{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T01:18:06Z","timestamp":1776734286931,"version":"3.51.2"},"reference-count":14,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,11,2]]},"abstract":"<jats:p><jats:italic>Aspergillus<\/jats:italic> species produces a wide spectrum of fungal diseases like endophthalmitis and fungal keratitis ophthalmologically, but there has been no report about blepharitis caused by <jats:italic>Aspergilus flavus<\/jats:italic> to date. Herein, we report a 61-year-old ethnic Han Taiwanese male who had suffered from pain with burning and foreign body sensation after an insect bite on his left eye. Specimens from bilateral eyelids suggested infection of <jats:italic>A. flavus<\/jats:italic>, whereas corneal scraping showed the presence of Gram-negative bacteria. He was admitted for treatment of infectious keratitis with topical antibiotic and antifungal eye drops. Two weeks after discharge, recurrent blepharitis and keratitis of <jats:italic>A. flavus<\/jats:italic> was diagnosed microbiologically. Another treatment course of antifungal agent was resumed in the following 6 months, without further significant symptoms in the following 2 years. Collectively, it is possible for <jats:italic>A. flavus<\/jats:italic> to induce concurrent keratitis and blepharitis, and combined treatment of keratitis as well as blepharitis is advocated for as long as 6 months to ensure no recurrence.<\/jats:p>","DOI":"10.4269\/ajtmh.16-0453","type":"journal-article","created":{"date-parts":[[2016,9,13]],"date-time":"2016-09-13T02:38:53Z","timestamp":1473734333000},"page":"1216-1218","source":"Crossref","is-referenced-by-count":12,"title":["Recurrent Fungal Keratitis and Blepharitis Caused by Aspergillus flavus"],"prefix":"10.4269","volume":"95","author":[{"given":"Chia-Yi","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan."},{"name":"Department of Ophthalmology, Show Chwan Memorial Hospital, Changhua, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Ju","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi-Chin","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Chang Gung Memorial Hospital, Keelung, Taiwan."},{"name":"Department of Medicine, Chang Gung University College of Medicine, Taoyuan, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsin-Chiung","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan."},{"name":"Department of Medicine, Chang Gung University College of Medicine, Taoyuan, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching-Hsi","family":"Hsiao","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan."},{"name":"Department of Medicine, Chang Gung University College of Medicine, Taoyuan, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David Hui-Kang","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan."},{"name":"Department of Medicine, Chang Gung University College of Medicine, Taoyuan, Taiwan."},{"name":"Center for Tissue Engineering, Chang Gung Memorial Hospital, Linkou, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi-Chun","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan."},{"name":"Department of Medicine, Chang Gung University College of Medicine, Taoyuan, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hung-Chi","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan."},{"name":"Department of Medicine, Chang Gung University College of Medicine, Taoyuan, Taiwan."},{"name":"Center for Tissue Engineering, Chang Gung Memorial Hospital, Linkou, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"ref1","series-title":"N Engl J Med","first-page":"1870","article-title":"Aspergillosis","volume":"360","author":"Segal","year":"2009"},{"key":"ref2","series-title":"Int Ophthalmol","first-page":"291","article-title":"Detection of Aspergillus keratitis in ocular infections by culture and molecular method","volume":"31","author":"Badiee","year":"2011"},{"key":"ref3","series-title":"Mycoses","first-page":"206","article-title":"Aspergillus flavus: an emerging non-fumigatus Aspergillus species of significance","volume":"52","author":"Krishnan","year":"2009"},{"key":"ref4","series-title":"Doc Ophthalmol","first-page":"269","article-title":"Fungal keratitis in Saudi Arabia","volume":"79","author":"Khairallah","year":"1992"},{"key":"ref5","series-title":"Can J 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topical amphotericin B and natamycin","volume":"5","author":"O'Day","year":"1986"}],"container-title":["The American Society of Tropical Medicine and 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