{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T03:12:34Z","timestamp":1789441954461,"version":"build-2803163510"},"reference-count":19,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,1,6]]},"abstract":"<jats:p>Dengue fever (DF) is a vector-borne disease caused by dengue viruses (DENVs). Epidemic dengue occurs intermittently in Taiwan. In 2014, Taiwan experienced its largest DF outbreak. There were 15,732 DF cases reported. There were a total of 136 dengue hemorrhagic fever (DHF) cases, of which 20 resulted in death. Most DF cases were reported in southern Taiwan. A total of 15,043 (96%) cases were from Kaohsiung, a modern city in southern Taiwan. This report reviews DF epidemics in Taiwan during 2005\u20132014. The correlation between DF and DHF along with temperature and precipitation were conjointly examined. We conclude that most dengue epidemics in Taiwan resulted from imported DF cases. Results indicate three main factors that may have been associated with this DF outbreak in Kaohsiung: an underground pipeline explosion combined with subsequent rainfall and higher temperature. These factors may have enhanced mosquito breeding activity, facilitating DENV transmission.<\/jats:p>","DOI":"10.4269\/ajtmh.15-0422","type":"journal-article","created":{"date-parts":[[2015,11,17]],"date-time":"2015-11-17T02:29:02Z","timestamp":1447727342000},"page":"193-197","source":"Crossref","is-referenced-by-count":59,"title":["Severe Dengue Fever Outbreak in Taiwan"],"prefix":"10.4269","volume":"94","author":[{"given":"Sheng-Fan","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Hung","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ko","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yen-Hsu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Pin","family":"Tseng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia-Hung","family":"Yen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deng-Chyang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Ming Arthur","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"ref1","series-title":"Nat Rev Microbiol","first-page":"S7","article-title":"Dengue: a continuing global threat","volume":"8","author":"Guzman","year":"2010"},{"key":"ref2","series-title":"Am J Trop Med Hyg","first-page":"349","article-title":"Molecular characterization and phylogenetic analysis of dengue viruses imported into Taiwan during 2008\u20132010","volume":"87","author":"Huang","year":"2012"},{"key":"ref3","series-title":"Am J Trop Med Hyg","first-page":"1039","article-title":"Molecular characterization of dengue viruses imported into Taiwan during 2003\u20132007: geographic distribution and genotype shift","volume":"80","author":"Shu","year":"2009"},{"key":"ref4","series-title":"Med J Armed Forces India","first-page":"67","article-title":"Discovery of fifth serotype of dengue virus (DENV-5): a new public health dilemma in dengue control","volume":"71","author":"Mustafa","year":"2015"},{"key":"ref5","series-title":"Emerg Infect Dis","first-page":"1603","article-title":"Dengue outbreaks in high-income area, Kaohsiung City, Taiwan, 2003\u20132009","volume":"18","author":"Lin","year":"2012"},{"key":"ref6","series-title":"Emerg Infect Dis","first-page":"552","article-title":"1998 dengue hemorrhagic fever epidemic in Taiwan","volume":"10","author":"Chao","year":"2004"},{"key":"ref7","series-title":"Taiwan National Infectious Disease Statistics System for Dengue Virus","author":"CDC","year":"2015"},{"key":"ref8","series-title":"BBC News","article-title":"Taiwan Gas Blasts in Kaohsiung Kill at Least 25","author":"Sui","year":"2014"},{"key":"ref9","series-title":"Trop Med Int Health","first-page":"598","article-title":"Dengue transmission in the Asia-Pacific region: impact of climate change and socio-environmental factors","volume":"16","author":"Banu","year":"2011"},{"key":"ref10","series-title":"PLoS Negl Trop 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illness","volume":"13","author":"Egger","year":"2007"},{"key":"ref15","series-title":"PLoS Negl Trop Dis","first-page":"e1180","article-title":"Age-specificity of clinical dengue during primary and secondary infections","volume":"5","author":"Thai","year":"2011"},{"key":"ref16","series-title":"Emerg Microbes Infect","first-page":"e46","article-title":"Large dengue virus type 1 outbreak in Taiwan","volume":"4","author":"Wang","year":"2015"},{"key":"ref17","series-title":"BMC Infect Dis","first-page":"182","article-title":"Airport sentinel surveillance and entry quarantine for dengue infections following a fever screening program in Taiwan","volume":"12","author":"Kuan","year":"2012"},{"key":"ref18","series-title":"Jpn J Infect Dis","article-title":"Biting density and distribution of Aedes albopictus during the September 2014 outbreak of dengue fever in Yoyogi Park and the vicinity in Tokyo Metropolis, Japan","author":"Tsuda","year":"2015"},{"key":"ref19","series-title":"Am J Trop Med 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