{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T16:47:49Z","timestamp":1780418869773,"version":"3.54.1"},"reference-count":21,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,1,7]]},"abstract":"<jats:p>Yaws, a non-venereal treponemal disease, is targeted for eradication by 2020 but accurate epidemiological data to guide control programs remain sparse. The Solomon Islands reports the second highest number of cases of yaws worldwide. We conducted a cluster randomized survey of yaws in two provinces of the Solomon Islands. One thousand four hundred and ninety-seven (1,497) children 5\u201314 years of age were examined. Clinical signs of active yaws were found in 79 children (5.5%), whereas 140 children (9.4%) had evidence of healed yaws lesions. Four hundred and seventy (470) (31.4%) children had a positive <jats:italic>Treponema pallidum<\/jats:italic> particle agglutination assay (TPPA). Two hundred and eighty-five (285) children (19%) had a positive TPPA and rapid plasma regain assay. Risk of yaws increased with age and was more common in males. The prevalence of yaws at village level was the major risk factor for infection. Our findings suggest the village, not the household, should be the unit of treatment in the World Health Organization (WHO) yaws eradication strategy.<\/jats:p>","DOI":"10.4269\/ajtmh.14-0438","type":"journal-article","created":{"date-parts":[[2014,11,25]],"date-time":"2014-11-25T04:31:09Z","timestamp":1416889869000},"page":"129-133","source":"Crossref","is-referenced-by-count":35,"title":["Mapping the Epidemiology of Yaws in the Solomon Islands: A Cluster Randomized Survey"],"prefix":"10.4269","volume":"92","author":[{"given":"Michael","family":"Marks","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ventis","family":"Vahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Sokana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elliot","family":"Puiahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Pavluck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaixing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tenneth","family":"Dalipanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Bottomley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Mabey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony W.","family":"Solomon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"R1","series-title":"BMJ","first-page":"1280","article-title":"On the presence of spirochaetes in two cases of ulcerated parangi (Yaws)","volume":"2","author":"Castellani","year":"1905"},{"key":"R2","series-title":"PLoS Negl Trop Dis","first-page":"e1471","article-title":"Whole genome sequences of three Treponema pallidum ssp. pertenue strains: yaws and syphilis treponemes differ in less than 0.2% of the genome sequence","volume":"6","author":"Cejkov\u00e1","year":"2012"},{"key":"R3","series-title":"Handbook of Endemic Treponematoses : Yaws, Endemic Syphilis and Pinta","author":"Perine","year":"1984"},{"key":"R4","series-title":"Bull World Health Organ","first-page":"127","article-title":"Extent and nature of the yaws problem in Africa","volume":"8","author":"Hackett","year":"1953"},{"key":"R5","series-title":"Lancet","first-page":"763","article-title":"Yaws","volume":"381","author":"Mitj\u00e0","year":"2013"},{"key":"R6","series-title":"P N G Med J","first-page":"247","article-title":"Resurgent yaws and other skin diseases in the Western Province of the Solomon Islands","volume":"28","author":"Eason","year":"1985"},{"key":"R7","series-title":"P N G Med J","first-page":"206","article-title":"Yaws in the periurban settlements of Port Moresby, Papua New Guinea","volume":"45","author":"Manning","year":"2002"},{"key":"R8","series-title":"Trop Doct","first-page":"68","article-title":"Resurgence of yaws in Tanna, Vanuatu: time for a new approach?","volume":"40","author":"Fegan","year":"2010"},{"key":"R9","series-title":"PLoS ONE","first-page":"e6338","article-title":"Prevalence study of yaws in the Democratic Republic of Congo using the lot quality assurance sampling method","volume":"4","author":"Gerstl","year":"2009"},{"key":"R10","series-title":"BMC Res Notes","first-page":"543","article-title":"Clinical outcome of skin yaws lesions after treatment with benzathine benzylpenicillin in a pygmy population in Lobaye, Central African Republic","volume":"4","author":"Manirakiza","year":"2011"},{"key":"R11","series-title":"Lancet","first-page":"342","article-title":"Single-dose azithromycin versus benzathine benzylpenicillin for treatment of yaws in children in Papua New Guinea: an open-label, non-inferiority, randomized trial","volume":"379","author":"Mitj\u00e0","year":"2012"},{"key":"R12","series-title":"Wkly Epidemiol Rec","first-page":"189","article-title":"Eradication of yaws: the Morges Strategy","volume":"87","author":"The World Health Organization","year":"2012"},{"key":"R13","series-title":"Genitourin Med","first-page":"343","article-title":"Yaws in Ecuador: impact of control measures on the disease in the Province of Esmeraldas","volume":"71","author":"Anselmi","year":"1995"},{"key":"R14","article-title":"Completing the Baseline Map of the Preventive-Chemotherapy Neglected Tropical Diseases (NTDs): The Global Trachoma Mapping Project and WHO's NTD Mapping Initiative","author":"Kabore","year":"2013"},{"key":"R15","series-title":"PLoS Negl Trop Dis","first-page":"e2654","article-title":"Electronic data capture tools for global health programs: evolution of LINKS, an android-, web-based system","volume":"8","author":"Pavluck","year":"2014"},{"key":"R16","series-title":"Emerg Infect Dis","first-page":"1083","article-title":"Outcome predictors in treatment of yaws","volume":"17","author":"Mitj\u00e0","year":"2011"},{"key":"R17","series-title":"J Trop Med Hyg","first-page":"52","article-title":"Yaws in the Solomon Islands","volume":"93","author":"Fegan","year":"1990"},{"key":"R18","series-title":"Australas J Dermatol","first-page":"98","article-title":"Cutaneous chancroid in a visitor from Vanuatu","volume":"49","author":"McBride","year":"2008"},{"key":"R19","series-title":"Lancet Glob Health","first-page":"e235","article-title":"Haemophilus ducreyi as a cause of skin ulcers in children from a yaws-endemic area of Papua New Guinea: a prospective cohort study","volume":"2","author":"Mitj\u00e0","year":"2014"},{"key":"R20","series-title":"Emerg Infect Dis","article-title":"Haemophilus ducreyi associated with skin ulcers among children, Solomon Islands","author":"Marks","year":"2014"},{"key":"R21","series-title":"Infect Immun","first-page":"3219","article-title":"Treponema pallidum subsp. pertenue displays pathogenic properties different from those of T. pallidum subsp. pallidum","volume":"68","author":"Wicher","year":"2000"}],"container-title":["The American Society of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/92\/1\/article-p129.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/92\/1\/article-p129.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/92\/1\/article-p129.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T19:32:28Z","timestamp":1723059148000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/92\/1\/article-p129.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,7]]},"references-count":21,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.14-0438","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,7]]}}}