{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T05:54:39Z","timestamp":1789192479435,"version":"build-2803163510"},"reference-count":66,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,4,1]]},"abstract":"<jats:p>Migrants from developing countries are usually young and healthy but several studies report they may harbor asymptomatic infections for prolonged periods. Prevalence of infections were determined for asymptomatic immigrants from Latin America and sub-Saharan Africa who ettended to a European Tropical Medicine Referral Center from 2000 to 2009. A systematic screening protocol for selected infections was used. Data from 317 sub-Saharan Africans and 383 Latin Americans were analyzed. Patients were mostly young (mean age 29 years); there were significantly more males among sub-Saharan Africans (83% versus 31.6%) and pre-consultation period was longer for Latin Americans (5 versus 42 months). Diagnoses of human immunodeficiency virus (HIV), chronic hepatitis B and C virus infection, and latent tuberculosis were significantly more frequent in sub-Saharan Africans (2.3% versus 0.3%; 14% versus 1.6%; 1.3 versus 0%; 71% versus 32.1%). There were no significant differences in prevalence for syphilis and intestinal parasites. Malaria and schistosomiasis prevalence in sub-Saharan Africans was 4.6% and 5.9%, respectively, and prevalence of Chagas disease in Latin Americans was 48.5%. Identifying and treating asymptomatic imported infectious diseases may have an impact both for the individual concerned and for public health. Based on these results, a systematic screening protocol for asymptomatic immigrants is proposed.<\/jats:p>","DOI":"10.4269\/ajtmh.14-0520","type":"journal-article","created":{"date-parts":[[2015,2,3]],"date-time":"2015-02-03T02:58:31Z","timestamp":1422932311000},"page":"848-856","source":"Crossref","is-referenced-by-count":67,"title":["Screening of Imported Infectious Diseases Among Asymptomatic Sub-Saharan African and Latin American Immigrants: A Public Health Challenge"],"prefix":"10.4269","volume":"92","author":[{"given":"Bego\u00f1a","family":"Monge-Maillo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rogelio","family":"L\u00f3pez-V\u00e9lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca F.","family":"Norman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Ferrere-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1ngela","family":"Mart\u00ednez-P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Antonio","family":"P\u00e9rez-Molina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"R1","series-title":"World Migration Report: Migrant Well-Being and Development","doi-asserted-by":"crossref","DOI":"10.18356\/a981b1e5-en","author":"International Organization for Migration","year":"2013"},{"key":"R2","series-title":"MPI Data Hub: Migration, Facts, Stats and Maps","author":"Migration Policy Institute (MPI)","year":"2013"},{"key":"R3","series-title":"Municipal Register of Inhabitants (January 1, 2014)","author":"National Institute for Statistics","year":"2014"},{"key":"R4","series-title":"Public Health Rep","first-page":"69","article-title":"Prevalence of tuberculosis, hepatitis B virus, and intestinal parasitic infections among refugees to Minnesota","volume":"117","author":"Lifson","year":"2002"},{"key":"R5","series-title":"Emerg Infect Dis","first-page":"1745","article-title":"Imported infectious diseases in mobile populations, Spain","volume":"15","author":"Monge-Maillo","year":"2009"},{"key":"R6","series-title":"Trop Med Int Health","first-page":"223","article-title":"Mortality from infectious diseases among refugees and immigrants compared to native Danes: a historical prospective cohort study","volume":"17","author":"Norredam","year":"2011"},{"key":"R7","series-title":"J Travel Med","first-page":"145","article-title":"Illness in returned travelers and immigrants\/refugees: the 6-year experience of two Australian infectious diseases units","volume":"13","author":"O'Brien","year":"2006"},{"key":"R8","series-title":"Euro Surveill","first-page":"E070906.1","article-title":"An outbreak of chikungunya fever in the province of Ravenna, Italy","volume":"12","author":"Angelini","year":"2007"},{"key":"R9","series-title":"Emerg Infect Dis","first-page":"784","article-title":"Mapping environmental suitability for malaria transmission, Greece","volume":"19","author":"Sudre","year":"2013"},{"key":"R10","series-title":"Enferm Infecc Microbiol Clin","first-page":"654","article-title":"Changes in the epidemiology of tuberculosis: the influence of international migration flows","volume":"29","author":"Fortun","year":"2011"},{"key":"R11","series-title":"Prim Care","first-page":"879","article-title":"Screening of international immigrants, refugees, and adoptees","volume":"29","author":"Stauffer","year":"2002"},{"key":"R12","series-title":"Travel Med Infect Dis","first-page":"4","article-title":"Communicable diseases in the immigrant population attended to in a tropical medicine unit: epidemiological aspects and public health issues","volume":"6","author":"Manzardo","year":"2008"},{"key":"R13","series-title":"Enferm Infecc Microbiol Clin","first-page":"535","article-title":"Recommendations for the diagnosis, treatment and follow-up of the pregnant woman and child with chagas disease","volume":"31","author":"Gonzalez-Tome","year":"2013"},{"key":"R14","article-title":"Sistemas auton\u00f3micos de vigilancia epidemiol\u00f3gica. Centro Nacional de Epidemiolog\u00eda. Vigilancia epidemiol\u00f3gica del VIH\/SIDA en Espa\u00f1a junio","author":"de Sanidad","year":"2013"},{"key":"R15","article-title":"Jefatura de estado. Real Decreto -Ley 16\/2012, 20 de abril, de medidas urgentes para garantizar la sostenibilidad del sistema nacional de salud y mejorar la calidad y seguridad de sus prestaciones"},{"key":"R16","series-title":"MMWR Recomm Rep","first-page":"1","article-title":"Revised recommendations for HIV testing of adults, adolescents, and pregnant women in health-care settings","volume":"55","author":"Branson","year":"2006"},{"key":"R17","series-title":"J Antimicrob Chemother","first-page":"312","article-title":"Very late initiation of HAART impairs treatment response at 48 and 96 weeks: results from a meta-analysis of randomized clinical trials","volume":"67","author":"Perez-Molina","year":"2012"},{"key":"R18","series-title":"AASLD Practice Guidelines Update. Chronic Hepatitis B: Update","author":"American Association for the Study of Liver Disease (AASLD)","year":"2009"},{"key":"R19","series-title":"CMAJ","first-page":"E824","article-title":"Evidence-based clinical guidelines for immigrants and refugees","volume":"183","author":"Pottie","year":"2011"},{"key":"R20","series-title":"Clin Infect Dis","first-page":"1294","article-title":"The cost-effectiveness of screening for chronic hepatitis B infection in the United States","volume":"52","author":"Eckman","year":"2011"},{"key":"R21","series-title":"Enferm Infecc Microbiol Clin","first-page":"121","article-title":"Hepatitis B virus (HBV) infection in sub-Saharan immigrants in Almeria (Spain)","volume":"29","author":"Salas","year":"2011"},{"key":"R22","series-title":"J Viral Hepat","first-page":"294","article-title":"Clinical, epidemiological characteristics and indications for liver biopsy and treatment in immigrants with chronic hepatitis B at a referral hospital in Madrid","volume":"18","author":"Perez-Molina","year":"2011"},{"key":"R23","series-title":"J Med Virol","first-page":"1565","article-title":"Isolated core antibody hepatitis B in sub-Saharan African immigrants","volume":"80","author":"Gibney","year":"2008"},{"key":"R24","series-title":"Hepatology","first-page":"1335","article-title":"Diagnosis, management, and treatment of hepatitis C: an update","volume":"49","author":"Ghany","year":"2009"},{"key":"R25","series-title":"Dig Liver Dis","first-page":"589","article-title":"Recommendations for the prevention, diagnosis, and treatment of chronic hepatitis B and C in special population groups (migrants, intravenous drug users and prison inmates)","volume":"43","author":"Almasio","year":"2011"},{"key":"R26","series-title":"Gac Sanit","first-page":"288","article-title":"Indication of determination of antibodies against hepatitis C and A viruses in the protocol for the care of young immigrants","volume":"24","author":"Masvidal Aliberch","year":"2010"},{"key":"R27","series-title":"JAMA","first-page":"1510","article-title":"Update on syphilis: resurgence of an old problem","volume":"290","author":"Golden","year":"2003"},{"key":"R28","series-title":"Lancet Infect Dis","first-page":"684","article-title":"Effectiveness of interventions to improve screening for syphilis in pregnancy: a systematic review and meta-analysis","volume":"11","author":"Hawkes","year":"2011"},{"key":"R29","series-title":"Aten Primaria","first-page":"84","article-title":"Comparative analysis of serological tests performed in immigrants in the Lleida health area","volume":"45","author":"Soler-Gonzalez","year":"2013"},{"key":"R30","series-title":"MMWR Recomm Rep","first-page":"1","article-title":"Screening for tuberculosis in high-risk populations: recommendations of the Advisory Committee for Elimination of Tuberculosis","volume":"39","author":"Center for Disease Control and Prevention (CDC)","year":"1990"},{"key":"R31","series-title":"Eur Respir J","first-page":"1107","article-title":"Cost-effectiveness of tuberculosis control strategies among immigrants and refugees","volume":"25","author":"Dasgupta","year":"2005"},{"key":"R32","series-title":"N Engl J Med","first-page":"1850","article-title":"Global drug-resistance patterns and the management of latent tuberculosis infection in immigrants to the United States","volume":"347","author":"Khan","year":"2002"},{"key":"R33","series-title":"JAMA","first-page":"405","article-title":"Tuberculosis among foreign-born persons in the United States","volume":"300","author":"Cain","year":"2008"},{"key":"R34","series-title":"Am J Respir Crit Care Med","first-page":"S221","article-title":"Targeted tuberculin testing and treatment of latent tuberculosis infection. 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(IDSA), September 1999, and the sections of this statement","volume":"161"},{"key":"R35","series-title":"Int J Tuberc Lung Dis","first-page":"645","article-title":"The impact of immigration on tuberculosis rates in the United Kingdom compared with other European countries","volume":"13","author":"Gilbert","year":"2009"},{"key":"R36","series-title":"N Engl J Med","first-page":"2060","article-title":"Priorities for the treatment of latent tuberculosis infection in the united states","volume":"350","author":"Horsburgh","year":"2004"},{"key":"R37","series-title":"Clin Infect Dis","first-page":"826","article-title":"Treatment of latent tuberculosis infection in patients aged > or = 35 years","volume":"31","author":"Gilroy","year":"2000"},{"key":"R38","series-title":"Lancet Infect Dis","first-page":"435","article-title":"Screening of immigrants in the UK for imported latent tuberculosis: a multicentre cohort study and cost-effectiveness 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States","volume":"7","author":"Weissman","year":"1994"},{"key":"R43","series-title":"Am J Trop Med Hyg","first-page":"386","article-title":"Risk of intestinal helminth and protozoan infection in a refugee population","volume":"73","author":"Garg","year":"2005"},{"key":"R44","series-title":"Euro Surveill","first-page":"19973","article-title":"Targeted screening and health education for Chagas disease tailored to at-risk migrants in Spain, 2007 to 2010","volume":"16","author":"Navarro","year":"2011"},{"key":"R45","series-title":"Clin Microbiol Infect","first-page":"1108","article-title":"Chagas disease in Latin American migrants: a Spanish challenge","volume":"13","author":"Perez-Ayala","year":"2010"},{"key":"R46","series-title":"Med J Aust","first-page":"598","article-title":"Outpatient treatment of malaria in recently arrived African migrants","volume":"185","author":"Chih","year":"2006"},{"key":"R47","series-title":"J Paediatr Child Health","first-page":"509","article-title":"The epidemiology of health conditions of newly arrived refugee children: a review of patients attending a specialist health clinic in Sydney","volume":"45","author":"Sheikh","year":"2009"},{"key":"R48","series-title":"Emerg Infect Dis","first-page":"323","article-title":"Prolonged Plasmodium falciparum infection in immigrants, Paris","volume":"14","author":"D'Ortenzio","year":"2008"},{"key":"R49","series-title":"Am J Trop Med Hyg","first-page":"458","article-title":"Financial implications of refugee malaria: the impact of pre-departure presumptive treatment with anti-malarial drugs","volume":"77","author":"Collinet-Adler","year":"2007"},{"key":"R50","series-title":"Malar J","first-page":"22","article-title":"Pilot assessment of the sensitivity of the malaria thin film","volume":"7","author":"Ohrt","year":"2008"},{"key":"R51","series-title":"Pediatr Infect Dis J","first-page":"948","article-title":"Evaluation of malaria screening in newly arrived refugees to the United States by microscopy 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