{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T15:02:39Z","timestamp":1758121359676},"reference-count":13,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,8,3]]},"abstract":"<jats:p>Cystic echinococcosis (CE) is a globally distributed zoonosis caused by the <jats:italic>Echinococcus granulosus<\/jats:italic> sensu lato species complex. Four approaches are available for treatment of abdominal CE: surgery, percutaneous aspiration, chemotherapy with albendazole, and watch-and-wait. Allocation of patients to these different treatment options mainly depends on the stage of the cystic lesion. However, as available guidelines are not widely followed, surgery is often applied even without the correct indication outside referral centers. This is not only a disadvantage for the patient, but also a waste of money. In this study, we evaluated the cost of the surgical approach for abdominal CE by analyzing hospitalization costs for 14 patients admitted to the General Surgery Ward at the \u201cSan Matteo\u201d Hospital Foundation in Pavia, Italy, from 2008 through 2014. We found that the total cost of a single hospitalization, including hospital stay, surgical intervention, personnel, drugs, and administrative costs ranged from \u20ac5,874 to 23,077 (median \u20ac11,033) per patient. Our findings confirm that surgery can be an expensive option. Therefore, surgical intervention should be limited to cyst types that do not benefit from nonsurgical therapies and appropriate case management can best be accomplished by using a cyst stage-specific approach.<\/jats:p>","DOI":"10.4269\/ajtmh.16-0187","type":"journal-article","created":{"date-parts":[[2016,6,7]],"date-time":"2016-06-07T03:04:20Z","timestamp":1465268660000},"page":"405-409","source":"Crossref","is-referenced-by-count":21,"title":["Costs Associated with Surgically Treated Cases of Abdominal Cystic Echinococcosis: A Single Center's Experience from 2008 to 2014, Pavia, Italy"],"prefix":"10.4269","volume":"95","author":[{"given":"Roberta","family":"Narra","sequence":"first","affiliation":[{"name":"1Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy."},{"name":"2World Health Organization Collaborating Centre for the Clinical Management of Cystic Echinococcosis, Pavia, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcello","family":"Maestri","sequence":"additional","affiliation":[{"name":"3Division of General Surgery, San Matteo Hospital Foundation, Pavia, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine M.","family":"Budke","sequence":"additional","affiliation":[{"name":"4Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Tamarozzi","sequence":"additional","affiliation":[{"name":"1Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy."},{"name":"2World Health Organization Collaborating Centre for the Clinical Management of Cystic Echinococcosis, Pavia, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mara","family":"Mariconti","sequence":"additional","affiliation":[{"name":"1Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy."},{"name":"2World Health Organization Collaborating Centre for the Clinical Management of Cystic Echinococcosis, Pavia, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni J.","family":"Nicoletti","sequence":"additional","affiliation":[{"name":"1Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy."},{"name":"2World Health Organization Collaborating Centre for the Clinical Management of Cystic Echinococcosis, Pavia, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Rinaldi","sequence":"additional","affiliation":[{"name":"1Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy."},{"name":"2World Health Organization Collaborating Centre for the Clinical Management of Cystic Echinococcosis, Pavia, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrico","family":"Brunetti","sequence":"additional","affiliation":[{"name":"1Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy."},{"name":"2World Health Organization Collaborating Centre for the Clinical Management of Cystic Echinococcosis, Pavia, Italy."},{"name":"5Division of Infectious and Tropical Diseases, San Matteo Hospital Foundation, Pavia, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"ref1","series-title":"Trop Med Health","first-page":"283","article-title":"Human echinococcosis: a neglected disease?","volume":"35","author":"Craig","year":"2007"},{"key":"ref2","series-title":"Parasitology","first-page":"S37","article-title":"Molecular epidemiology of cystic 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Italy","volume":"123","author":"Mastrandrea","year":"2012"},{"key":"ref7","series-title":"Gastroenterol Nurs","first-page":"363","article-title":"Understanding diagnostic related groups (DRGs) and inpatient hospital reimbursement","volume":"28","author":"Beaty","year":"2005"},{"key":"ref8","series-title":"World J Hepatol","first-page":"293","article-title":"Cystic echinococcosis of the liver: a primer for hepatologists","volume":"6","author":"Rinaldi","year":"2014"},{"key":"ref9","series-title":"Am J Trop Med Hyg","first-page":"48","article-title":"Efficacy and safety of PAIR for cystic echinococcosis: experience on a large series of patients from Bulgaria","volume":"84","author":"Golemanov","year":"2011"},{"key":"ref10","series-title":"Bull World Health Organ","first-page":"49","article-title":"Analysis of the economic impact of cystic echinococcosis in Spain","volume":"88","author":"Benner","year":"2010"},{"key":"ref11","series-title":"Emerg Infect 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