{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:39:50Z","timestamp":1775003990906,"version":"3.50.1"},"reference-count":21,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,3,7]]},"abstract":"<jats:p><jats:italic>Taenia solium<\/jats:italic> cysticercosis is difficult to eliminate without interventions or societal development. Atahualpa is a rural Ecuadorian village with documented low migration rate, where domestic pig raising is common and human cysticercosis is endemic. To assess neurocysticercosis (NCC) prevalence, 1,273 villagers aged \u2265 20 years underwent neuroimaging studies, which showed calcified lesions in 121 (9.5%) individuals, but no active disease. Likewise, positive reactions, apparently nonspecific, were found in only 3\/200 subjects by the use of a monoclonal antibody-based enzyme-linked immunosorbent assay to detect <jats:italic>T. solium<\/jats:italic> antigens in urine. Only 2\/418 pigs reacted to three antibody bands on serum western blot and none to more than three bands. This is the first time that spontaneously arrested <jats:italic>T. solium<\/jats:italic> transmission is documented in a known endemic village. Understanding why active transmission stopped could provide insights on potential targets for control interventions. Atahualpa could provide an optimal scenario for longitudinal studies on the consequences of calcified NCC.<\/jats:p>","DOI":"10.4269\/ajtmh.17-0723","type":"journal-article","created":{"date-parts":[[2017,12,19]],"date-time":"2017-12-19T07:00:57Z","timestamp":1513666857000},"page":"776-778","source":"Crossref","is-referenced-by-count":8,"title":["Spontaneously Arrested Transmission of Cysticercosis in a Highly Endemic Village with a Very Low Migration Rate"],"prefix":"10.4269","volume":"98","author":[{"given":"Oscar H.","family":"Del Brutto","sequence":"first","affiliation":[{"name":"School of Medicine, Universidad Esp\u00edritu Santo, Ecuador, Guayaquil, Ecuador;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seth E.","family":"O\u2019Neal","sequence":"additional","affiliation":[{"name":"Center for Global Health, Universidad Peruana Cayetano Heredia, Tumbes, Per\u00fa;"},{"name":"School of Public Health, Oregon Health & Science University, Portland, Oregon;"},{"name":"Portland State University, Portland, Oregon;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Dorny","sequence":"additional","affiliation":[{"name":"Institute of Tropical Medicine, Antwerp, Belgium;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9ctor H.","family":"Garc\u00eda","sequence":"additional","affiliation":[{"name":"Center for Global Health, Universidad Peruana Cayetano Heredia, Tumbes, Per\u00fa;"},{"name":"Department of Microbiology, Universidad Peruana Cayetano Heredia, Lima, Per\u00fa;"},{"name":"Cysticercosis Unit, Instituto Nacional de Ciencias Neurol\u00f3gicas, Lima, Per\u00fa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","author":"Del Brutto","year":"2014"},{"key":"b2","series-title":"P N G Med J","first-page":"329","article-title":"Introduction of Taenia solium into west New Guinea with a note on an epidemic of burns from cysticercus 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epidemiol\u00f3gicos","volume":"26","author":"Del Brutto","year":"2017"},{"key":"b12","series-title":"Am J Trop Med Hyg","first-page":"64","article-title":"Calcified neurocysticercosis associates with hippocampal atrophy: a population-based study","volume":"91","author":"Del Brutto","year":"2015"},{"key":"b13","series-title":"Am J Trop Med Hyg","first-page":"234","article-title":"The association between neurocysticercosis and hippocampal atrophy is related to age","volume":"96","author":"Del Brutto","year":"2017"},{"key":"b14","series-title":"Epilepsia","first-page":"1955","article-title":"On the relationship between calcified neurocysticercosis and epilepsy in an endemic village: a large-scale, computed tomography-based population study in rural Ecuador","volume":"58","author":"Del Brutto","year":"2017"},{"key":"b15","series-title":"Am J Trop Med Hyg","first-page":"379","article-title":"Urine antigen detection for the diagnosis of human 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