{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T09:48:47Z","timestamp":1778665727502,"version":"3.51.4"},"reference-count":17,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,11,4]]},"abstract":"<jats:p>While visiting Malaysia, a 22-year-old previously healthy Japanese man developed myalgia, headache, and fever, leading to a diagnosis of classical dengue fever. After improvement and returning to Japan after a five day hospitalization, he developed productive cough several days after defervescing from dengue. Computed tomography (CT) thorax scan showed multiple lung cavities. A sputum smear revealed leukocytes with phagocytized gram-positive cocci in clusters, and grew an isolate <jats:italic>Staphylococcus aureus<\/jats:italic> sensitive to semi-synthetic penicillin; he was treated successfully with ceftriaxone and cephalexin. This second reported case of pneumonia due to <jats:italic>S. aureus<\/jats:italic> occurring after dengue fever, was associated both with nosocomial exposure and might have been associated with dengue-associated immunosuppression. Clinicians should pay systematic attention to bacterial pneumonia following dengue fever to establish whether such a connection is causally associated.<\/jats:p>","DOI":"10.4269\/ajtmh.15-0045","type":"journal-article","created":{"date-parts":[[2015,8,25]],"date-time":"2015-08-25T01:50:21Z","timestamp":1440467421000},"page":"1055-1057","source":"Crossref","is-referenced-by-count":9,"title":["Cavity Forming Pneumonia Due to Staphylococcus aureus Following Dengue Fever"],"prefix":"10.4269","volume":"93","author":[{"given":"Nobuyuki","family":"Miyata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukihiro","family":"Yoshimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natsuo","family":"Tachikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichiro","family":"Amano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yohei","family":"Sakamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youko","family":"Kosuge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"ref1","series-title":"Dengue","author":"World Health Organization"},{"key":"ref2","series-title":"BMJ Case Rep","article-title":"Staphylococcus aureus pneumonia and dengue virus co-infection and review of implications of coinfection","volume":"2012","author":"Nagassar","year":"2012"},{"key":"ref3","series-title":"Am J Trop Med Hyg","first-page":"221","article-title":"Clinical characteristics and risk factors for concurrent bacteremia in adults with dengue hemorrhagic fever","volume":"72","author":"Lee","year":"2005"},{"key":"ref4","series-title":"Ann Acad Med Singapore","first-page":"847","article-title":"Cluster of Staphylococcus aureus and dengue co-infection in Singapore","volume":"36","author":"Chai","year":"2007"},{"key":"ref5","series-title":"Am J Trop Med Hyg","first-page":"679","article-title":"Fatal Staphylococcal infection following classic dengue fever","volume":"83","author":"Ara\u00fajo","year":"2010"},{"key":"ref6","series-title":"Case Rep Infect Dis","first-page":"194205","article-title":"Dengue viral myositis complicated with rhabdomyolysis and superinfection of methicillin-resistant Staphylococcus aureus","volume":"2013","author":"Sunderalingam","year":"2013"},{"key":"ref7","series-title":"J Infect Dis","first-page":"47","article-title":"Mechanisms of immunosuppression in cytomegalovirus mononucleosis. II. 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