{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T23:48:35Z","timestamp":1773877715395,"version":"3.50.1"},"reference-count":28,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,1,11]]},"abstract":"<jats:p>Though plans to eliminate malaria from the island of Hispaniola have recently received much attention, arbovirus surveillance continues to be largely neglected in Haiti. To support surveillance efforts and encourage vector-control strategies, a cross-sectional study of dengue virus (DENV) and West Nile virus (WNV) transmission was conducted using standard seroepidemiological methods. Blood samples (<jats:italic>N<\/jats:italic> = 673) were collected from 278 males and 395 females from three locations in the Ouest and Sud-Est Departments of Haiti. Serum was separated and tested for the presence of anti-DENV and anti-WNV immunoglobulin G (IgG) antibodies using an indirect enzyme-linked immunosorbent assay (ELISA). Anti-DENV IgG antibodies were detected in 72.1% (95% confidence interval [CI] = 68.7, 75.5) of the sample population; with no significant differences in seroprevalence by study location, participant gender, or age group (<jats:italic>P<\/jats:italic> &gt; 0.1, in all tests). Anti-WNV IgG antibodies were detected in only 1% (95% CI = 0.3, 1.8) of the sample population, all which originated from participants located in Gressier. The high prevalence of anti-DENV IgG antibodies among all age groups, including those in the youngest age group (2\u20135 years of age), suggests hyperendemic transmission of DENV in the Ouest and Sud-Est Departments of Haiti. In contrast, the relative absence of anti-WNV IgG antibodies, even among older population members, further supports the notion that WNV transmission in this population is largely absent. These findings highlight the large burden of disease from DENV and the need for enhanced arbovirus surveillance and implementation of vector control strategies throughout Haiti.<\/jats:p>","DOI":"10.4269\/ajtmh.16-0422","type":"journal-article","created":{"date-parts":[[2016,11,23]],"date-time":"2016-11-23T03:00:16Z","timestamp":1479870016000},"page":"135-140","source":"Crossref","is-referenced-by-count":12,"title":["A Tale of Two Flaviviruses: A Seroepidemiological Study of Dengue Virus and West Nile Virus Transmission in the Ouest and Sud-Est Departments of Haiti"],"prefix":"10.4269","volume":"96","author":[{"given":"Thomas A.","family":"Weppelmann","sequence":"first","affiliation":[{"name":"Herbert Wertheim College of Medicine, Florida International University, Miami, Florida."},{"name":"Emerging Pathogens Institute, University of Florida, Gainesville, Florida."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Burne","sequence":"additional","affiliation":[{"name":"Emerging Pathogens Institute, University of Florida, Gainesville, Florida."},{"name":"Department of Infectious Diseases and Pathology, College of Veterinary Medicine, University of Florida, Florida."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael E.","family":"von Fricken","sequence":"additional","affiliation":[{"name":"Emerging Pathogens Institute, University of Florida, Gainesville, Florida."},{"name":"Department of Global and Community Health, College of Health and Human Services, George Mason University, Fairfax, Virginia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maha A.","family":"Elbadry","sequence":"additional","affiliation":[{"name":"Emerging Pathogens Institute, University of Florida, Gainesville, Florida."},{"name":"Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville, Florida."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madsen","family":"Beau De Rochars","sequence":"additional","affiliation":[{"name":"Emerging Pathogens Institute, University of Florida, Gainesville, Florida."},{"name":"Department of Health Services, Research, Management, and Policy, College of Public Health and Health Professions, University of Florida, Gainesville, Florida."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques","family":"Boncy","sequence":"additional","affiliation":[{"name":"Department of Global and Community Health, College of Health and Human Services, George Mason University, Fairfax, Virginia."},{"name":"Laboratoire National de Sant\u00e9 Publique (LNSP), Minist\u00e8re de la Sant\u00e9 et de la Population (MSPP), Port au Prince, Haiti."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard A.","family":"Okech","sequence":"additional","affiliation":[{"name":"Emerging Pathogens Institute, University of Florida, Gainesville, Florida."},{"name":"Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville, Florida."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"ref1","series-title":"Emerg Med Pract","first-page":"1","article-title":"Emergency department management of mosquito-borne illness: malaria, dengue, and West Nile virus","volume":"16","author":"Caraballo","year":"2014"},{"key":"ref2","series-title":"Med Vet Entomol","first-page":"215","article-title":"Critical review of the vector status of Aedes albopictus","volume":"18","author":"Gratz","year":"2004"},{"key":"ref3","series-title":"Nat Rev Microbiol","first-page":"7","article-title":"Dengue: a continuing global threat","volume":"8","author":"Guzman","year":"2010"},{"key":"ref4","series-title":"Math 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methods","volume":"9","author":"Arnold","year":"2014"},{"key":"ref22","series-title":"Am J Trop Med Hyg","first-page":"630","article-title":"Serologic imprint of dengue virus in urban Haiti: characterization of humoral immunity to dengue in infants and young children","volume":"84","author":"Rioth","year":"2011"},{"key":"ref23","series-title":"Vet Res","first-page":"43","article-title":"Changing patterns of West Nile virus transmission: altered vector competence and host susceptibility","volume":"40","author":"Brault","year":"2009"},{"key":"ref24","series-title":"Science","first-page":"1062","article-title":"Linking breeding and wintering ranges of a migratory songbird using stable isotopes","volume":"295","author":"Rubenstein","year":"2002"},{"key":"ref25","series-title":"Int J Appl Earth Obs Geoinf","first-page":"203","article-title":"Evaluation of forest cover estimates for Haiti using supervised classification of Landsat 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