{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T08:45:51Z","timestamp":1783586751219,"version":"3.55.0"},"reference-count":44,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,2,3]]},"abstract":"<jats:p>This study evaluated the prevalence of <jats:italic>Strongyloides stercoralis<\/jats:italic> infection and human T-cell lymphotropic virus type 1 (HTLV-1) infection in the population. In addition, this study investigated the relationship between <jats:italic>S. stercoralis<\/jats:italic> infection or HTLV-1 infection and a patient's risk of developing related cancers. This is a retrospective cohort study of 5,209 patients. The prevalence of <jats:italic>S. stercoralis<\/jats:italic> infection was 5.2% among all patients. The prevalence among men (6.3%) was significantly higher than among women (3.6%, <jats:italic>P<\/jats:italic> &lt; 0.001). The prevalence of HTLV-1 infection among this population was 13.6% and the prevalence among women (15.5%) was significantly higher than that of men (12.3%, <jats:italic>P<\/jats:italic> &lt; 0.001). HTLV-1 seroprevalence was higher in patients with liver cancer (<jats:italic>P<\/jats:italic> = 0.003, odds ratio [OR]: 1.91, 95% confidence interval [CI]: 1.24, 2.95) and in those with lymphoma other than adult T-cell leukemia\/lymphoma (ATLL) (<jats:italic>P<\/jats:italic> = 0.005, adjusted OR: 2.76, 95% CI: 1.36, 5.62) if compared with patients without any neoplasm. The prevalence of both <jats:italic>S. stercoralis<\/jats:italic> and HTLV-1 in the Okinawan population has been steadily decreasing over the past 24 years. HTLV-1 infection significantly increases the odds of developing liver cancer and lymphomas other than ATLL.<\/jats:p>","DOI":"10.4269\/ajtmh.15-0556","type":"journal-article","created":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T03:48:05Z","timestamp":1448941685000},"page":"365-370","source":"Crossref","is-referenced-by-count":39,"title":["Relationship Among Strongyloides stercoralis Infection, Human T-Cell Lymphotropic Virus Type 1 Infection, and Cancer: A 24-Year Cohort Inpatient Study in Okinawa, Japan"],"prefix":"10.4269","volume":"94","author":[{"given":"Teruhisa","family":"Tanaka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuo","family":"Hirata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gretchen","family":"Parrott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miwa","family":"Higashiarakawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Kinjo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsu","family":"Kinjo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Hokama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiro","family":"Fujita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"ref1","series-title":"Jpn 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