{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T17:39:53Z","timestamp":1793295593890,"version":"4.5.0"},"reference-count":16,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,5,9]]},"abstract":"<jats:p><jats:italic>Burkholderia pseudomallei<\/jats:italic>, the etiologic agent of melioidosis, is an important but under-recognized cause of disease in the tropics. Although first described over a century ago as a septicemic illness associated with morphine addicts in Rangoon, Burma, there is little information regarding the incidence of melioidosis in present-day Myanmar. To address this issue, we used two recently developed and validated serological assays to detect <jats:italic>B. pseudomallei<\/jats:italic>\u2013specific antibodies in 124 serum samples obtained from febrile patients in the delta region of Myanmar. Using cutoff values derived from culture-confirmed melioidosis cases in neighboring Thailand, 3.2% of the samples exhibited reactivity profiles consistent with active <jats:italic>B. pseudomallei<\/jats:italic> infections. Collectively, these findings indicate that melioidosis likely represents a significant cause of morbidity and mortality in Myanmar and support the need for further studies to assess the true burden of disease in this country.<\/jats:p>","DOI":"10.4269\/ajtmh.17-0791","type":"journal-article","created":{"date-parts":[[2018,3,20]],"date-time":"2018-03-20T07:01:11Z","timestamp":1521529271000},"page":"1300-1302","source":"Crossref","is-referenced-by-count":11,"title":["Use of Rapid Enzyme-Linked Immunosorbent Assays for Serological Screening of Melioidosis in Myanmar"],"prefix":"10.4269","volume":"98","author":[{"given":"Zin Zayar","family":"Win","sequence":"first","affiliation":[{"name":"Biomedical Research Division, Nay Pyi Taw, Myanmar;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phornpun","family":"Phokrai","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zarni","family":"Aung","sequence":"additional","affiliation":[{"name":"Biomedical Research Division, Nay Pyi Taw, Myanmar;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thein","family":"Zaw","sequence":"additional","affiliation":[{"name":"Biomedical Research Division, Nay Pyi Taw, Myanmar;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary N.","family":"Burtnick","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, University of Nevada, Reno School of Medicine, Reno, Nevada;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narisara","family":"Chantratita","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand;"},{"name":"Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Brett","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, University of Nevada, Reno School of Medicine, Reno, Nevada;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tin Maung","family":"Hlaing","sequence":"additional","affiliation":[{"name":"Defence Services Medical Research Centre, Nay Pyi Taw, Myanmar"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"PLoS Negl Trop Dis","first-page":"e2072","article-title":"Activities of daily living associated with acquisition of melioidosis in northeast Thailand: a matched case-control study","volume":"7","author":"Limmathurotsakul","year":"2013"},{"key":"b2","series-title":"Trop Med Int Health","first-page":"1167","article-title":"Melioidosis epidemiology and risk factors from a prospective whole-population study in northern 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