{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,14]],"date-time":"2024-09-14T09:03:27Z","timestamp":1726304607442},"reference-count":9,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,1,11]]},"abstract":"<jats:p>Orbital biopsy of nonspecific orbital inflammation, commonly referred to as \u201corbital pseudotumor,\u201d typically shows a combination of polyclonal lymphocytes, plasmocytes, leukocytes, macrophages, and variable degrees of collagen deposition. Herein, we report a patient with a positive history of mucocutaneous leishmaniasis who presented with an orbital mass with a histological profile of idiopathic orbital inflammation. Immunohistochemical and molecular analysis of the orbital specimens demonstrated that the orbital inflammation was associated with the presence of antigens of <jats:italic>Leishmania braziliensis<\/jats:italic> and DNA from the parasite.<\/jats:p>","DOI":"10.4269\/ajtmh.16-0389","type":"journal-article","created":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T01:20:20Z","timestamp":1477963220000},"page":"197-199","source":"Crossref","is-referenced-by-count":5,"title":["Sclerosing Orbital Inflammation Caused by Leishmania braziliensis"],"prefix":"10.4269","volume":"96","author":[{"given":"Antonio Augusto V.","family":"Cruz","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, School of Medicine of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliza V. C.","family":"Alves-Ferreira","sequence":"additional","affiliation":[{"name":"Department of Cell and Molecular Biology, School of Medicine of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gherusa","family":"Milbratz-Mor\u00e9","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, School of Medicine of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Chahud","sequence":"additional","affiliation":[{"name":"Department of Pathology, School of Medicine of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia C.","family":"Ruy","sequence":"additional","affiliation":[{"name":"Department of Cell and Molecular Biology, School of Medicine of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Irma Seixas","family":"Duarte","sequence":"additional","affiliation":[{"name":"Department of Pathology, School of Medicine of University of S\u00e3o Paulo, Sao Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela Kaysel","family":"Cruz","sequence":"additional","affiliation":[{"name":"Department of Cell and Molecular Biology, School of Medicine of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"ref1","series-title":"Ophthal Plast Reconstr Surg","first-page":"341","article-title":"Orbital pseudotumor: historical origin and modern relevance","volume":"29","author":"Grove","year":"2013"},{"key":"ref2","series-title":"Surv Ophthalmol","first-page":"66","article-title":"What is orbital pseudotumor?","volume":"41","author":"Mombaerts","year":"1996"},{"issue":"(Suppl 1)","key":"ref3","series-title":"Trans R Soc Trop Med Hyg","first-page":"S71","article-title":"A kinetoplast DNA minicircle probe (B18) specific for the Leishmania subgenus Viannia","volume":"96","author":"Gibson","year":"2002"},{"key":"ref4","series-title":"Parasitol Res","first-page":"1525","article-title":"Leishmania sp. identification by PCR associated with sequencing of target SSU rDNA in paraffin-embedded skin samples stored for more than 30 years","volume":"108","author":"de Lima","year":"2011"},{"key":"ref5","series-title":"J Mol Biol","first-page":"403","article-title":"Basic local alignment search tool","volume":"215","author":"Altschul","year":"1990"},{"key":"ref6","series-title":"Ophthal Plast Reconstr Surg","first-page":"79","article-title":"Idiopathic orbital inflammation: a pathogenetic construct and treatment strategy: the 2005 ASOPRS Foundation Lecture","volume":"22","author":"Harris","year":"2006"},{"key":"ref7","series-title":"Dermatol Ther (Heidelb)","first-page":"491","article-title":"Cutaneous and mucocutaneous leishmaniasis","volume":"22","author":"David","year":"2009"},{"key":"ref8","series-title":"PLoS Negl Trop Dis","first-page":"e0004018","article-title":"Differential gene expression and infection profiles of cutaneous and mucosal Leishmania braziliensis isolates from the same patient","volume":"9","author":"Alves-Ferreira","year":"2015"},{"key":"ref9","series-title":"Arch Ophthalmol","first-page":"852","article-title":"Mucosal leishmaniasis presenting as sinusitis and optic neuropathy","volume":"118","author":"Huna-Baron","year":"2000"}],"container-title":["The American Society of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/96\/1\/article-p197.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/96\/1\/article-p197.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/96\/1\/article-p197.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T22:38:29Z","timestamp":1723070309000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/96\/1\/article-p197.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,11]]},"references-count":9,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.16-0389","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"type":"print","value":"0002-9637"},{"type":"electronic","value":"1476-1645"}],"subject":[],"published":{"date-parts":[[2017,1,11]]}}}