{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T23:52:01Z","timestamp":1793404321830,"version":"4.5.0"},"reference-count":26,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,12,9]]},"abstract":"<jats:p>The standard treatment of mucosal leishmaniasis (ML) is pentavalent antimonials, agents with serious adverse effects. Alternative agents include amphotericin B deoxycholate and liposomal amphotericin B. We performed a retrospective study including 29 patients treated with liposomal amphotericin B, most of whom had comorbidities, history of previous treatment of ML, and contraindications to the use of antimonial pentavalent or amphotericin B deoxycholate. We observed a cure rate of 93.1%. Kidney failure was the most important side effect, reported in five patients (17.2%). This study showed a good efficacy and safety profile of liposomal amphotericin B in patients with ML and contraindications to the use of other agents.<\/jats:p>","DOI":"10.4269\/ajtmh.15-0033","type":"journal-article","created":{"date-parts":[[2015,10,20]],"date-time":"2015-10-20T12:33:15Z","timestamp":1445344395000},"page":"1214-1218","source":"Crossref","is-referenced-by-count":44,"title":["Efficacy and Safety of Liposomal Amphotericin B for the Treatment of Mucosal Leishmaniasis from the New World: A Retrospective Study"],"prefix":"10.4269","volume":"93","author":[{"given":"Mirella A.","family":"Cunha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aline C. Q.","family":"Le\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"de Cassia Soler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Angelo L.","family":"Lindoso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"ref1","series-title":"Expert Rev Anti Infect Ther","first-page":"419","article-title":"Current diagnosis and treatment of cutaneous and mucocutaneous leishmaniasis","volume":"8","author":"Goto","year":"2010"},{"key":"ref2","series-title":"J Am Acad Dermatol","first-page":"309","article-title":"New World cutaneous leishmaniasis: updated review of current and future diagnosis and treatment","volume":"63","author":"Mitropoulos","year":"2010"},{"key":"ref3","series-title":"Am J Trop Med Hyg","first-page":"818","article-title":"Can we use a lower dose of liposomal 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