{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T17:39:10Z","timestamp":1791999550477,"version":"4.4.0"},"reference-count":21,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,5,9]]},"abstract":"<jats:p>Given limited data on norovirus vaccine acceptance, we performed an exploratory survey in a rural Guatemalan community on knowledge, interest, and willingness to pay (WTP) for a norovirus vaccine. Cluster-randomized households with children aged 6 weeks to 17 years were enrolled into one of two norovirus surveillance studies: 1) a prospective cohort (<jats:italic>N<\/jats:italic> = 207 households) and 2) two separate, community-based, cross-sectional surveys (<jats:italic>N<\/jats:italic> = 420 households). After completion of the surveillance study, vaccine surveys were completed by 564 (90%) of 627 households. Most households correctly answered questions regarding norovirus symptoms and transmission; 97% indicated interest in a hypothetical norovirus vaccine. Households with higher education had greater WTP for a vaccine (prevalence ratios = 2.2, 95% confidence interval: 1.2\u20133.1) and households with lower WTP were more likely to use pharmacies, the Ministry of Health, and radios for health care and information. These results suggest that a future norovirus vaccination program could be acceptable and feasible even in rural areas.<\/jats:p>","DOI":"10.4269\/ajtmh.17-0771","type":"journal-article","created":{"date-parts":[[2018,3,27]],"date-time":"2018-03-27T07:00:32Z","timestamp":1522134032000},"page":"1498-1501","source":"Crossref","is-referenced-by-count":6,"title":["Knowledge of Norovirus and Attitudes toward a Potential Norovirus Vaccine in Rural Guatemala: A Cross-Sectional Exploratory Survey"],"prefix":"10.4269","volume":"98","author":[{"given":"Daniel","family":"Olson","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado;"},{"name":"Center for Global Health, Colorado School of Public Health, Aurora, Colorado;"},{"name":"Children\u2019s Hospital Colorado, Aurora, Colorado;"},{"name":"Department of Epidemiology, Colorado School of Public Health, Aurora, Colorado;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Krager","sequence":"additional","affiliation":[{"name":"Preventive Medicine Residency Program, Colorado School of Public Health, Aurora, Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Molly M.","family":"Lamb","sequence":"additional","affiliation":[{"name":"Center for Global Health, Colorado School of Public Health, Aurora, Colorado;"},{"name":"Department of Epidemiology, Colorado School of Public Health, Aurora, Colorado;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne-Marie","family":"Rick","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado;"},{"name":"Center for Global Health, Colorado School of Public Health, Aurora, Colorado;"},{"name":"Children\u2019s Hospital Colorado, Aurora, Colorado;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin J.","family":"Asturias","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado;"},{"name":"Center for Global Health, Colorado School of Public Health, Aurora, Colorado;"},{"name":"Children\u2019s Hospital Colorado, Aurora, Colorado;"},{"name":"Department of Epidemiology, Colorado School of Public Health, Aurora, Colorado;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Lancet Infect Dis","first-page":"725","article-title":"Global prevalence of norovirus in cases of gastroenteritis: a systematic review and meta-analysis","volume":"14","author":"Ahmed","year":"2014"},{"key":"b2","series-title":"PLoS One","first-page":"e0142927","article-title":"Aetiology-specific estimates of the global and regional incidence and mortality of diarrhoeal diseases commonly transmitted through food","volume":"10","author":"Pires","year":"2015"},{"key":"b3","author":"Lopman","year":"2015"},{"issue":"Suppl 5","key":"b4","series-title":"Clin Microbiol Infect","first-page":"S136","article-title":"Vaccines against norovirus: state of the art trials in children and adults","volume":"22","author":"Baehner","year":"2016"},{"key":"b5","author":"World Health Organization","year":"2014"},{"key":"b6","series-title":"Int J Public Health","first-page":"767","article-title":"Exposing concerns about vaccination in low- and middle-income countries: a systematic review","volume":"60","author":"Cobos Munoz","year":"2015"},{"key":"b7","series-title":"Vaccine","first-page":"6649","article-title":"Mapping vaccine hesitancy\u2013country-specific characteristics of a global phenomenon","volume":"32","author":"Dube","year":"2014"},{"key":"b8","series-title":"Plos Curr","article-title":"Measuring vaccine confidence: introducing a global vaccine confidence index","volume":"7","author":"Larson","year":"2015"},{"key":"b9","series-title":"Vaccine","first-page":"1719","article-title":"Use of rapid needs assessment as a tool to identify vaccination delays in Guatemala and Peru","volume":"34","author":"D\u2019Ardenne","year":"2016"},{"key":"b10","series-title":"Am J Trop Med Hyg","first-page":"419","article-title":"Sociocultural determinants of anticipated vaccine acceptance for acute watery diarrhea in early childhood in Katanga Province, Democratic Republic of Congo","volume":"89","author":"Merten","year":"2013"},{"key":"b11","series-title":"BMC Public Health","first-page":"36","article-title":"Sociocultural determinants of anticipated oral cholera vaccine acceptance in three African settings: a meta-analytic approach","volume":"16","author":"Sundaram","year":"2016"},{"key":"b12","series-title":"Open Forum Infect Dis","first-page":"ofx049","article-title":"A rapid epidemiological tool to measure the burden of norovirus infection and disease in resource-limited settings","volume":"4","author":"Olson","year":"2017"},{"key":"b13","series-title":"J Med Virol","first-page":"1293","article-title":"Prevalence and genetic diversity of norovirus among patients with acute diarrhea in Guatemala","volume":"85","author":"Estevez","year":"2013"},{"key":"b14","series-title":"Adv Pediatr","first-page":"357","article-title":"The center for human development in Guatemala: an innovative model for global population health","volume":"63","author":"Asturias","year":"2016"},{"key":"b15","series-title":"Vaccine","first-page":"4165","article-title":"Measuring vaccine hesitancy: the development of a survey tool","volume":"33","author":"Larson","year":"2015"},{"key":"b16","series-title":"Front Pharmacol","first-page":"41","article-title":"Consumer willingness to pay for dengue vaccine (CYD-TDV, Dengvaxia\u00ae) in Brazil: implications for future pricing considerations","volume":"8","author":"Godoi","year":"2017"},{"key":"b17","series-title":"Vaccine","first-page":"687","article-title":"Knowledge, attitudes, beliefs, and behaviors of parents and healthcare providers before and after implementation of a universal rotavirus vaccination program","volume":"34","author":"MacDougall","year":"2016"},{"key":"b18","series-title":"Bull World Health Organ","first-page":"554","article-title":"Reduced price on rotavirus vaccines: enough to facilitate access where most needed?","volume":"90","author":"Madsen","year":"2012"},{"key":"b19","series-title":"BMC Public Health","first-page":"834","article-title":"Social mobilisation, consent and acceptability: a review of human papillomavirus vaccination procedures in low and middle-income countries","volume":"16","author":"Kabakama","year":"2016"},{"key":"b20","series-title":"Vaccine","first-page":"5921","article-title":"Maternal knowledge, attitudes and beliefs regarding gastroenteritis and rotavirus vaccine before implementing vaccination program: which key messages in light of a new immunization program?","volume":"30","author":"Morin","year":"2012"},{"key":"b21","series-title":"Acta Paediatr","first-page":"1309","article-title":"Receiving early information and trusting Swedish child health centre nurses increased parents\u2019 willingness to vaccinate against rotavirus infections","volume":"106","author":"Schollin Ask","year":"2017"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/98\/5\/article-p1498.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/98\/5\/article-p1498.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/98\/5\/article-p1498.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T17:11:42Z","timestamp":1722445902000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/98\/5\/article-p1498.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,9]]},"references-count":21,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.17-0771","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,9]]}}}