{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T14:52:00Z","timestamp":1780930320570,"version":"3.54.1"},"reference-count":24,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,7,5]]},"abstract":"<jats:p>Cystic echinococcosis (CE) is a globally endemic zoonosis caused by the larval stage of the <jats:italic>Echinococcus granulosus<\/jats:italic> sensu lato (s.l.) complex. Although the disease is known to be highly prevalent in certain parts of North and East Africa, data on CE, both in humans and definitive hosts, are extremely scarce for Central Africa. The present study assessed the epidemiology of CE in humans and dogs in rural Gabon. An ultrasound and serologic survey was conducted in volunteers from rural villages in Gabon. A two-step approach was used for serological testing with an indirect hemagglutination assay as a screening test and Western Blot as a confirmatory test. Fecal dog samples were analyzed microscopically, and polymerase chain reaction (PCR) amplification of <jats:italic>nad1<\/jats:italic> and <jats:italic>cox1<\/jats:italic> genes was performed when taeniid eggs were visible. Regional hospitals and the national reference center for parasitology in Gabon were contacted for information about previous cases of CE. Randomly selected communities were invited to participate. Three hundred and forty-eight human volunteers from these communities were screened. No suspected cases of CE were detected. Definitive host screening was performed from 128 fecal samples from representative subregions, but no eggs from <jats:italic>E. granulosus<\/jats:italic> s.l. were found. No documented cases of echinococcosis were reported from the local health-care institutions and the national diagnostic reference center in Gabon. Cystic echinococcosis seems to be very rare or absent in Gabon. The reason for this lack of evidence for echinococcosis is unknown, but the absence of livestock may play a major role.<\/jats:p>","DOI":"10.4269\/ajtmh.17-0955","type":"journal-article","created":{"date-parts":[[2018,5,22]],"date-time":"2018-05-22T07:00:22Z","timestamp":1526972422000},"page":"97-101","source":"Crossref","is-referenced-by-count":5,"title":["Preliminary Evidence for the Absence of Cystic Echinococcosis in Gabon: A Cross-Sectional Pilot Survey in Humans and Definitive Hosts"],"prefix":"10.4269","volume":"99","author":[{"given":"Felix","family":"L\u00f6tsch","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University of Vienna, Vienna, Austria;"},{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambar\u00e9n\u00e9, Gabon;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghyslain","family":"Mombo-Ngoma","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambar\u00e9n\u00e9, Gabon;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Mischlinger","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University of Vienna, Vienna, Austria;"},{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambar\u00e9n\u00e9, Gabon;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirjam","family":"Groger","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University of Vienna, Vienna, Austria;"},{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambar\u00e9n\u00e9, Gabon;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luzia","family":"Veletzky","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University of Vienna, Vienna, Austria;"},{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambar\u00e9n\u00e9, Gabon;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u00f4la Akim","family":"Adegnika","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambar\u00e9n\u00e9, Gabon;"},{"name":"Institut f\u00fcr Tropenmedizin, Universit\u00e4t T\u00fcbingen, T\u00fcbingen, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Lell","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambar\u00e9n\u00e9, Gabon;"},{"name":"Institut f\u00fcr Tropenmedizin, Universit\u00e4t T\u00fcbingen, T\u00fcbingen, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selidji Todagbe","family":"Agnandji","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambar\u00e9n\u00e9, Gabon;"},{"name":"Institut f\u00fcr Tropenmedizin, Universit\u00e4t T\u00fcbingen, T\u00fcbingen, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marielle","family":"Bouyou-Akotet","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Parasitologie-Mycologie M\u00e9decine Tropicale, Facult\u00e9 de M\u00e9decine, Universit\u00e9 des Sciences de la Sant\u00e9, Libreville, Gabon;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Oberm\u00fcller","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University of Vienna, Vienna, Austria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Wassermann","sequence":"additional","affiliation":[{"name":"Department of Parasitology, University of Hohenheim, Stuttgart, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renate","family":"Schneider","sequence":"additional","affiliation":[{"name":"Department of Medical Parasitology, Institute of Specific Prophylaxis and Tropical Medicine, Center of Pathophysiology, Infectiology and Immunology, Medical University Vienna, Vienna, Austria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert","family":"Auer","sequence":"additional","affiliation":[{"name":"Department of Medical Parasitology, Institute of Specific Prophylaxis and Tropical Medicine, Center of Pathophysiology, Infectiology and Immunology, Medical University Vienna, Vienna, Austria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Ramharter","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University of Vienna, Vienna, Austria;"},{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambar\u00e9n\u00e9, Gabon;"},{"name":"Institut f\u00fcr Tropenmedizin, Universit\u00e4t T\u00fcbingen, T\u00fcbingen, Germany;"},{"name":"Department of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Centre, Hamburg-Eppendorf, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Lancet Infect Dis","first-page":"871","article-title":"Cystic echinococcosis in sub-Saharan Africa","volume":"12","author":"Wahlers","year":"2012"},{"key":"b2","series-title":"Vet Parasitol","first-page":"43","article-title":"Echinococcosis in sub-Saharan Africa: emerging complexity","volume":"181","author":"Romig","year":"2011"},{"key":"b3","series-title":"Adv Parasitol","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/bs.apar.2016.11.001","article-title":"Global distribution of alveolar and cystic echinococcosis","volume":"95","author":"Deplazes","year":"2017"},{"key":"b4","series-title":"Ann Trop Med Parasitol","first-page":"601","article-title":"Canine echinococcosis in Turkana (north\u2013western Kenya): a coproantigen survey in the previous hydatid-control area and an analysis of risk factors","volume":"100","author":"Buishi","year":"2006"},{"key":"b5","series-title":"Vet Parasitol","first-page":"223","article-title":"Canine echinococcosis in northwest Libya: assessment of coproantigen ELISA, and a survey of infection with analysis of risk-factors","volume":"130","author":"Buishi","year":"2005"},{"key":"b6","series-title":"Ann Trop Med Parasitol","first-page":"51","article-title":"Hydatid disease in the Turkana District of Kenya, IV. 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