{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:48:46Z","timestamp":1761490126066},"reference-count":18,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,1,11]]},"abstract":"<jats:p>Dried blood spots (DBS) were collected from 805 children attending 42 elementary schools in the regions of Mopti, Sikasso, Koulikoro, and the regional capital of Bamako in Mali as part of an evaluation of a school health intervention. Eluted immunoglobulin (Ig) G from the DBS was assessed by a multiplex bead assay (MBA) for two filariasis antigens, <jats:italic>Wuchereria bancrofti<\/jats:italic>, Wb123, and <jats:italic>Brugia malayi<\/jats:italic>, Bm14, to determine the effectiveness of mass drug administration (MDA) programs to eliminate lymphatic filariasis (LF). The prevalence of positive IgG responses in the children to each antigen was less than 1%, indicating effectiveness of the MDA against LF. The MBA is an excellent serological platform that provides cost-effective opportunities to evaluate public health activities beyond the survey targets.<\/jats:p>","DOI":"10.4269\/ajtmh.16-0560","type":"journal-article","created":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T01:20:20Z","timestamp":1477963220000},"page":"229-232","source":"Crossref","is-referenced-by-count":4,"title":["Serological Responses to Filarial Antigens in Malian Children Attending Elementary Schools"],"prefix":"10.4269","volume":"96","author":[{"given":"Delynn M.","family":"Moss","sequence":"first","affiliation":[{"name":"Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna N.","family":"Chard","sequence":"additional","affiliation":[{"name":"Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Trinies","sequence":"additional","affiliation":[{"name":"Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seydou","family":"Doumbia","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Odontostomatology, Malaria Research and Training Center, University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew C.","family":"Freeman","sequence":"additional","affiliation":[{"name":"Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick J.","family":"Lammie","sequence":"additional","affiliation":[{"name":"Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"year":"2015","series-title":"Lymphatic Filariasis Epidemiology","author":"World Health Organization","key":"ref1"},{"year":"2012","series-title":"Accelerating Work to Overcome the Global Impact of Neglected Tropical Diseases: A Roadmap for Implementation","author":"World Health Organization","key":"ref2"},{"key":"ref3","series-title":"PLoS Negl Trop Dis","first-page":"e3333","article-title":"Assessing progress in reducing the at-risk population after 13 years of the global programme to eliminate lymphatic filariasis","volume":"8","author":"Hooper","year":"2014"},{"key":"ref4","series-title":"PLoS Negl Trop Dis","first-page":"e3319","article-title":"Progress and impact of 13 years of the global programme to eliminate lymphatic filariasis on reducing the burden of filarial disease","volume":"8","author":"Ramaiah","year":"2014"},{"key":"ref5","series-title":"Am J Trop Med Hyg","first-page":"356","article-title":"The impact of six annual rounds of mass drug administration on Wuchereria bancrofti infections in humans and in mosquitoes in Mali","volume":"93","author":"Coulibaly","year":"2015"},{"key":"ref6","series-title":"Parasit Vectors","first-page":"247","article-title":"Wuchereria bancrofti transmission pattern in southern Mali prior to and following the institution of mass drug administration","volume":"6","author":"Coulibaly","year":"2013"},{"year":"2016","series-title":"Mali Work Plan, FY 2016, Project Year 5. October 2015\u2013September 2016","author":"Envision","key":"ref7"},{"key":"ref8","series-title":"Am J Trop Med Hyg","first-page":"1418","article-title":"The impact of a school-based water, sanitation, and hygiene program on absenteeism, diarrhea, and respiratory infection: a matched-control trial in Mali","volume":"94","author":"Trinies","year":"2016"},{"key":"ref9","series-title":"PLoS Negl Trop Dis","first-page":"e1941","article-title":"Longitudinal monitoring of the development of antifilarial antibodies and acquisition of Wuchereria bancrofti in a highly endemic area of Haiti","volume":"6","author":"Hamlin","year":"2012"},{"key":"ref10","series-title":"Filaria J","first-page":"9","article-title":"Recombinant antigen-based antibody assays for the diagnosis and surveillance of lymphatic filariasis: a multicenter trial","volume":"3","author":"Lammie","year":"2004"},{"key":"ref11","series-title":"Am J Trop Med Hyg","first-page":"229","article-title":"Multiplex bead assay for serum samples from children in Haiti enrolled in a drug study for the treatment of lymphatic filariasis","volume":"85","author":"Moss","year":"2011"},{"key":"ref12","series-title":"PLoS Negl Trop Dis","first-page":"e1873","article-title":"CT694 and pgp3 as serological tools for monitoring trachoma programs","volume":"6","author":"Goodhew","year":"2012"},{"key":"ref13","series-title":"Am J Trop Med Hyg","first-page":"653","article-title":"Longitudinal evaluation of enteric protozoa in Haitian children by stool exam and multiplex serologic assay","volume":"90","author":"Moss","year":"2014"},{"key":"ref14","series-title":"Trends Parasitol","first-page":"78","article-title":"Diagnostic tools for filariasis elimination programs","volume":"23","author":"Weil","year":"2007"},{"key":"ref15","series-title":"PLoS Negl Trop Dis","first-page":"e1930","article-title":"Identification of Wb123 as an early and specific marker of Wuchereria bancrofti infection","volume":"6","author":"Kubofcik","year":"2012"},{"key":"ref16","series-title":"Cytometry","first-page":"27","article-title":"Multiplexed fluorescent bead-based immunoassays for quantitation of human cytokines in serum and culture supernatants","volume":"45","author":"Kellar","year":"2001"},{"key":"ref17","series-title":"J Immunol Methods","first-page":"98","article-title":"Development of a multiplexed fluorescent immunoassay for the quantitation of antibody responses to four Neisseria meningitidis serogroups","volume":"342","author":"Martins","year":"2009"},{"key":"ref18","series-title":"Clin Diagn Lab Immunol","first-page":"872","article-title":"Comparison of a multiplex flow cytometric assay with enzyme-linked immunosorbent assay for quantitation of antibodies to tetanus, diphtheria, and Haemophilus influenzae Type b","volume":"9","author":"Pickering","year":"2002"}],"container-title":["The American Society of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/96\/1\/article-p229.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/96\/1\/article-p229.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/96\/1\/article-p229.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T22:38:19Z","timestamp":1723070299000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/96\/1\/article-p229.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,11]]},"references-count":18,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.16-0560","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"type":"print","value":"0002-9637"},{"type":"electronic","value":"1476-1645"}],"subject":[],"published":{"date-parts":[[2017,1,11]]}}}