{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T09:42:40Z","timestamp":1784194960738,"version":"3.55.0"},"reference-count":25,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,6,3]]},"abstract":"<jats:p>Histoplasmosis is a common endemic human mycoses acquired mostly in the Americas. We reviewed 23 cases of histoplasmosis in Israeli travelers; 22 had traveled to Central or South America and one to North America. Fourteen cases had been exposed to bat habitats and were symptomatic, presenting \u2264 3 months after their return. Asymptomatic patients (<jats:italic>N<\/jats:italic> = 9) were diagnosed during the evaluation of incidental radiological findings or because a travel partner had been suspected of <jats:italic>Histoplasma<\/jats:italic> infection, 16\u2013120 months after their return. Serological testing was positive in 75% of symptomatic cases but only 22% of asymptomatic cases. Histoplasmosis should be considered in travelers returning from the Americas with respiratory or febrile illness within weeks of return, particularly if exposed to bat habitats. Travel history is essential in patients presenting with pulmonary nodules, even years after travel to endemic countries.<\/jats:p>","DOI":"10.4269\/ajtmh.14-0509","type":"journal-article","created":{"date-parts":[[2015,4,28]],"date-time":"2015-04-28T02:21:46Z","timestamp":1430187706000},"page":"1168-1172","source":"Crossref","is-referenced-by-count":14,"title":["Histoplasmosis in Israeli Travelers"],"prefix":"10.4269","volume":"92","author":[{"given":"Michael J.","family":"Segel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Rozenman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark D.","family":"Lindsley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamar","family":"Lachish","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neville","family":"Berkman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ami","family":"Neuberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Clin Microbiol Rev","first-page":"115","article-title":"Histoplasmosis: a clinical and laboratory update","volume":"20","author":"Kauffman","year":"2007"},{"key":"R2","series-title":"Mycoses","first-page":"274","article-title":"Histoplasmosis: a review for clinicians from non-endemic areas","volume":"49","author":"Wheat","year":"2006"},{"key":"R3","series-title":"Medicine (Baltimore)","first-page":"339","article-title":"Histoplasmosis. Experience during outbreaks in Indianapolis and review of the literature","volume":"76","author":"Wheat","year":"1997"},{"key":"R4","series-title":"Clin Infect Dis","first-page":"1088","article-title":"Fungal infections among returning travelers","volume":"35","author":"Panackal","year":"2002"},{"key":"R5","series-title":"Am J Trop Med Hyg","first-page":"663","article-title":"A large outbreak of histoplasmosis among American travelers associated with a hotel in Acapulco, Mexico, Spring 2001","volume":"69","author":"Morgan","year":"2003"},{"key":"R6","series-title":"Eur J Clin Microbiol Infect Dis","first-page":"839","article-title":"Histoplasmosis infection in Spanish travelers to Latin America","volume":"24","author":"Gascon","year":"2005"},{"key":"R7","series-title":"Ann Intern Med","first-page":"456","article-title":"GeoSentinel surveillance of illness in returned travelers, 2007\u20132011","volume":"158","author":"Leder","year":"2013"},{"key":"R8","series-title":"J Travel Med","first-page":"258","article-title":"Imported histoplasmosis: two distinct profiles in travelers and immigrants","volume":"16","author":"Norman","year":"2009"},{"key":"R9","series-title":"J Infect Chemother","first-page":"107","article-title":"Imported mycoses: an update","volume":"9","author":"Miyaji","year":"2003"},{"key":"R10","series-title":"Rev Iberoam Micol","first-page":"169","article-title":"Imported and autochthonous histoplasmosis in Italy: new cases and old problems","volume":"22","author":"Farina","year":"2005"},{"key":"R11","series-title":"J Travel Med","first-page":"83","article-title":"A multinational outbreak of histoplasmosis following a biology field trip in the Ugandan rainforest","volume":"20","author":"Cottle","year":"2013"},{"key":"R12","series-title":"Am J Trop Med Hyg","first-page":"140","article-title":"Occurrence of Histoplasma capsulatum Darling, 1906 in Israel, with a review of the current status of histoplasmosis in the Middle East","volume":"26","author":"Ajello","year":"1977"},{"key":"R13","series-title":"Trans R Soc Trop Med Hyg","first-page":"504","article-title":"Histoplasmosis among hospitalized febrile patients in northern Tanzania","volume":"106","author":"Lofgren","year":"2012"},{"key":"R14","series-title":"J Assoc Physicians India","first-page":"25","article-title":"Histoplasmosis in India: truly uncommon or uncommonly recognised?","volume":"60","author":"Gopalakrishnan","year":"2012"},{"key":"R15","series-title":"J Assoc Physicians India","first-page":"185","article-title":"Disseminated histoplasmosis","volume":"53","author":"Subramanian","year":"2005"},{"key":"R16","series-title":"Medicine (Baltimore)","first-page":"61","article-title":"Histoplasmosis in Australia: report of 16 cases and literature review","volume":"90","author":"McLeod","year":"2011"},{"key":"R17","series-title":"Acta Clin Belg","first-page":"102","article-title":"Chronic disseminated histoplasmosis in an apparently immuno-competent Belgian patient","volume":"59","author":"Mahvi","year":"2004"},{"key":"R18","series-title":"J Travel Med","first-page":"176","article-title":"Acute histoplasmosis in spelunkers returning from Mato Grosso, Peru","volume":"4","author":"Nasta","year":"1997"},{"key":"R19","series-title":"Am J Trop Med Hyg","first-page":"438","article-title":"Histoplasmosis associated with exploring a bat-inhabited cave in Costa Rica, 1998\u20131999","volume":"70","author":"Lyon","year":"2004"},{"key":"R20","series-title":"MMWR","first-page":"1349","article-title":"Outbreak of histoplasmosis among travelers returning from El Salvador\u2013Pennsylvania and Virginia, 2008","volume":"57","author":"CDC","year":"2008"},{"key":"R21","series-title":"Tropical Diseases in Travelers","first-page":"282","article-title":"Histoplasmosis and other endemic fungal infections","author":"Segel","year":"2010"},{"key":"R22","series-title":"JAMA","first-page":"109","article-title":"Serologic evidence of histoplasmosis in sanatoriums in the U.S","volume":"180","author":"Furcolow","year":"1962"},{"key":"R23","series-title":"Trends Microbiol","first-page":"488","article-title":"Current diagnosis of histoplasmosis","volume":"11","author":"Wheat","year":"2003"},{"key":"R24","series-title":"Am J Trop Med Hyg","first-page":"643","article-title":"Skin sensitivity to histoplasmin and coccidiodin in Israel","volume":"14","author":"Baum","year":"1965"},{"key":"R25","series-title":"Am J Trop Med Hyg","first-page":"643","article-title":"A skin test survey for histoplasmosis and coccidioidomycosis in the Middle East","volume":"7","author":"Daoud","year":"1958"}],"container-title":["The American Society of Tropical Medicine and 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