{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T16:59:44Z","timestamp":1770483584581,"version":"3.49.0"},"reference-count":51,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,12,3]]},"abstract":"<jats:p>Dengue is the most important mosquito-borne viral disease to humans. Bats are potential reservoirs for flaviviruses, including dengue virus (DENV). In this work, <jats:italic>Artibeus jamaicensis<\/jats:italic> bats were inoculated with two serotypes of DENV using different routes. For experimental inoculations (EI) 1 and 2, bats were inoculated subcutaneously or intraperitoneally with DENV-4; for EI-3 bats were inoculated intraperitoneally with DENV-1. Mock inoculated bats were kept as controls. In EI-4, bats were bitten by <jats:italic>Aedes aegypti<\/jats:italic> mosquitoes infected with DENV-1 or 4. Reverse transcription-polymerase chain reaction assays in plasma and spleen tissue collected from Day 1 to Days 9\u201317 after inoculation failed to reveal the presence of viral RNA in any of the samples. No evidence of circulating NS1 or specific anti-DENV IgG was detected in the plasma of the inoculated bats. These results indicate that <jats:italic>A. jamaicensis<\/jats:italic> bats are incapable of sustaining dengue virus replication and are unlikely to act as reservoirs for this virus.<\/jats:p>","DOI":"10.4269\/ajtmh.14-0361","type":"journal-article","created":{"date-parts":[[2014,10,14]],"date-time":"2014-10-14T03:10:13Z","timestamp":1413256213000},"page":"1227-1234","source":"Crossref","is-referenced-by-count":36,"title":["Experimental Inoculation of Artibeus jamaicensis Bats with Dengue Virus Serotypes 1 or 4 Showed No Evidence of Sustained Replication"],"prefix":"10.4269","volume":"91","author":[{"given":"Salom\u00e9","family":"Cabrera-Romo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benito","family":"Recio-T\u00f3toro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana 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