{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T16:58:12Z","timestamp":1773766692124,"version":"3.50.1"},"reference-count":20,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,2,8]]},"abstract":"<jats:p>Vaccination is considered the most effective method to prevent rubella spread and congenital rubella syndrome (CRS). The aim of the present study was to investigate the rubella immunity among native and immigrant pregnant women in Taiwan. From 2000 to 2014, a total of 16,879 pregnant women who received routine prenatal examinations were recruited in this study. The rubella IgG antibodies were assayed using a microparticle enzyme immunoassay or chemiluminescent microparticle immunoassay. Subjects were categorized by nationality and subcategorized by specific periods of time for comparison. The rubella susceptibility was 12.7% in total, 11.1% in Taiwanese and 20.3% in immigrant population from 2000 to 2014. Among the immigrant women, those from Vietnam had the highest susceptibility (22.3%) and those from Thailand had the lowest susceptibility (3.8%). The immigrant women from Vietnam and China showed a significantly higher susceptibility compared with the native Taiwanese women in which the odds ratio was 2.30 (95% confidence interval [CI]: 2.04\u20132.60), 1.96 (95% CI: 1.59\u20132.41), respectively (<jats:italic>P<\/jats:italic> &lt; 0.001). It meant that immigrants from Vietnam and China had a higher likelihood of rubella susceptibility and related CRS sequela than native women. From 2000\u20132004 to 2010\u20132014 cohort, there was no obvious change in rubella susceptibility in native women, which varied between 10.0% and 11.9%. However, there was a decreasing trend of rubella susceptibility in the immigrant women overall, from 24.5% to 11.5% (<jats:italic>P<\/jats:italic> &lt; 0.001). To eliminate congenital rubella in Taiwan, additional catch-up immunization strategies are needed.<\/jats:p>","DOI":"10.4269\/ajtmh.16-0528","type":"journal-article","created":{"date-parts":[[2016,11,29]],"date-time":"2016-11-29T03:00:40Z","timestamp":1480388440000},"page":"411-414","source":"Crossref","is-referenced-by-count":1,"title":["Rubella Immunity in Pregnant Native Taiwanese and Immigrants from Asian Countries"],"prefix":"10.4269","volume":"96","author":[{"given":"Yeong-Hwa","family":"Zen","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Fooyin University Hospital, Pingtung, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching-Tang","family":"Shih","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, Fooyin University Hospital, Pingtung, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wan-Ju","family":"Kung","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Fooyin University Hospital, Pingtung, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chien-Hung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Public Health, Kaohsiung Medical University, Kaohsiung, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching-Chiang","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Fooyin University Hospital, Pingtung, Taiwan."},{"name":"Department of Medical Laboratory Science and Biotechnology, Fooyin University, Kaohsiung, Taiwan."},{"name":"Department of Education and Research, Fooyin University Hospital, Pingtung, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"ref1","series-title":"Prenat Diagn","first-page":"1246","article-title":"Rubella and pregnancy: diagnosis, management and outcomes","volume":"34","author":"Bouthry","year":"2014"},{"key":"ref2","series-title":"Global Vaccine Action Plan (GVAP) Secretariat report 2015","author":"World Health Organization","year":"2016"},{"key":"ref3","series-title":"BJOG","first-page":"706","article-title":"Rubella seroepidemiology and estimations of the catch-up immunization rate and persistence of antibody titers in pregnant women in Taiwan","volume":"118","author":"Lin","year":"2011"},{"key":"ref4","author":"Department of Household Registration, Ministry of the Interior, Taiwan","year":"2016"},{"key":"ref5","series-title":"J Clin Virol","first-page":"152","article-title":"Rubella epidemic in Vietnam: characteristic of rubella virus genes from pregnant women and their fetuses\/newborns with congenital rubella syndrome","volume":"57","author":"Pham","year":"2013"},{"key":"ref6","series-title":"Virol J","first-page":"122","article-title":"Rubella epidemic caused by genotype 1E rubella viruses in Beijing, China, in 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Syst Rev","first-page":"CD010752","article-title":"Postpartum rubella vaccination for sero-negative women","author":"Alzeidan","year":"2013"},{"key":"ref17","series-title":"Vaccine","first-page":"635","article-title":"Determining rubella immunity in pregnant Alberta women 2009\u20132012","volume":"33","author":"Lai","year":"2015"},{"key":"ref18","series-title":"Vaccine","first-page":"1767","article-title":"Rubella susceptibility in pregnant women and results of a postpartum immunization strategy in Catalonia, Spain","volume":"33","author":"Vilajeliu","year":"2015"},{"key":"ref19","series-title":"Br J Midwifery","first-page":"16","article-title":"Post-partum MMR immunization rates in rubella-susceptible antenatal women","volume":"21","author":"Matthews","year":"2013"},{"key":"ref20","series-title":"Am J Trop Med Hyg","first-page":"40","article-title":"Rubella seroepidemiology and catch-up immunization among pregnant women in Taiwan: comparison between women born in Taiwan and immigrants from six countries in Asia","volume":"82","author":"Lin","year":"2010"}],"container-title":["The American Society of Tropical Medicine and 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