{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T12:44:56Z","timestamp":1784205896588,"version":"3.55.0"},"reference-count":26,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,10,1]]},"abstract":"<jats:p>Multiple <jats:italic>Vibrio cholerae<\/jats:italic> infections within the same household are common. Household contacts of patients with cholera were observed with daily clinical assessments and collection of rectal swab cultures for nine days after presentation of the index case. During the follow-up period, 71 (24%) of 294 household contacts developed a positive <jats:italic>V. cholerae<\/jats:italic> rectal swab, signifying bacterial shedding. The average length of bacterial shedding was 2.0 days (95% confidence interval 1.7\u20132.4). However, 16 (5%) of 294 contacts shed <jats:italic>V. cholerae<\/jats:italic> for \u2265 4 days. In a multivariate analysis, malnutrition was predictive of long-term shedding (odds ratio = 1.4, 95% confidence interval = 1.3\u201313, <jats:italic>P<\/jats:italic> = 0.02). High rates of <jats:italic>V. cholerae<\/jats:italic> infection and bacterial shedding among household contacts of cholera patients represent an opportunity for intervention to reduce <jats:italic>V. cholerae<\/jats:italic> transmission.<\/jats:p>","DOI":"10.4269\/ajtmh.14-0095","type":"journal-article","created":{"date-parts":[[2014,8,12]],"date-time":"2014-08-12T04:02:08Z","timestamp":1407816128000},"page":"738-742","source":"Crossref","is-referenced-by-count":49,"title":["Bacterial Shedding in Household Contacts of Cholera Patients in Dhaka, Bangladesh"],"prefix":"10.4269","volume":"91","author":[{"given":"Ana A.","family":"Weil","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmin","family":"Begum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahima","family":"Chowdhury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashraful I.","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel T.","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regina C.","family":"LaRocque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richelle C.","family":"Charles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward T.","family":"Ryan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen B.","family":"Calderwood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Firdausi","family":"Qadri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason B.","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Lancet Infect Dis","first-page":"521","article-title":"The true burden and risk of cholera: implications for prevention and control","volume":"7","author":"Zuckerman","year":"2007"},{"key":"R2","series-title":"Am J Trop Med Hyg","first-page":"12","article-title":"Mortality, morbidity, and microbiology of endemic cholera among hospitalized patients in Dhaka, 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