{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T06:08:21Z","timestamp":1783577301792,"version":"3.55.0"},"reference-count":34,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,6,6]]},"abstract":"<jats:p>The ongoing Zika pandemic has affected many countries that are common travel destinations. We assessed the willingness to receive a prophylactic Zika virus (ZIKV) vaccine, currently under development, among travelers to areas with reported autochthonous ZIKV transmission. We surveyed United States (U.S.) residents aged 18\u201344 years who had ever heard of ZIKV and planned to travel to Florida and\/or Texas (<jats:italic>N<\/jats:italic> = 420) or a U.S. territory or foreign country (<jats:italic>N<\/jats:italic> = 415) in 2017, using a nationally representative internet panel. Travelers to Florida and\/or Texas reported less concern about ZIKV infection than travelers to other destinations (27% versus 36%, <jats:italic>P<\/jats:italic> = 0.01). Female sex, Hispanic ethnicity, discussing ZIKV with medical professionals, ZIKV risk perception, and self-efficacy for ZIKV prevention predicted concern about ZIKV infection in both groups. Travelers to Florida and\/or Texas (43%) and other destinations (44%) were equally willing to receive a ZIKV vaccine. Hispanic ethnicity, discussing ZIKV with medical professionals, and concern about ZIKV infection predicted vaccine willingness in both groups. Likelihood of using existing ZIKV prevention methods, confidence in the U.S. government to prevent ZIKV spread, self-efficacy for ZIKV prevention, and knowledge about ZIKV symptoms further predicted vaccine willingness in travelers to other destinations. In multivariable analyses, only concern about ZIKV infection was associated with vaccine willingness in both groups (prevalence ratio [95% confidence interval]: Florida and\/or Texas: 1.34 [1.06, 1.69]; other: 1.82 [1.44, 2.29]). Targeted communications can educate travelers, particularly travelers who are pregnant or may become pregnant, about ZIKV risk to generate ZIKV vaccine demand.<\/jats:p>","DOI":"10.4269\/ajtmh.17-0907","type":"journal-article","created":{"date-parts":[[2018,4,24]],"date-time":"2018-04-24T07:00:34Z","timestamp":1524553234000},"page":"1848-1856","source":"Crossref","is-referenced-by-count":11,"title":["United States Travelers\u2019 Concern about Zika Infection and Willingness to Receive a Hypothetical Zika Vaccine"],"prefix":"10.4269","volume":"98","author":[{"given":"Nadja A.","family":"Vielot","sequence":"first","affiliation":[{"name":"Department of Family Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lola","family":"Stamm","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, UNC Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Herrington","sequence":"additional","affiliation":[{"name":"Department of Health Behavior, UNC Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Squiers","sequence":"additional","affiliation":[{"name":"RTI International, Research Triangle Park, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bridget","family":"Kelly","sequence":"additional","affiliation":[{"name":"RTI International, Research Triangle Park, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"McCormack","sequence":"additional","affiliation":[{"name":"RTI International, Research Triangle Park, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvia","family":"Becker-Dreps","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina;"},{"name":"Department of Epidemiology, UNC Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","author":"Centers for Disease Control and Prevention","year":"2017"},{"key":"b2","author":"International Trade Administration","year":"2015"},{"key":"b3","series-title":"N Engl J Med","first-page":"2536","article-title":"Zika virus outbreak on Yap Island, Federated States of Micronesia","volume":"360","author":"Duffy","year":"2009"},{"key":"b4","series-title":"Lancet","first-page":"891","article-title":"Congenital Zika virus syndrome in Brazil: a case series of the first 1501 livebirths with complete investigation","volume":"388","author":"Fran\u00e7a","year":"2016"},{"key":"b5","series-title":"JAMA Pediatr","first-page":"288","article-title":"Characterizing the pattern of anomalies in congenital Zika syndrome for pediatric clinicians","volume":"171","author":"Moore","year":"2017"},{"key":"b6","series-title":"Science","first-page":"816","article-title":"Zika virus impairs growth in human neurospheres and brain organoids","volume":"352","author":"Garcez","year":"2016"},{"key":"b7","series-title":"N Engl J Med","first-page":"1598","article-title":"Zika virus and the Guillain\u2013Barr\u00e9 syndrome\u2014case series from seven countries","volume":"375","author":"dos Santos","year":"2016"},{"key":"b8","author":"Centers for Disease Control and Prevention","year":"2016"},{"key":"b9","author":"Centers for Disease Control and Prevention","year":"2017"},{"key":"b10","series-title":"JAMA","first-page":"691","article-title":"Emerging and reemerging infectious diseases: the dichotomy between acute outbreaks and chronic endemicity","volume":"317","author":"Paules","year":"2017"},{"key":"b11","series-title":"Cell","first-page":"273","article-title":"Vaccine mediated protection against Zika virus-induced congenital disease","volume":"170","author":"Richner","year":"2017"},{"key":"b12","series-title":"Nat Med","first-page":"763","article-title":"A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models","volume":"23","author":"Shan","year":"2017"},{"key":"b13","series-title":"Science","first-page":"1129","article-title":"Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys","volume":"353","author":"Abbink","year":"2016"},{"key":"b14","series-title":"Clin Ther","first-page":"1519","article-title":"Progress and works in progress: update on flavivirus vaccine development","volume":"39","author":"Collins","year":"2017"},{"key":"b15","series-title":"Nature","first-page":"474","article-title":"Vaccine protection against Zika virus from Brazil","volume":"536","author":"Larocca","year":"2016"},{"key":"b16","series-title":"Immunity","first-page":"176","article-title":"Prospects for a Zika virus vaccine","volume":"46","author":"Barouch","year":"2017"},{"key":"b17","author":"GfK","year":"2017"},{"key":"b18","series-title":"Am J Trop Med Hyg","first-page":"1837","article-title":"ZIKV prevention: United States travelers\u2019 knowledge, risk perceptions, and behavioral intentions\u2014a national survey","volume":"98","author":"Squiers","year":"2018"},{"key":"b19","author":"United States Census Bureau","year":"2015"},{"key":"b20","author":"Centers for Disease Control and Prevention","year":"2017"},{"key":"b21","series-title":"Neonatology","first-page":"177","article-title":"Is there more to Zika? Complex cardiac disease in a case of congenital Zika syndrome","volume":"113","author":"Angelidou","year":"2017"},{"key":"b22","series-title":"MMWR Morb Mortal Wkly Rep","first-page":"1347","article-title":"Health and development at age 19\u201324 months of 19 children who were born with microcephaly and laboratory evidence of congenital Zika virus infection during the 2015 Zika virus outbreak\u2014Brazil, 2017","volume":"66","author":"Satterfield-Nash","year":"2017"},{"key":"b23","series-title":"JAMA Pediatr","first-page":"478","article-title":"Bridging knowledge gaps to understand how Zika virus exposure and infection affect child development","volume":"171","author":"Kapogiannis","year":"2017"},{"key":"b24","author":"Boer","year":"1996"},{"key":"b25","series-title":"J Community Health","first-page":"854","article-title":"Differences in perceived severity of Zika virus infection and dengue fever and its influence on mosquito control practices in Malaysia","volume":"42","author":"Wong","year":"2017"},{"key":"b26","series-title":"J Health Commun","first-page":"278","article-title":"The 2009 H1N1 influenza pandemic: the role of threat, coping, and media trust on vaccination intentions in Canada","volume":"18","author":"Taha","year":"2013"},{"key":"b27","series-title":"Health Psychol","first-page":"82","article-title":"Emotions and preventive health behavior: worry, regret, and influenza vaccination","volume":"25","author":"Chapman","year":"2006"},{"key":"b28","series-title":"Vaccine","first-page":"4084","article-title":"How do anticipated worry and regret predict seasonal influenza vaccination uptake among Chinese adults?","volume":"31","author":"Liao","year":"2013"},{"key":"b29","series-title":"JAMA","first-page":"2856","article-title":"Travel medicine considerations for North American immgrants visiting friends and relatives","volume":"291","author":"Bacaner","year":"2004"},{"key":"b30","series-title":"Malar J","first-page":"287","article-title":"\u201cYou\u2019re losing your Ghanaianess\u201d: understanding malaria decision-making among Africans visiting friends and relatives in the UK","volume":"13","author":"Neave","year":"2014"},{"key":"b31","series-title":"Vaccine","first-page":"5912","article-title":"Attitudes towards Zika screening and vaccination acceptability among pregnant women in Malaysia","volume":"35","author":"Wong","year":"2017"},{"key":"b32","series-title":"BMC Pregnancy Childbirth","first-page":"1","article-title":"A survey-based study of Zika virus communication preferences among pregnant women in Georgia, United States","volume":"17","author":"Ellingson","year":"2017"},{"key":"b33","series-title":"N Engl J Med","first-page":"843","article-title":"Declines in unintended pregnancy in the United States, 2008\u20132011","volume":"374","author":"Finer","year":"2016"},{"key":"b34","series-title":"J Clin Psychol Med Settings","first-page":"270","article-title":"Psychological predictors of health anxiety in response to the Zika virus","volume":"24","author":"Blakey","year":"2017"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/98\/6\/article-p1848.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/98\/6\/article-p1848.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/98\/6\/article-p1848.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T17:54:59Z","timestamp":1722448499000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/98\/6\/article-p1848.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,6]]},"references-count":34,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.17-0907","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,6]]}}}