{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T11:14:38Z","timestamp":1790075678000,"version":"4.0.1"},"reference-count":30,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,3,2]]},"abstract":"<jats:p>We report the case of a French traveler who developed acute pulmonary schistosomiasis 2 months after visiting Benin. He presented with a 1-month history of fever, cough, and thoracic pain. Initial investigations revealed hypereosinophilia and multiple nodular lesions on chest computed tomography scan. Lung biopsies were performed 2 months later because of migrating chest infiltrates and increasing eosinophilia. Histological examination showed schistosomal egg\u2013induced pulmonary granulomas with ova exhibiting a prominent terminal spine, resembling <jats:italic>Schistosoma haematobium<\/jats:italic>. However, egg shells were Ziehl\u2013Neelsen positive, raising the possibility of a <jats:italic>Schistosoma intercalatum<\/jats:italic> or a <jats:italic>Schistosoma guineensis<\/jats:italic> infection. Moreover, involvement of highly infectious hybrid species cannot be excluded considering the atypical early pulmonary oviposition. This case is remarkable because of the rarity of pulmonary schistosomiasis, its peculiar clinical presentation and difficulties in making species identification. It also emphasizes the need to consider schistosomiasis diagnosis in all potentially exposed travelers with compatible symptoms.<\/jats:p>","DOI":"10.4269\/ajtmh.15-0765","type":"journal-article","created":{"date-parts":[[2016,1,20]],"date-time":"2016-01-20T04:38:13Z","timestamp":1453264693000},"page":"611-614","source":"Crossref","is-referenced-by-count":11,"title":["Early Detection of Schistosoma Egg\u2013Induced Pulmonary Granulomas in a Returning Traveler"],"prefix":"10.4269","volume":"94","author":[{"given":"No\u00e9mie","family":"Coron","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohann","family":"Le Govic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sami","family":"Kettani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Pihet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandrine","family":"Hemery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludovic","family":"de Gentile","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Chabasse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"ref1","series-title":"Schistosomiasis","author":"World Health Organization","year":"2015"},{"key":"ref2","series-title":"Am J Trop Med Hyg","first-page":"729","article-title":"GeoSentinel Surveillance Network. Characteristics of schistosomiasis in travelers reported to the GeoSentinel Surveillance Network 1997\u20132008","volume":"79","author":"Nicolls","year":"2008"},{"key":"ref3","series-title":"Lancet Infect Dis","first-page":"218","article-title":"Katayama syndrome","volume":"7","author":"Ross","year":"2007"},{"key":"ref4","series-title":"Am J Med","first-page":"718","article-title":"Pulmonary manifestations of early schistosome infection among nonimmune travelers","volume":"109","author":"Schwartz","year":"2000"},{"key":"ref5","series-title":"Clin Infect Dis","first-page":"836","article-title":"Acute pulmonary schistosomiasis in travelers returning from Lake Malawi, sub-Saharan Africa","volume":"29","author":"Cooke","year":"1999"},{"key":"ref6","series-title":"J Travel Med","first-page":"235","article-title":"Acute schistosomiasis in travelers returning from Mali","volume":"2","author":"Colebunders","year":"1995"},{"key":"ref7","series-title":"Clin Microbiol Infect","first-page":"225","article-title":"Acute schistosomiasis, a diagnostic and therapeutic challenge","volume":"16","author":"Jaur\u00e9guiberry","year":"2010"},{"key":"ref8","series-title":"Travel Med Infect Dis","first-page":"209","article-title":"Acute pulmonary schistosomiasis in travelers: case report and review of the literature","volume":"10","author":"Pavlin","year":"2012"},{"key":"ref9","series-title":"J Trop Med Hyg","first-page":"289","article-title":"Frequency of schistosomiasis mansoni, of its clinicopathological forms and of the ectopic locations of the parasite in autopsies in Belo Horizonte, Brazil","volume":"98","author":"Gon\u00e7alves","year":"1995"},{"key":"ref10","series-title":"PLoS Negl Trop Dis","first-page":"e0003860","article-title":"Schistosoma mansoni eggs in spleen and lungs, mimicking other diseases","volume":"9","author":"Gobbi","year":"2015"},{"key":"ref11","series-title":"J Glob Infect Dis","first-page":"293","article-title":"Acute pulmonary schistosomiasis","volume":"3","author":"Baharoon","year":"2011"},{"key":"ref12","series-title":"Clin Microbiol Infect","first-page":"15","article-title":"Pulmonary vascular disease associated with parasitic infection\u2014the role of schistosomiasis","volume":"17","author":"Kolosionek","year":"2011"},{"key":"ref13","series-title":"Hum Pathol","first-page":"333","article-title":"The pathobiology of Schistosoma haematobium infection in humans","volume":"17","author":"Smith","year":"1986"},{"key":"ref14","series-title":"Semin Respir Infect","first-page":"159","article-title":"Cardiopulmonary manifestations of schistosomiasis","volume":"12","author":"Morris","year":"1997"},{"key":"ref15","series-title":"Gastroenterol Clin Biol","first-page":"582","article-title":"Shunt porto-cave intra-h\u00e9patique. Revue de la litt\u00e9rature, \u00e0 propos d'un cas","volume":"24","author":"Villar","year":"2000"},{"key":"ref16","series-title":"Atlas of the Global Distribution of Schistosomiasis","author":"World Health Organization","year":"1987"},{"key":"ref17","series-title":"Trans R Soc Trop Med Hyg","first-page":"545","article-title":"Schistosoma bovis eggs in human faeces","volume":"63","author":"McMahon","year":"1969"},{"key":"ref18","series-title":"Trans R Soc Trop Med Hyg","first-page":"849","article-title":"Schistosoma bovis in human stools in Kenya","volume":"80","author":"Chunge","year":"1986"},{"key":"ref19","series-title":"Trans R Soc Trop Med Hyg","first-page":"257","article-title":"Schistosoma bovis in human stools in Republic of Niger","volume":"82","author":"Mouchet","year":"1988"},{"key":"ref20","series-title":"Trans R Soc Trop Med Hyg","first-page":"18","article-title":"The specific differentiation of schistosome eggs by the Ziehl-Neelsen technique","volume":"66","author":"Muller","year":"1972"},{"key":"ref21","series-title":"Hum Pathol","first-page":"214","article-title":"Parasites in human tissues","volume":"27","author":"Thomas","year":"1996"},{"key":"ref22","series-title":"Med Mal Infect","first-page":"397","article-title":"Schistosoma intercalatum: crit\u00e8res \u00e9pid\u00e9miologiques de diff\u00e9renciation","volume":"9","author":"Bour\u00e9e","year":"1979"},{"key":"ref23","series-title":"Z F\u00fcr Parasitenkd Berl Ger","first-page":"145","article-title":"Schistosomiasis at Loum, Cameroun; Schistosoma haematobium, S. intercalatum and their natural hybrid","volume":"49","author":"Southgate","year":"1976"},{"key":"ref24","series-title":"Am J Trop Med Hyg","first-page":"332","article-title":"A new focus of Schistosoma haematobium\/S. intercalatum hybrid in Cameroon","volume":"45","author":"Ratard","year":"1991"},{"key":"ref25","series-title":"Bull Soci\u00e9t\u00e9 Pathol Exot","first-page":"183","article-title":"Schistosomiasis due to Schistosoma intercalatum and urbanization in central Africa","volume":"96","author":"Ripert","year":"2003"},{"key":"ref26","series-title":"Scientific World Journal","first-page":"793420","article-title":"Natural Interactions between S. haematobium and S. guineensis in the Republic of Benin","volume":"2012","author":"Mon\u00e9","year":"2012"},{"key":"ref27","series-title":"M\u00e9decine Trop Rev Corps Sant\u00e9 Colon","first-page":"163","article-title":"Pulmonary bilharziosis due to Schistosoma haematobium: pitfalls of species diagnosis. 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