{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:32:56Z","timestamp":1792801976734,"version":"4.5.0"},"reference-count":36,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,1,6]]},"abstract":"<jats:p>Information on the infectious causes of undifferentiated acute febrile illness (AFI) in Georgia is essential for effective treatment and prevention. In May 2008, a hospital-based AFI surveillance was initiated at six hospitals in Georgia. Patients aged \u2265 4 years with fever \u2265 38\u00b0C for \u2265 48 hours were eligible for surveillance. Blood culture and serologic testing were conducted for <jats:italic>Leptospira<\/jats:italic> spp., <jats:italic>Brucella<\/jats:italic> spp., West Nile virus (WNV), Crimean\u2013Congo hemorrhagic fever virus, <jats:italic>Coxiella burnetii<\/jats:italic>, tick-borne encephalitis virus (TBEV), hantavirus, <jats:italic>Salmonella enterica<\/jats:italic> serovar Typhi (<jats:italic>S.<\/jats:italic> Typhi), and <jats:italic>Rickettsia typhi<\/jats:italic>. Of 537 subjects enrolled, 70% were outpatients, 54% were males, and the mean age was 37 years. Patients reported having fatigue (89%), rigors (87%), sweating (83%), pain in joints (49%), and sleep disturbances (42%). Thirty-nine (7%) patients were seropositive for <jats:italic>R. typhi<\/jats:italic>, 37 (7%) for <jats:italic>Brucella<\/jats:italic> spp., 36 (7%) for TBEV, 12 (2%) for <jats:italic>Leptospira<\/jats:italic> spp., 10 (2%) for <jats:italic>C. burnetii<\/jats:italic>, and three (0.6%) for <jats:italic>S.<\/jats:italic> Typhi. None of the febrile patients tested positive for WNV antibodies. Of the patients, 73% were negative for all pathogens. Our results indicate that most of the targeted pathogens are present in Georgia, and highlight the importance of enhancing laboratory capacity for these infectious diseases.<\/jats:p>","DOI":"10.4269\/ajtmh.15-0400","type":"journal-article","created":{"date-parts":[[2015,10,6]],"date-time":"2015-10-06T00:12:26Z","timestamp":1444090346000},"page":"236-242","source":"Crossref","is-referenced-by-count":12,"title":["Hospital-Based Surveillance for Infectious Etiologies Among Patients with Acute Febrile Illness in Georgia, 2008\u20132011"],"prefix":"10.4269","volume":"94","author":[{"given":"Tinatin","family":"Kuchuloria","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paata","family":"Imnadze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nana","family":"Mamuchishvili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maiko","family":"Chokheli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tengiz","family":"Tsertsvadze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Endeladze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ketevan","family":"Mshvidobadze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lana","family":"Gatserelia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manana","family":"Makhviladze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marine","family":"Kanashvili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teona","family":"Mikautadze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Nanuashvili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khatuni","family":"Kiknavelidze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nora","family":"Kokaia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manana","family":"Makharadze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle 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