{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T09:50:18Z","timestamp":1778925018077,"version":"3.51.4"},"reference-count":28,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,9,7]]},"abstract":"<jats:p>Schistosomiasis is the second most significant parasitic disease in children in several African countries. For this purpose, the \u201cProgramme National de Lutte contre les Bilharzioses\u201d (PNLB) was developed in partnership with the World Health Organization (WHO) to control this disease in Senegal. However, geographic isolation of Bedik ethnic groups challenged implementation of the key elements of the schistosomiasis program in eastern Senegal, and therefore, a hospital was established in Ninefescha to improve access to health care as well as laboratory support for this population. The program we have implemented from 2008 in partnership with the PNLB\/WHO involved campaigns to 1) evaluate schistosomiasis prevalence in children of 53 villages around Ninefescha hospital, 2) perform a mass drug administration following the protocol established by the PNLB in school-aged children, 3) monitor annual prevalence, 4) implement health education campaigns, and 5) oversee the building of latrines. This campaign led to a drop in schistosomiasis prevalence but highlighted that sustainable schistosomiasis control by praziquantel treatment, awareness of the use of latrines, and inhabitants' voluntary commitment to the program are crucial to improve <jats:italic>Schistosoma<\/jats:italic> elimination. Moreover, this study revealed that preschool-aged children, for whom praziquantel was not recommended until 2014 in Senegal, constituted a significant reservoir for the parasite.<\/jats:p>","DOI":"10.4269\/ajtmh.15-0125","type":"journal-article","created":{"date-parts":[[2016,7,19]],"date-time":"2016-07-19T02:38:47Z","timestamp":1468895927000},"page":"614-622","source":"Crossref","is-referenced-by-count":11,"title":["Schistosomiasis Sustained Control Program in Ethnic Groups Around Ninefescha (Eastern Senegal)"],"prefix":"10.4269","volume":"95","author":[{"given":"Monique","family":"N'Diaye","sequence":"first","affiliation":[{"name":"1Universit\u00e9 de Caen Normandie, UNICAEN, UFR des Sciences Pharmaceutiques, Laboratoire de Parasitologie et Mycologie M\u00e9dicale, Caen, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elhadji M.","family":"Dioukhane","sequence":"additional","affiliation":[{"name":"2Centre de Sant\u00e9, Kedougou, Senegal."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Babacar","family":"Ndao","sequence":"additional","affiliation":[{"name":"3Ninefescha Hospital, Ninefescha, Senegal."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kemo","family":"Diedhiou","sequence":"additional","affiliation":[{"name":"4Programme National de Lutte contre les Bilharzioses\/World Health Organization Neglected Tropical Diseases, Dakar, Senegal."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lamine","family":"Diawara","sequence":"additional","affiliation":[{"name":"5Inter-country Support Team for West Africa, World Health Organization Neglected Tropical Diseases, Ouagadougou, Burkina Faso."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Idrissa","family":"Talla","sequence":"additional","affiliation":[{"name":"4Programme National de Lutte contre les Bilharzioses\/World Health Organization Neglected Tropical Diseases, Dakar, Senegal."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Vernet","sequence":"additional","affiliation":[{"name":"1Universit\u00e9 de Caen Normandie, UNICAEN, UFR des Sciences Pharmaceutiques, Laboratoire de Parasitologie et Mycologie M\u00e9dicale, Caen, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Bessin","sequence":"additional","affiliation":[{"name":"1Universit\u00e9 de Caen Normandie, UNICAEN, UFR des Sciences Pharmaceutiques, Laboratoire de Parasitologie et Mycologie M\u00e9dicale, Caen, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominique","family":"Barbier","sequence":"additional","affiliation":[{"name":"1Universit\u00e9 de Caen Normandie, UNICAEN, UFR des Sciences Pharmaceutiques, Laboratoire de Parasitologie et Mycologie M\u00e9dicale, Caen, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Dewavrin","sequence":"additional","affiliation":[{"name":"6Le Ka\u00efcedrat Association, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francis","family":"Klotz","sequence":"additional","affiliation":[{"name":"7Ecole du Val-de-Gr\u00e2ce, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Georges","sequence":"additional","affiliation":[{"name":"1Universit\u00e9 de Caen Normandie, UNICAEN, UFR des Sciences Pharmaceutiques, Laboratoire de Parasitologie et Mycologie M\u00e9dicale, Caen, France."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"ref1","series-title":"Lancet Infect Dis","first-page":"927","article-title":"Spatial distribution of schistosomiasis and treatment needs in sub-Saharan Africa: a systematic review and geostatistical analysis","volume":"15","author":"Lai","year":"2015"},{"key":"ref2","series-title":"Lancet Infect Dis","first-page":"733","article-title":"Schistosomiasis elimination: lessons from the past guide the future","volume":"10","author":"Gray","year":"2010"},{"key":"ref3","series-title":"Bull Soc Pathol Exot","first-page":"327","article-title":"Change of protocol in the verbal autopsy method and measure of malaria mortality in rural areas in Senegal [in French]","volume":"103","author":"Duthe","year":"2010"},{"key":"ref4","series-title":"Lancet","first-page":"2253","article-title":"Human schistosomiasis","volume":"383","author":"Colley","year":"2014"},{"key":"ref5","series-title":"Trends Parasitol","first-page":"197","article-title":"Schistosomiasis in African infants and preschool children: let them now be treated!","volume":"29","author":"Stothard","year":"2013"},{"key":"ref6","series-title":"Report of a Meeting to Review the Results of Studies on the Treatment of Schistosomiasis in Preschool-Aged Children","author":"World Health Organization","year":"2011"},{"key":"ref7","series-title":"Trans R Soc Trop Med Hyg","first-page":"182","article-title":"Preliminary study of the prevalence of human schistosomiasis in Richard-Toll (the Senegal River basin)","volume":"86","author":"Talla","year":"1992"},{"key":"ref8","series-title":"Int J Parasitol","first-page":"305","article-title":"Epidemiology of mixed Schistosoma mansoni and Schistosoma haematobium infections in northern Senegal","volume":"42","author":"Meurs","year":"2012"},{"key":"ref9","series-title":"Bull Soc Med Afr Noire Lang Fr","first-page":"288","article-title":"Existence of foci of bilharziosis due to S. mansoni in the upper Casamance region and in eastern Senegal [in French]","volume":"9","author":"Larivi\u00e8re","year":"1964"},{"key":"ref10","series-title":"N Engl J Med","first-page":"121","article-title":"A strategy to control transmission of Schistosoma japonicum in China","volume":"360","author":"Wang","year":"2009"},{"key":"ref11","series-title":"Schistosomiasis: Progress Report 2001\u20132011 and Strategic Plan 2012\u20132020","author":"World Health Organization","year":"2013"},{"key":"ref12","series-title":"Int Health","first-page":"103","article-title":"Treatment of intestinal schistosomiasis in Ugandan preschool children: best diagnosis, treatment efficacy and side-effects, and an extended praziquantel dosing pole","volume":"2","author":"Sousa-Figueiredo","year":"2010"},{"key":"ref13","series-title":"Parasitology","first-page":"1825","article-title":"Praziquantel: its use in control of schistosomiasis in sub-Saharan Africa and current research needs","volume":"136","author":"Doenhoff","year":"2009"},{"key":"ref14","series-title":"Pediatrics","first-page":"536","article-title":"Changing policy and practice in the control of pediatric schistosomiasis","volume":"135","author":"Mutapi","year":"2015"},{"key":"ref15","series-title":"PLoS Negl Trop Dis","first-page":"e1143","article-title":"Schistosoma haematobium treatment in 1\u20135 year old children: safety and efficacy of the antihelminthic drug praziquantel","volume":"5","author":"Mutapi","year":"2011"},{"key":"ref16","series-title":"Parasitology","first-page":"1593","article-title":"Closing the praziquantel treatment gap: new steps in epidemiological monitoring and control of schistosomiasis in African infants and preschool-aged children","volume":"138","author":"Stothard","year":"2011"},{"key":"ref17","series-title":"Parasit Vectors","first-page":"377","article-title":"Schistosoma mansoni among pre-school children in Musozi village, Ukerewe Island, north-western-Tanzania: prevalence and associated risk factors","volume":"8","author":"Ruganuza","year":"2015"},{"key":"ref18","series-title":"Parasit Vectors","first-page":"153","article-title":"Schistosomiasis in pre-school-age children and their mothers in Chikhwawa district, Malawi with notes on characterization of schistosomes and snails","volume":"7","author":"Poole","year":"2014"},{"key":"ref19","series-title":"Am J Trop Med Hyg","first-page":"32","article-title":"Epidemiology of schistosomiasis in two high-risk communities of south Cote d'Ivoire with particular emphasis on pre-school-aged children","volume":"89","author":"Coulibaly","year":"2013"},{"key":"ref20","series-title":"Parasitology","first-page":"835","article-title":"Schistosomiasis in infants and pre-school-aged children in sub-Saharan Africa: implication for control","volume":"139","author":"Ekpo","year":"2012"},{"key":"ref21","series-title":"Acta Trop","first-page":"212","article-title":"Schistosomiasis in infants and preschool-aged children: infection in a single Schistosoma haematobium and a mixed S. haematobium-S. mansoni foci of Niger","volume":"115","author":"Garba","year":"2010"},{"key":"ref22","series-title":"Parasit Vectors","first-page":"156","article-title":"The roles of water, sanitation and hygiene in reducing schistosomiasis: a review","volume":"8","author":"Grimes","year":"2015"},{"key":"ref23","series-title":"Acta Trop","first-page":"120","article-title":"High level of Schistosoma mansoni infection in pre-school children in Sierra Leone highlights the need in targeting this age group for praziquantel treatment","volume":"124","author":"Hodges","year":"2012"},{"key":"ref24","series-title":"Trop Med Int Health","first-page":"817","article-title":"Reinfection with Schistosoma haematobium following school-based chemotherapy with praziquantel in four highly endemic villages in Cote d'Ivoire","volume":"6","author":"N'Goran","year":"2001"},{"key":"ref25","series-title":"Acta Trop","first-page":"334","article-title":"Efficacy and safety of two closely spaced doses of praziquantel against Schistosoma haematobium and S. mansoni and re-infection patterns in school-aged children in Niger","volume":"128","author":"Garba","year":"2013"},{"key":"ref26","series-title":"Acta Trop","first-page":"143","article-title":"Increase of intestinal schistosomiasis after praziquantel treatment in a Schistosoma haematobium and Schistosoma mansoni mixed focus","volume":"73","author":"Ernould","year":"1999"},{"key":"ref27","series-title":"PLoS Negl Trop Dis","first-page":"e1774","article-title":"Significantly reduced intensity of infection but persistent prevalence of schistosomiasis in a highly endemic region in Mali after repeated treatment","volume":"6","author":"Landoure","year":"2012"},{"key":"ref28","series-title":"PLoS Negl Trop Dis","first-page":"e0004329","article-title":"Sustaining control of Schistosomiasis mansoni in western Cote d'Ivoire: results from a SCORE study, one year after initial praziquantel administration","volume":"10","author":"Assare","year":"2016"}],"container-title":["The American Society of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/95\/3\/article-p614.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/95\/3\/article-p614.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/95\/3\/article-p614.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T21:57:55Z","timestamp":1723067875000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/95\/3\/article-p614.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,7]]},"references-count":28,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.15-0125","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,7]]}}}