{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T03:25:19Z","timestamp":1793071519226,"version":"4.5.0"},"reference-count":58,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,6,4]]},"abstract":"<jats:p>Parasitological diagnostic methods for schistosomiasis lack sensitivity, especially in regions of low endemicity. The objective of this study was to determine the prevalence of <jats:italic>Schistosoma mansoni<\/jats:italic> infections by antibody detection using the indirect immunofluorescence assay (IFA-IgM) and circumoval precipitin test (COPT). Serum samples of 572 individuals were randomly selected. The IFA-IgM and COPT were used to detect anti-<jats:italic>S. mansoni<\/jats:italic> antibodies. Of the patients studied, 15.9% (<jats:italic>N<\/jats:italic> = 91) were IFA-IgM positive and 5.1% (<jats:italic>N<\/jats:italic> = 29) had COPT reactions (<jats:italic>P<\/jats:italic> &lt; 0.001 by McNemar's test). Immunodiagnostic techniques showed higher infection prevalence than had been previously estimated. This study suggests that combined use of these diagnostic tools could be useful for the diagnosis of schistosomiasis in epidemiological studies in areas of low endemicity.<\/jats:p>","DOI":"10.4269\/ajtmh.13-0746","type":"journal-article","created":{"date-parts":[[2014,3,18]],"date-time":"2014-03-18T06:17:58Z","timestamp":1395123478000},"page":"1146-1152","source":"Crossref","is-referenced-by-count":14,"title":["Detection of Schistosoma mansoni Antibodies in a Low-Endemicity Area Using Indirect Immunofluorescence and Circumoval Precipitin Test"],"prefix":"10.4269","volume":"90","author":[{"given":"Maria Cristina","family":"Carvalho do Esp\u00edrito-Santo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Luiz","family":"Pinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cybele","family":"Gargioni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica Viviana","family":"Alvarado-Mora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera L\u00facia","family":"Pagliusi Castilho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Ranato Rebello","family":"Pinho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Expedito Jos\u00e9","family":"de Albuquerque Luna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronaldo Cesar","family":"Borges Gryschek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Prevention and Control of Schistosomiasis and the Soil-Transmitted Helminthiasis","first-page":"73","author":"World Health Organization","year":"2001"},{"key":"R2","series-title":"Acta Trop","first-page":"41","article-title":"The global status of schistosomiasis and its control","volume":"77","author":"Chitsulo","year":"2000"},{"key":"R3","series-title":"Report of Informal Consultation on Schistosomiasis in Low Transmission Areas: Control Strategies and Criteria for Elimination","first-page":"52","author":"World Health Organization","year":"2001"},{"key":"R4","series-title":"Mem Inst Oswaldo Cruz","first-page":"29","article-title":"Low transmission areas of schistosomiasis in Venezuela: consequences on the diagnosis, treatment, and control","volume":"101","author":"Alarc\u00f3n de Noya","year":"2006"},{"key":"R5","article-title":"Secretaria de Vigil\u00e2ncia a Sa\u00fade. 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