{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T06:44:27Z","timestamp":1774680267506,"version":"3.50.1"},"reference-count":16,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,4,2]]},"abstract":"<jats:p>Malaria infections in pregnancy are associated with adverse outcomes for both mother and child. There are few data on hyper-reactive malarial splenomegaly, an aberrant immunological response to chronic or recurrent malaria in pregnancy. This retrospective assessment reviewed the impact of mefloquine treatment on pregnant women with suspected hyper-reactive malarial splenomegaly in an area of low malaria transmission in the 1990s, showing significant reductions in spleen size and anemia and anti-malarial antibody titers without any notable negative effect on treated women or their newborns.<\/jats:p>","DOI":"10.4269\/ajtmh.13-0706","type":"journal-article","created":{"date-parts":[[2014,3,4]],"date-time":"2014-03-04T04:42:51Z","timestamp":1393908171000},"page":"609-611","source":"Crossref","is-referenced-by-count":8,"title":["Treatment of Suspected Hyper-Reactive Malarial Splenomegaly (HMS) in Pregnancy with Mefloquine"],"prefix":"10.4269","volume":"90","author":[{"given":"Juthamas","family":"Jaroensuk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Stoesser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mara L.","family":"Leimanis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Podjanee","family":"Jittamala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas J.","family":"White","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francois H.","family":"Nosten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rose","family":"McGready","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Lancet Infect Dis","first-page":"93","article-title":"Epidemiology and burden of malaria in pregnancy","volume":"7","author":"Desai","year":"2007"},{"key":"R2","series-title":"Lancet Infect Dis","first-page":"75","article-title":"Malaria in pregnancy in the Asia-Pacific region","volume":"12","author":"Rijken","year":"2013"},{"key":"R3","series-title":"Trans R Soc Trop Med Hyg","first-page":"100","article-title":"Chronic splenomegaly in Nairobi, Kenya. 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The role of rapid antigen-detecting and PCR-based tests","volume":"36","author":"Mothe","year":"2008"},{"key":"R16","series-title":"Arch Intern Med","first-page":"257","article-title":"Splenomegaly in Hmong refugees","volume":"144","author":"Paulson","year":"1984"}],"container-title":["The American Society of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/90\/4\/article-p609.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/90\/4\/article-p609.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/90\/4\/article-p609.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T21:29:53Z","timestamp":1723066193000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/90\/4\/article-p609.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,2]]},"references-count":16,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.13-0706","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,2]]}}}