{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:24:16Z","timestamp":1791293056333,"version":"4.1.0"},"reference-count":19,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,6,6]]},"abstract":"<jats:p>In September 2014, an increase in the number of <jats:italic>Cryptosporidium<\/jats:italic> spp. gastrointestinal tract infections was reported over a 6-month period among children living in a remote area along the Maroni River in French Guiana. Children presented gastroenteritis symptoms with <jats:italic>Cryptosporidium<\/jats:italic>-positive stools. Questionnaires were administered and stool examinations were controlled 3 months after the onset of symptoms. Data collection included demographics, food consumption, river behavior, symptoms, and outcome. Stool specimens were tested using microscopy and polymerase chain reaction. Samples from the water systems were examined for turbidity and culture for bacteria. Data from the reference laboratory were analyzed to calculate the median cryptosporidiosis incidence among immunocompetent patients from 2008 to 2015. Data on gastroenteritis cases reported by the Delocalized Center for Prevention and Care in the area were also collected. We report a cluster of 14 cases. All cases were children, aged between 4.5 and 38 months. Seven reported moderate to severe dehydration and required hospitalization. Speciation and microbiological typing revealed the cluster strain was <jats:italic>Cryptosporidium hominis<\/jats:italic> subtype IbA10G2 but <jats:italic>C. hominis<\/jats:italic> IbA9G2 and IbA15G1 strains were also identified. The median incidence in French Guiana was 5.8 cases per year before the outbreak. The first cases of the cluster appeared in the dry season. We describe the clinical features, epidemiology, and state of current investigations for the largest documented outbreak of cryptosporidiosis in French Guiana.<\/jats:p>","DOI":"10.4269\/ajtmh.17-0609","type":"journal-article","created":{"date-parts":[[2018,4,24]],"date-time":"2018-04-24T07:00:34Z","timestamp":1524553234000},"page":"1727-1732","source":"Crossref","is-referenced-by-count":17,"title":["Cryptosporidiosis Outbreak in Immunocompetent Children from a Remote Area of French Guiana"],"prefix":"10.4269","volume":"98","author":[{"given":"Emilie","family":"Mosnier","sequence":"first","affiliation":[{"name":"Centres D\u00e9localis\u00e9s de Pr\u00e9vention et de Soins, Centre Hospitalier Andr\u00e9e Rosemon, Cayenne, Guyane, France;"},{"name":"Ecosyst\u00e8mes amazoniens et Pathologie Tropicale, Universit\u00e9 de la Guyane, Cayenne, Guyane, France;"},{"name":"Unit\u00e9 de Maladies Infectieuses et Tropicales, Centre hospitalier Andr\u00e9e Rosemon, Cayenne, Guyane, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"No\u00e9mie","family":"Martin","sequence":"additional","affiliation":[{"name":"Centres D\u00e9localis\u00e9s de Pr\u00e9vention et de Soins, Centre Hospitalier Andr\u00e9e Rosemon, Cayenne, Guyane, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romy","family":"Razakandrainibe","sequence":"additional","affiliation":[{"name":"Laboratoire de Parasitologie et Mycologie, Centre Hospitalier Universitaire Charles Nicolle, Rouen, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Dalle","sequence":"additional","affiliation":[{"name":"Laboratoire de Parasitologie Mycologie, CHU Dijon, Dijon, France;"},{"name":"UMR PAM Universit\u00e9 de Bourgogne\/AgrSup, Dijon, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Roux","sequence":"additional","affiliation":[{"name":"Laboratoire de Parasitologie et Mycologie, Centre hospitalier Andr\u00e9e Rosemon, Cayenne, Guyane, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaud","family":"Buteux","sequence":"additional","affiliation":[{"name":"Laboratoire de Parasitologie et Mycologie, Centre hospitalier Andr\u00e9e Rosemon, Cayenne, Guyane, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lo\u00efc","family":"Favennec","sequence":"additional","affiliation":[{"name":"Laboratoire de Parasitologie et Mycologie, Centre Hospitalier Universitaire Charles Nicolle, Rouen, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Brousse","sequence":"additional","affiliation":[{"name":"Centres D\u00e9localis\u00e9s de Pr\u00e9vention et de Soins, Centre Hospitalier Andr\u00e9e Rosemon, Cayenne, Guyane, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basma","family":"Guarmit","sequence":"additional","affiliation":[{"name":"Centres D\u00e9localis\u00e9s de Pr\u00e9vention et de Soins, Centre Hospitalier Andr\u00e9e Rosemon, Cayenne, Guyane, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Blanchet","sequence":"additional","affiliation":[{"name":"Ecosyst\u00e8mes amazoniens et Pathologie Tropicale, Universit\u00e9 de la Guyane, Cayenne, Guyane, France;"},{"name":"Laboratoire de Parasitologie et Mycologie, Centre hospitalier Andr\u00e9e Rosemon, Cayenne, Guyane, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lo\u00efc","family":"Epelboin","sequence":"additional","affiliation":[{"name":"Ecosyst\u00e8mes amazoniens et Pathologie Tropicale, Universit\u00e9 de la Guyane, Cayenne, Guyane, France;"},{"name":"Unit\u00e9 de Maladies Infectieuses et Tropicales, Centre hospitalier Andr\u00e9e Rosemon, Cayenne, Guyane, 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France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Nacher","sequence":"additional","affiliation":[{"name":"Ecosyst\u00e8mes amazoniens et Pathologie Tropicale, Universit\u00e9 de la Guyane, Cayenne, Guyane, France;"},{"name":"Centre d\u2019Investigation Clinique Epid\u00e9miologie Clinique Antilles Guyane, Centre hospitalier Andr\u00e9e Rosemon, Cayenne, Guyane, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magalie","family":"Demar","sequence":"additional","affiliation":[{"name":"Ecosyst\u00e8mes amazoniens et Pathologie Tropicale, Universit\u00e9 de la Guyane, Cayenne, Guyane, France;"},{"name":"Unit\u00e9 de Maladies Infectieuses et Tropicales, Centre hospitalier Andr\u00e9e Rosemon, Cayenne, Guyane, France;"},{"name":"Laboratoire de Parasitologie et Mycologie, Centre hospitalier Andr\u00e9e Rosemon, Cayenne, Guyane, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Indian Pediatr","first-page":"906","article-title":"Cryptosporidium in children with diarrhea: a hospital-based study","volume":"51","author":"Bera","year":"2014"},{"key":"b2","series-title":"Lancet Infect Dis","first-page":"85","article-title":"A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium","volume":"15","author":"Checkley","year":"2015"},{"key":"b3","series-title":"Lancet","first-page":"209","article-title":"Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study","volume":"382","author":"Kotloff","year":"2013"},{"key":"b4","series-title":"PLoS Negl Trop Dis","first-page":"e0004729","article-title":"The burden of Cryptosporidium diarrheal disease among children < 24 months of age in 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