{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T23:18:40Z","timestamp":1781306320066,"version":"3.54.1"},"reference-count":27,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,5,7]]},"abstract":"<jats:p><jats:italic>Strongyloides stercoralis<\/jats:italic> infection is being increasingly diagnosed out of endemic areas. The aim of this study is to evaluate the usefulness of <jats:italic>S. stercoralis<\/jats:italic> serology for the management of probable strongyloidiasis in patients presenting with eosinophilia. Overall, 147 patients were included, 89 (60.5%) patients had a positive <jats:italic>S. stercoralis<\/jats:italic> serology. <jats:italic>Strongyloides stercoralis<\/jats:italic> larvae were detected only in 15 (10.2%) patients. Twenty-eight patients had human immunodeficiency virus infection. Eighty patients received ivermectin 200 mcg\/Kg\/day for 2 days, and follow-up 6 months after treatment could be performed in 32 patients: 26 (81.3%) patients reached the response to treatment criteria (negative serology 6 months after treatment or when by enzyme-linked immunosorbent assay the optical density ratio of post-treatment to pre-treatment decreased to 0.6), and 11 (34.4%) patients fulfilled the cure criteria (negative serology 6 months after treatment). <jats:italic>Strongyloides stercoralis<\/jats:italic> serology is a useful diagnostic tool both in the diagnosis of probable strongyloidiasis and follow-up after treatment.<\/jats:p>","DOI":"10.4269\/ajtmh.13-0678","type":"journal-article","created":{"date-parts":[[2014,3,11]],"date-time":"2014-03-11T03:17:37Z","timestamp":1394507857000},"page":"830-834","source":"Crossref","is-referenced-by-count":53,"title":["Usefulness of Strongyloides stercoralis Serology in the Management of Patients with Eosinophilia"],"prefix":"10.4269","volume":"90","author":[{"given":"Fernando","family":"Salvador","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Sulleiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adri\u00e1n","family":"S\u00e1nchez-Montalv\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Mar\u00eda","family":"Saugar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esperanza","family":"Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Pahissa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Israel","family":"Molina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Clin Infect Dis","first-page":"913","article-title":"Spectrum of illness in international migrants seen at GeoSentinel clinics in 1997\u20132009, part 1: US-bound migrants evaluated by comprehensive protocol-based health assessment","volume":"56","author":"Barnett","year":"2013"},{"key":"R2","series-title":"Strongyloidiasis","author":"World Health Organization"},{"key":"R3","series-title":"Am J Trop Med Hyg","first-page":"1088","article-title":"High rate of Strongyloidosis infection, out of endemic area, in patients with eosinophilia and without risk of exogenous reinfections","volume":"82","author":"Repetto","year":"2010"},{"key":"R4","series-title":"Clin Microbiol Rev","first-page":"208","article-title":"Strongyloides stercoralis in the immunocompromised population","volume":"17","author":"Keiser","year":"2004"},{"key":"R5","series-title":"Clin Infect Dis","first-page":"1040","article-title":"Diagnosis of Strongyloides stercoralis infection","volume":"33","author":"Siddiqui","year":"2001"},{"key":"R6","series-title":"Diagn Microbiol Infect Dis","first-page":"19","article-title":"Application of enzyme immunoassay for postchemotherapy evaluation of human strongyloidiasis","volume":"18","author":"Kobayashi","year":"1994"},{"key":"R7","series-title":"Am J Trop Med Hyg","first-page":"788","article-title":"Short report: management of chronic strongyloidiasis in immigrants and refugees: is serologic testing useful?","volume":"80","author":"Biggs","year":"2009"},{"key":"R8","series-title":"J Clin Microbiol","first-page":"1716","article-title":"Evaluation of a rapid enzyme-linked immunosorbent assay for diagnosis of strongyloidiasis","volume":"48","author":"Bon","year":"2010"},{"key":"R9","series-title":"PLoS Negl Trop Dis","first-page":"e1044","article-title":"Efficacy and safety of single and double doses of Ivermectin versus 7-day high dose Albendazole for chronic strongyloidiasis","volume":"5","author":"Suputtamongkol","year":"2011"},{"key":"R10","series-title":"Enferm Infecc Microbiol Clin","first-page":"528","article-title":"Imported diseases by immigrants and travelers: results from the Cooperative Network for the study of Imported Diseases by Immigrants and Travelers + Redivi","volume":"30","author":"D\u00edaz-Men\u00e9ndez","year":"2012"},{"key":"R11","series-title":"Trans R Soc Trop Med Hyg","first-page":"465","article-title":"Strongyloides stercoralis, the hidden worm. Epidemiological and clinical characteristics of 70 cases diagnosed in the North Metropolitan Area of Barcelona, Spain, 2003\u20132012","volume":"107","author":"Valerio","year":"2013"},{"key":"R12","series-title":"J Clin Microbiol","first-page":"2569","article-title":"Patterns of detection of Strongyloides stercoralis in stool specimens: implications for diagnosis and clinical trials","volume":"34","author":"Dreyer","year":"1996"},{"key":"R13","series-title":"Am J Trop Med Hyg","first-page":"967","article-title":"Fluctuations of larval excretion in Strongyloides stercoralis infection","volume":"60","author":"Uparanukraw","year":"1999"},{"key":"R14","series-title":"Zentralbl Bakteriol Mikrobiol Hyg [A]","first-page":"616","article-title":"Improved diagnosis of Strongyloides stercoralis by seven consecutive stool specimens","volume":"263","author":"Nielsen","year":"1987"},{"key":"R15","series-title":"PLoS Negl Trop Dis","first-page":"e2002","article-title":"The laboratory diagnosis and follow-up of strongyloidiasis: a systematic review","volume":"7","author":"Requena-M\u00e9ndez","year":"2013"},{"key":"R16","series-title":"J Egypt Soc Parasitol","first-page":"491","article-title":"Efficacy of ELISA in diagnosis of strongyloidiasis among the immune-compromised patients","volume":"25","author":"Abdul-Fattah","year":"1995"},{"key":"R17","series-title":"Am J Trop Med Hyg","first-page":"1196","article-title":"Tropical diseases screening in immigrant patients with HIV infection in a European country","volume":"88","author":"Salvador","year":"2013"},{"key":"R18","series-title":"J Immigr Minor Health","first-page":"796","article-title":"Should we look for Strongyloides stercoralis in foreign-born HIV-infected persons?","volume":"15","author":"Llenas-Garc\u00eda","year":"2013"},{"key":"R19","series-title":"J Travel Med","first-page":"84","article-title":"Parasite-specific IgG response and peripheral blood eosinophil count following albendazole treatment for presumed chronic strongyloidiasis","volume":"13","author":"Karunajeewa","year":"2006"},{"key":"R20","series-title":"Trans R Soc Trop Med Hyg","first-page":"1056","article-title":"Utility of serological follow-up of chronic strongyloidiasis after anthelminthic chemotherapy","volume":"100","author":"Page","year":"2006"},{"key":"R21","series-title":"Trans R Soc Trop Med Hyg","first-page":"702","article-title":"Parasite-specific serum IgG following successful treatment of endemic strongyloidiasis using ivermectin","volume":"90","author":"Lindo","year":"1996"},{"key":"R22","series-title":"Am J Trop Med Hyg","first-page":"749","article-title":"Serology and eosinophil count in the diagnosis and management of strongyloidiasis in a non-endemic area","volume":"66","author":"Loutfy","year":"2002"},{"key":"R23","series-title":"PLoS Negl Trop Dis","first-page":"e1254","article-title":"Randomized clinical trial on ivermectin versus thiabendazole for the treatment of strongyloidiasis","volume":"5","author":"Bisoffi","year":"2011"},{"key":"R24","series-title":"Vaccine Immunol","first-page":"1624","article-title":"Improved diagnosis of Strongyloides stercoralis using recombinant antigen-based serologies in a community-wide study in Northern Argentina","volume":"17","author":"Krolewiecki","year":"2010"},{"key":"R25","series-title":"J Egypt Soc Parasitol","first-page":"757","article-title":"ELISA-based coproantigen in human strongyloidiasis: a diagnostic method correlating with worm burden","volume":"39","author":"El-Badry","year":"2009"},{"key":"R26","series-title":"J Med Microbiol","first-page":"454","article-title":"Novel real-time PCR for the universal detection of Strongyloides species","volume":"60","author":"Kramme","year":"2011"},{"key":"R27","series-title":"Trans R Soc Trop Med Hyg","first-page":"342","article-title":"Molecular diagnosis of Strongyloides stercoralis in fecal samples using real-time PCR","volume":"103","author":"Verweij","year":"2009"}],"container-title":["The American Society of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/90\/5\/article-p830.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/90\/5\/article-p830.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/90\/5\/article-p830.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T21:26:59Z","timestamp":1723066019000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/90\/5\/article-p830.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,7]]},"references-count":27,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.13-0678","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,7]]}}}