{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:50:11Z","timestamp":1787068211705,"version":"build-2736575974"},"reference-count":24,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,11,8]]},"abstract":"<jats:p>\n                    A 15-year-old Thai girl was referred to the Hospital for Tropical Diseases of Mahidol University with a 3-week history of an intermittent migratory mass on the forehead. She was diagnosed with cutaneous gnathostomiasis. The patient was treated with albendazoleat 400 mg orally twice a day for 3 weeks, with good compliance. She revisited the hospital after 3 months and was seen to have been unresponsive to the initial treatment. There was intermittent swelling in her right upper eyelid along with mild redness around her right upper and lower eyelids. Another attempt of treatment was made with ivermectin 0.2 mg\/kg\/day for two consecutive days. This is a case of gnathostomiasis in full sequence, with complete follow-up. The case report starts from the beginning of the symptoms until the antibodies against\n                    <jats:italic>Gnathostoma spinigerum<\/jats:italic>\n                    decline to negative, confirmed by the western blot test. It took around 18 months to see the western blot test change to a negative result. The resolved clinical symptoms were possibly due to the responsiveness of the patient to ivermectin or the albendazole and ivermectin combination or even the coadministration of antibiotics afterward.\n                  <\/jats:p>","DOI":"10.4269\/ajtmh.17-0239","type":"journal-article","created":{"date-parts":[[2017,8,8]],"date-time":"2017-08-08T03:00:28Z","timestamp":1502161228000},"page":"1611-1615","source":"Crossref","is-referenced-by-count":11,"title":["Case Report: Clinical Features of Intermittent Migratory Swelling Caused by Gnathostomiasis with Complete Follow-up"],"prefix":"10.4269","volume":"97","author":[{"given":"Chollasap","family":"Sharma","sequence":"first","affiliation":[{"name":"Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Watcharapong","family":"Piyaphanee","sequence":"additional","affiliation":[{"name":"Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorn","family":"Watthanakulpanich","sequence":"additional","affiliation":[{"name":"Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","author":"Dekumyoy","year":"2013"},{"key":"b2","author":"Dekumyoy","year":"2012"},{"key":"b3","series-title":"J Parasitol Trop Med Assoc Thailand","first-page":"1","article-title":"The world\u2019s first-story of Gnathostoma spinigerum infection in the young Thai woman","volume":"6","author":"Daengswang","year":"1983"},{"key":"b4","author":"Miyasaki","year":"1991"},{"key":"b5","author":"Daengsvang","year":"1986"},{"key":"b6","series-title":"Int J Parasitol","first-page":"677","article-title":"Purification of Gnathostoma spinegerum specific antigen and immunodiagnosis of human gnathostomiasis","volume":"21","author":"Nopparatana","year":"1991"},{"key":"b7","series-title":"Am J Trop Med Hyg","first-page":"623","article-title":"Treatment of cutaneous gnathostomiasis with ivermectin","volume":"71","author":"Kraivichian","year":"2004"},{"key":"b8","series-title":"Southeast Asian J Trop Med Public Health","first-page":"650","article-title":"Double-dose ivermectinvsalbendazole for the treatment of gnathostomiasis","volume":"36","author":"Nontasut","year":"2005"},{"key":"b9","series-title":"Am J Trop Med Hyg","first-page":"707","article-title":"Case report: gnathostomiasis in two travelers to Zambia","volume":"68","author":"Hale","year":"2003"},{"key":"b10","series-title":"Emerg Infect Dis","first-page":"594","article-title":"Gnathostomiasis acquired by British tourists in Botswana","volume":"15","author":"Herman","year":"2009"},{"key":"b11","series-title":"Clin Infect Dis","first-page":"1297","article-title":"Sushi delights and parasites: the risk of fishborne and foodborne parasitic zoonosis in Asia","volume":"41","author":"Nawa","year":"2005"},{"key":"b12","author":"Dekumyoy","year":"2014"},{"key":"b13","author":"Daengsvang","year":"1980"},{"key":"b14","series-title":"Am J Trop Med Hyg","first-page":"33","article-title":"Long-term follow-up of imported gnathostomiasis shows frequent treatment failure","volume":"80","author":"Strady","year":"2009"},{"key":"b15","series-title":"J Trop Med Parasitol","first-page":"79","article-title":"The infectivity of frozen Gnathostoma spinigerum encysted larvae in mice","volume":"25","author":"Rojekittikhun","year":"2002"},{"key":"b16","series-title":"Am J Trop Med Hyg","first-page":"316","article-title":"Short report: gnathostomiasis in Mexico","volume":"58","author":"Ogata","year":"1998"},{"key":"b17","series-title":"J Trop Med Parasitol","first-page":"623","article-title":"Treatment of cutaneous gnathostomiasis with ivermectin","volume":"71","author":"Kraivichian","year":"2004"},{"key":"b18","series-title":"J Trop Med Parasitol","first-page":"77","article-title":"Ocular gnathostomiasis: a comprehensive review","volume":"33","author":"Nawa","year":"2010"},{"key":"b19","series-title":"Retina","first-page":"438","article-title":"Intraocular Gnathostoma spinigerum. Clinicopathologic study of two cases with review of literature","volume":"14","author":"Biswas","year":"1994"},{"key":"b20","author":"Waikagul","year":"2007"},{"key":"b21","author":"Kaplan","year":"2012"},{"key":"b22","series-title":"Clin Infect Dis","first-page":"E17","article-title":"Ivermectin treatment of traveler who returned from Peru with cutaneous gnathostomiasis","volume":"33","author":"Chappuis","year":"2001"},{"key":"b23","series-title":"Emerg Infect Dis","first-page":"647","article-title":"Gnathostomiasis: an emerging imported disease","volume":"9","author":"Moore","year":"2003"},{"key":"b24","series-title":"Emerg Infect Dis","first-page":"1690","article-title":"Eosinophilic pleural effusion in gnathostomiasis","volume":"10","author":"Parola","year":"2004"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/97\/5\/article-p1611.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/97\/5\/article-p1611.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/97\/5\/article-p1611.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T12:51:40Z","timestamp":1722430300000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/97\/5\/article-p1611.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,8]]},"references-count":24,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.17-0239","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,8]]}}}