{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T05:18:04Z","timestamp":1772255884387,"version":"3.50.1"},"reference-count":58,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,1,6]]},"abstract":"<jats:p>\n                    Several recent studies have demonstrated that virulence in\n                    <jats:italic>Entamoeba histolytica<\/jats:italic>\n                    is triggered in the presence of both pathogenic and nonpathogenic bacteria species using in vitro and in vivo experimental animal models. In this study, we examined samples aspirated from abscess material obtained from patients who were clinically diagnosed with amebic liver abscess (ALA) or pyogenic liver abscess (PLA). To determine the diversity of bacterial species in the abscesses, we performed partial 16S rRNA gene sequencing. In addition, the\n                    <jats:italic>E. histolytica<\/jats:italic>\n                    and\n                    <jats:italic>Entamoeba dispar<\/jats:italic>\n                    species were genotyped using tRNA-linked short tandem repeats as specific molecular markers. The association between clinical data and bacterial and parasite genotypes were examined through a correspondence analysis. The results showed the presence of numerous bacterial groups. These taxonomic groups constitute common members of the gut microbiota, although all of the detected bacterial species have a close phylogenetic relationship with bacterial pathogens. Furthermore, some patients clinically diagnosed with PLA and ALA were coinfected with\n                    <jats:italic>E. dispar<\/jats:italic>\n                    or\n                    <jats:italic>E. histolytica<\/jats:italic>\n                    , which suggests that the virulence of these parasites increased in the presence of bacteria. However, no specific bacterial groups were associated with this effect. Together, our results suggest a nonspecific mechanism of virulence modulation by bacteria in\n                    <jats:italic>Entamoeba<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.4269\/ajtmh.15-0458","type":"journal-article","created":{"date-parts":[[2015,11,16]],"date-time":"2015-11-16T21:29:02Z","timestamp":1447709342000},"page":"147-155","source":"Crossref","is-referenced-by-count":22,"title":["Analysis of the Bacterial Diversity in Liver Abscess: Differences Between Pyogenic and Amebic Abscesses"],"prefix":"10.4269","volume":"94","author":[{"given":"Miriam E.","family":"Reyna-Fabi\u00e1n","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Zerme\u00f1o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecilia","family":"Xim\u00e9nez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janin","family":"Flores","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel F.","family":"Romero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Diaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jes\u00fas","family":"Argueta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Moran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alicia","family":"Valadez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ren\u00e9","family":"Cerritos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"ref1","series-title":"Arch Schiffs Tropenhyg Leipzig","first-page":"262","article-title":"Betrachtungen und experimentelle untersucchungen zur virulenz der Entamoeba histolytica beim 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