{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:37:28Z","timestamp":1790127448592,"version":"4.0.1"},"reference-count":18,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,5,9]]},"abstract":"<jats:p>Dengue fever (DF) is a mosquito-borne acute viral disease presenting with hemorrhagic manifestations in severe cases. Southeast Iran is in close proximity to Pakistan, an endemic country for DF. This cross-sectional study was conducted in the Sistan and Baluchestan province in the southeast of Iran to investigate possibility of DF (immunoglobulin M [IgM], immunoglobulin G [IgG], and nonstructural protein 1 [NS1] antigen tests) in 60 clinically suspected patients (April 2013 to August 2015). NS1 protein was detected in 5% (<jats:italic>N<\/jats:italic> = 3), at least one of the antibodies (IgM and\/ or IgG) was detected in 11% (<jats:italic>N<\/jats:italic> = 7) of the samples. Five patients identified as of acutely infected. There was a simultaneous presence of NS1 protein and IgG or IgM antibodies in 4% (<jats:italic>N<\/jats:italic> = 2) of patients. Previous studies show establishment of potential vectors in this area. These evidences support the hypothesis that DF can be a health concern in Southeast Iran with potential future outbreaks.<\/jats:p>","DOI":"10.4269\/ajtmh.17-0634","type":"journal-article","created":{"date-parts":[[2018,3,20]],"date-time":"2018-03-20T07:01:16Z","timestamp":1521529276000},"page":"1469-1471","source":"Crossref","is-referenced-by-count":32,"title":["Dengue Fever as an Emerging Infection in Southeast Iran"],"prefix":"10.4269","volume":"98","author":[{"given":"Mostafa","family":"Heydari","sequence":"first","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, Iran;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maliheh","family":"Metanat","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, Iran;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad-Ali","family":"Rouzbeh-Far","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, Iran;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed Mehdi","family":"Tabatabaei","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, Iran;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Rakhshani","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, Iran;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nahid","family":"Sepehri-Rad","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, Iran;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Keshtkar-Jahromi","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","author":"WHO","year":"2009"},{"key":"b2","author":"WHO","year":"2013"},{"key":"b3","series-title":"WHO South-East Asia J Public Health","first-page":"24","article-title":"Current status of dengue and chikungunya in India","volume":"3","author":"Cecilia","year":"2014"},{"key":"b4","series-title":"J Infect Dev Ctries","first-page":"1176","article-title":"Serological evidence of flaviviruses infection among acute febrile illness patients in Afghanistan","volume":"8","author":"Elyan","year":"2014"},{"key":"b5","series-title":"Int J Prev Med","first-page":"1075","article-title":"First Iranian imported case of dengue","volume":"4","author":"Mardani","year":"2013"},{"key":"b6","series-title":"Travel Med Infect Dis","first-page":"166","article-title":"Preliminary study of dengue virus infection in Iran","volume":"11","author":"Chinikar","year":"2013"},{"key":"b7","series-title":"PLoS Negl Trop Dis","first-page":"e1908","article-title":"Forecast of dengue incidence using temperature and rainfall","volume":"6","author":"Hii","year":"2012"},{"key":"b8","series-title":"Rev Med Virol","article-title":"Dengue fever virus in Pakistan: effects of seasonal pattern and temperature change on distribution of vector and virus","volume":"27:","author":"Bostan","year":"2017"},{"key":"b9","series-title":"PLoS Negl Trop Dis","first-page":"e2769","article-title":"Air travel is associated with intracontinental spread of dengue virus serotypes 1\u20133 in Brazil","volume":"8","author":"Nunes","year":"2014"},{"key":"b10","series-title":"PLoS Negl Trop Dis","first-page":"e481","article-title":"The role of human movement in the transmission of vector-borne pathogens","volume":"3","author":"Stoddard","year":"2009"},{"key":"b11","series-title":"Proc Natl Acad Sci USA","first-page":"11887","article-title":"Impact of human mobility on the emergence of dengue epidemics in Pakistan","volume":"112","author":"Wesolowski","year":"2015"},{"key":"b12","series-title":"J Pak Med Assoc","first-page":"884","article-title":"Dengue viral infections in Pakistan and other Asian countries: a comprehensive review","volume":"66","author":"Zubair","year":"2016"},{"key":"b13","series-title":"Int J Infect Dis","first-page":"e518","article-title":"Seroepidemiology of dengue fever in Khyber Pakhtunkhawa, Pakistan","volume":"17","author":"Ali","year":"2013"},{"key":"b14","series-title":"Epidemiol Infect","first-page":"1525","article-title":"Detection of West Nile virus genome and specific antibodies in Iranian encephalitis patients","volume":"140","author":"Chinikar","year":"2012"},{"key":"b15","series-title":"Indian J Hematol Blood Transfus","first-page":"343","article-title":"Frequency of West Nile virus infection in Iranian blood donors","volume":"32","author":"Aghaie","year":"2016"},{"key":"b16","series-title":"Vector Borne Zoonotic Dis","first-page":"586","article-title":"Seroprevalence of West Nile virus in Iran","volume":"13","author":"Chinikar","year":"2013"},{"key":"b17","series-title":"Iran J Public Health","first-page":"1064","article-title":"Mosquito surveillance and the first record of the invasive mosquito species Aedes (Stegomyia) albopictus (Skuse) (Diptera: Culicidae) in southern Iran","volume":"45","author":"Doosti","year":"2016"},{"key":"b18","series-title":"Bull Soc Pathol Exot","first-page":"116","article-title":"Morphological studies on adult mosquitoes (Diptera: Culicidae) and first report of the potential Zika virus vector Aedes (Stegomyia) unilineatus (Theobald, 1906) in Iran","volume":"110","author":"Yaghoobi-Ershadi","year":"2017"}],"container-title":["The American Journal 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