{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T19:24:27Z","timestamp":1745004267970},"reference-count":19,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,11,7]]},"abstract":"<jats:p>We sought to compare seroprevalence of protective measles and rubella-specific antibody in mother\u2013infant pairs across two populations: a pre-disease elimination Nepal population with recently introduced rubella vaccine and post-disease elimination U.S. population. Qualitative measles and rubella immunoglobulin G was assessed in maternal serum and cord blood from 258 pairs in Nepal, 2012\u20132013 and 49 pairs in Seattle, WA, 2014\u20132015. High rates of protective antibody were observed in both populations. Two hundred and forty-four (95%) pregnant women in Nepal had protective measles antibody versus 44 (92%) in Seattle (<jats:italic>P<\/jats:italic> = 0.42). Ninety-six percent of infants in Nepal (<jats:italic>N<\/jats:italic> = 246) and Seattle (<jats:italic>N<\/jats:italic> = 43) had protective measles antibody (<jats:italic>P<\/jats:italic> = 0.75). Ninety-four percentage of pregnant women in Nepal (<jats:italic>N<\/jats:italic> = 242) and Seattle (<jats:italic>N<\/jats:italic> = 45) had protective rubella antibody (<jats:italic>P<\/jats:italic> = 0.23). Two hundred and thirty-eight (93%) infants in Nepal had protective rubella antibody versus 44 (98%) in Seattle (<jats:italic>P<\/jats:italic> = 0.12). Continued surveillance will be necessary to ensure protective immunity, inform progress toward disease elimination in Nepal and avoid reemergence in the United States.<\/jats:p>","DOI":"10.4269\/ajtmh.17-0836","type":"journal-article","created":{"date-parts":[[2018,9,18]],"date-time":"2018-09-18T07:01:00Z","timestamp":1537254060000},"page":"1342-1345","source":"Crossref","is-referenced-by-count":5,"title":["Measles and Rubella Seroprevalence in Mother\u2013Infant Pairs in Rural Nepal and the United States: Pre- and Post-Elimination Populations"],"prefix":"10.4269","volume":"99","author":[{"given":"Alastair F.","family":"Murray","sequence":"first","affiliation":[{"name":"George Washington University School of Medicine & Health Sciences, Washington, District of Columbia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet A.","family":"Englund","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Seattle Children\u2019s Hospital, University of Washington, Seattle, Washington;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James M.","family":"Tielsch","sequence":"additional","affiliation":[{"name":"Department of Global Health, Milken Institute School of Public Health, George Washington University, Washington, District of Columbia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanne","family":"Katz","sequence":"additional","affiliation":[{"name":"Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laxman","family":"Shrestha","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health, Nepal Institute of Medicine, Kathmandu,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subarna K.","family":"Khatry","sequence":"additional","affiliation":[{"name":"Nepal Nutrition Intervention Project\u2014Sarlahi (NNIPS), Kathmandu, Nepal;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristen","family":"Carlin","sequence":"additional","affiliation":[{"name":"Children\u2019s Core for Biomedical Statistics, Seattle Children\u2019s Research Institute, Seattle, Washington;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven C.","family":"Leclerq","sequence":"additional","affiliation":[{"name":"Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark C.","family":"Steinhoff","sequence":"additional","affiliation":[{"name":"Global Health Center, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen Y.","family":"Chu","sequence":"additional","affiliation":[{"name":"Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Clin Infect Dis","first-page":"226","article-title":"Subacute sclerosing panencephalitis: the devastating measles complication that might be more common than previously estimated","volume":"65","author":"Wendorf","year":"2017"},{"key":"b2","series-title":"Wkly Epidemiol Rec","first-page":"205","article-title":"Measles vaccines: WHO position paper\u2014April 2017","volume":"92","author":"World Health Organization","year":"2017"},{"key":"b3","series-title":"Wkly Epidemiol Rec","first-page":"301","article-title":"Rubella vaccines: WHO position paper\u2014July 2011","volume":"86","author":"World Health Organization","year":"2011"},{"key":"b4","series-title":"Vaccine","first-page":"7057","article-title":"Safety of immunization during pregnancy: a review of the evidence, Global Advisory Committee on Vaccine Safety","volume":"32","author":"Keller-Stanislawski","year":"2014"},{"key":"b5","series-title":"J Pediatric Infect Dis Soc","first-page":"40","article-title":"A comparison of postelimination measles epidemiology in the United States, 2009\u20132014 versus 2001\u20132008","volume":"6","author":"Fiebelkorn","year":"2017"},{"key":"b6","series-title":"MMWR Morb Mortal Wkly Rep","first-page":"153","article-title":"Measles outbreak\u2014California, December 2014\u2013February 2015","volume":"64","author":"Zipprich","year":"2015"},{"key":"b7","series-title":"MMWR Morb Mortal Wkly Rep","first-page":"713","article-title":"Measles outbreak\u2014Minnesota April\u2013May 2017","volume":"66","author":"Hall","year":"2017"},{"year":"2017","author":"Centers for Disease Control and Prevention","key":"b8"},{"year":"2012","author":"World Health Organization","key":"b9"},{"key":"b10","series-title":"MMWR Morb Mortal Wkly Rep","first-page":"206","article-title":"Progress toward measles 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