","family":"Sakumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valdir Sabbaga","family":"Amato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raphael Abeg\u00e3o","family":"de Camargo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f4nio Carlos","family":"Nicodemo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Lancet Infect Dis","first-page":"581","article-title":"Cutaneous leishmaniasis","volume":"7","author":"Reithinger","year":"2007"},{"key":"R2","series-title":"Int J Dermatol","first-page":"628","article-title":"Cutaneous leishmaniasis reactivation 2 years after treatment caused by systemic corticosteroids \u2013 first report","volume":"46","author":"Tuon","year":"2007"},{"key":"R3","series-title":"Int J Dermatol","first-page":"846","article-title":"Leishmaniasis recidiva cutis in New World cutaneous leishmaniasis","volume":"37","author":"Oliveira-Neto","year":"1998"},{"key":"R4","series-title":"Lancet Infect Dis","first-page":"191","article-title":"Leishmaniasis among organ transplant recipients","volume":"8","author":"Antinori","year":"2008"},{"key":"R5","series-title":"Trop Med Int Health","first-page":"1134","article-title":"Endemic and opportunistic infections in Brazilian solid organ transplant recipients","volume":"16","author":"Batista","year":"2011"},{"key":"R6","series-title":"Clin Immunol","first-page":"442","article-title":"Local immunological factors associated with recurrence of mucosal leishmaniasis","volume":"128","author":"Tuon","year":"2008"},{"key":"R7","series-title":"Am J Trop Med Hyg","first-page":"266","article-title":"Treatment of mucosal leishmaniasis in Latin America: systematic review","volume":"77","author":"Amato","year":"2007"},{"key":"R8","series-title":"Int J Dermatol","first-page":"109","article-title":"Treatment of New World cutaneous leishmaniasis\u2013a systematic review with a meta-analysis","volume":"47","author":"Tuon","year":"2008"},{"key":"R9","series-title":"Clin Infect Dis","first-page":"311","article-title":"Treatment of mucosal leishmaniasis with a lipid formulation of amphotericin B","volume":"44","author":"Amato","year":"2007"},{"key":"R10","series-title":"Am J Trop Med Hyg","first-page":"818","article-title":"Can we use a lower dose of liposomal amphotericin B for the treatment of mucosal American leishmaniasis?","volume":"85","author":"Amato","year":"2011"}],"container-title":["The American Society of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/91\/1\/article-p81.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/91\/1\/article-p81.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/91\/1\/article-p81.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T21:21:30Z","timestamp":1723065690000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/91\/1\/article-p81.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,2]]},"references-count":10,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.13-0578","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,2]]}}}