{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T16:48:33Z","timestamp":1792601313773,"version":"4.5.0"},"reference-count":18,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,7,6]]},"abstract":"<jats:p>Leptospirosis is mainly considered an occupational disease, prevalent among agriculture, sewage works, forestry, and animal slaughtering populations. However, putative risk to miners and their inclusion in the high-risk leptospirosis group remain in need of rigorous analysis. Therefore, a study was conducted with the objective to assess the leptospirosis seroprevalence among miners of two districts of Tamil Nadu, India. A total of 244 sera samples from Pudukkottai miners (124) and Karur miners (120) were analyzed by microscopic agglutination test. Antibodies to leptospires were detected in 94 samples giving an overall seroprevalence of 38.5%. The seroprevalence was higher among Pudukkottai miners (65.3%) when compared with Karur miners (10.8%). Seroprevalence among control population (13%) was significantly less than that of the Pudukkottai miners marking a possible high-risk population group distinction. Subject sera most commonly reacted with organisms of the serogroup Autumnalis, and the pattern was similar in carrier animals of the study areas. Two leptospires were isolated from kidney samples of rats. The prevalence of Autumnalis among rodents and humans source tracked human leptospirosis among the miners. The study also determined that Pudukkottai miners are subjected to high-risk challenges such as exposure to water bodies on the way to the mines (odds ratio [OR] = 10.6), wet mine areas (OR = 10.6), rat infestation (OR = 4.6), and cattle rearing (OR = 10.4) and are thus frequently exposed to leptospirosis compared with Karur miners. Hence, control strategies targeting these populations will likely to prove to be effective remediation strategies benefiting Pudukkottai miners and workers in similar environments across occupations.<\/jats:p>","DOI":"10.4269\/ajtmh.16-0095","type":"journal-article","created":{"date-parts":[[2016,4,5]],"date-time":"2016-04-05T02:33:05Z","timestamp":1459823585000},"page":"38-42","source":"Crossref","is-referenced-by-count":17,"title":["Leptospirosis Seroprevalence Among Blue Metal Mine Workers of Tamil Nadu, India"],"prefix":"10.4269","volume":"95","author":[{"given":"Sakkarai Mohamed Asha","family":"Parveen","sequence":"first","affiliation":[{"name":"Medical Microbiology Laboratory, Department of Microbiology, Centre of Excellence in Life Sciences, Bharathidasan University, Tiruchirappalli, Tami Nadu, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baskar","family":"Suganyaa","sequence":"additional","affiliation":[{"name":"Medical Microbiology Laboratory, Department of Microbiology, Centre of Excellence in Life Sciences, Bharathidasan University, Tiruchirappalli, Tami Nadu, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muthu Sri","family":"Sathya","sequence":"additional","affiliation":[{"name":"Medical Microbiology Laboratory, Department of Microbiology, Centre of Excellence in Life Sciences, Bharathidasan University, Tiruchirappalli, Tami Nadu, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alphonse Asirvatham Princy","family":"Margreat","sequence":"additional","affiliation":[{"name":"Medical Microbiology Laboratory, Department of Microbiology, Centre of Excellence in Life Sciences, Bharathidasan University, Tiruchirappalli, Tami Nadu, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karikalacholan","family":"Sivasankari","sequence":"additional","affiliation":[{"name":"Medical Microbiology Laboratory, Department of Microbiology, Centre of Excellence in Life Sciences, Bharathidasan University, Tiruchirappalli, Tami Nadu, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santhanam","family":"Shanmughapriya","sequence":"additional","affiliation":[{"name":"Medical Microbiology Laboratory, Department of Microbiology, Centre of Excellence in Life Sciences, Bharathidasan University, Tiruchirappalli, Tami Nadu, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas E.","family":"Hoffman","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalimuthusamy","family":"Natarajaseenivasan","sequence":"additional","affiliation":[{"name":"Medical Microbiology Laboratory, Department of Microbiology, Centre of Excellence in Life Sciences, Bharathidasan University, Tiruchirappalli, Tami Nadu, India."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"ref1","series-title":"Curr Top Microbiol Immunol","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-3-662-45059-8_1","article-title":"History of leptospirosis","volume":"387","author":"Adler","year":"2015"},{"key":"ref2","series-title":"Lancet Infect Dis","first-page":"757","article-title":"Leptospirosis: a zoonotic disease of global importance","volume":"3","author":"Bharti","year":"2003"},{"key":"ref3","series-title":"Trans R Soc Trop Med Hyg","first-page":"94","article-title":"Serological evidence of leptospirosis in a human population following an outbreak of the disease in cattle","volume":"77","author":"Ratnam","year":"1983"},{"key":"ref4","series-title":"Indian J Med Res","first-page":"9","article-title":"Outbreak of leptospirosis with pulmonary involvement in north 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Hyg","first-page":"96","article-title":"Serological survey for leptospirosis in Trinidad among urban and rural dwellers and persons occupationally at risk","volume":"79","author":"Everard","year":"1985"}],"container-title":["The American Society of Tropical Medicine and 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