{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T21:01:26Z","timestamp":1786222886685,"version":"build-2736575974"},"reference-count":27,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,9,2]]},"abstract":"<jats:p>Ebola virus disease (EVD) is a life-threatening zoonosis caused by infection with the Ebola virus. Since the first reported EVD outbreak in the Democratic Republic of the Congo, several small outbreaks have been reported in central Africa with about 2,400 cases occurring between 1976 and 2013. The 2013\u20132015 EVD outbreak in west Africa is the first documented outbreak in this region and the largest ever with over 27,000 cases and more than 11,000 deaths. Although EVD transmission rates have recently decreased in west Africa, this crisis continues to threaten global health and security, particularly since infected travelers could spread EVD to other resource-limited areas of the world. Because vaccines and drugs are not yet licensed for EVD, outbreak control is dependent on the use of non-pharmaceutical interventions (e.g., infection control practices, isolation of EVD cases, contact tracing with follow-up and quarantine, sanitary burial, health education). However, delays in diagnosing and reporting EVD cases in less accessible rural areas continue to hamper control efforts. New advances in rapid diagnostics for identifying presumptive EVD cases and in mobile-based technologies for communicating critical health-related information should facilitate deployment of an early response to prevent the amplification of sporadic EVD cases into large-scale outbreaks.<\/jats:p>","DOI":"10.4269\/ajtmh.15-0229","type":"journal-article","created":{"date-parts":[[2015,7,15]],"date-time":"2015-07-15T01:31:01Z","timestamp":1436923861000},"page":"438-440","source":"Crossref","is-referenced-by-count":20,"title":["Ebola Virus Disease: Rapid Diagnosis and Timely Case Reporting are Critical to the Early Response for Outbreak Control"],"prefix":"10.4269","volume":"93","author":[{"given":"Lola V.","family":"Stamm","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"ref1","series-title":"Sci Transl Med","first-page":"253ps10","article-title":"Emerging viral diseases: confronting threats with new technologies","volume":"6","author":"Marston","year":"2014"},{"key":"ref2","series-title":"Ebola Situation Reports","author":"World Health Organization","year":"2015"},{"key":"ref3","series-title":"J Clin Microbiol","first-page":"4","article-title":"Ebola virus: a clear and present danger","volume":"53","author":"Burd","year":"2015"},{"key":"ref4","series-title":"Lancet","first-page":"573","article-title":"Isolation of Marburg-like virus from a case of haemorrhagic fever in Zaire","volume":"309","author":"Pattyn","year":"1977"},{"key":"ref5","series-title":"Vector Borne Zoonotic Dis","first-page":"723","article-title":"Human Ebola outbreak resulting from direct exposure to fruit bats in Luebo, Democratic Republic of Congo, 2007","volume":"9","author":"Leroy","year":"2009"},{"key":"ref6","series-title":"eLife","first-page":"e04395","article-title":"Mapping the zoonotic niche of Ebola virus disease in Africa","volume":"3","author":"Pigott","year":"2014"},{"key":"ref7","series-title":"EMBO Mol Med","first-page":"17","article-title":"Investigating the zoonotic origin of the west African Ebola epidemic","volume":"7","author":"Mar\u00ed Sa\u00e9z","year":"2014"},{"key":"ref8","series-title":"PLoS Negl Trop Dis","first-page":"e3056","article-title":"Outbreak of Ebola disease in Guinea: where ecology meets economy","volume":"8","author":"Bausch","year":"2014"},{"key":"ref9","article-title":"Cases of Ebola diagnosed in United States","author":"Centers for Disease Control and Prevention","year":"2014"},{"key":"ref10","series-title":"Lancet","first-page":"29","article-title":"Assessment of the potential for international dissemination of Ebola virus via commercial air travel during the 2014 west African outbreak","volume":"385","author":"Boguch","year":"2015"},{"key":"ref11","series-title":"Travel Med Infect Dis","first-page":"650","article-title":"Risk of imported Ebola virus disease in China","volume":"12","author":"Chen","year":"2014"},{"key":"ref12","series-title":"Travel Med Infect Dis","first-page":"688","article-title":"Ebola: a latent threat to Latin America. 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