{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T19:25:25Z","timestamp":1790364325026,"version":"4.1.0"},"reference-count":43,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,9,5]]},"abstract":"<jats:p>A retrospective study was conducted to identify the risk factors associated with <jats:italic>Salmonella enterica<\/jats:italic> bacteremia in infants and children in Guadeloupe, French West Indies. The 171 patients with <jats:italic>S. enterica<\/jats:italic> infection seen between 2010 and 2014 included 155 (90.6%) with acute gastroenteritis, of whom 42 (27.1%) had concomitant bacteremia, and 16 (9.4%) with primary bacteremia. Most cases (97.7%) were in infants and children with no underlying health condition. Two subspecies were recovered: <jats:italic>enterica<\/jats:italic> (<jats:italic>N<\/jats:italic> = 161, 94.2%) and <jats:italic>houtenae<\/jats:italic> (<jats:italic>N<\/jats:italic> = 10, 5.8%). All but one (serovar Typhi) were non-typhoidal <jats:italic>Salmonella<\/jats:italic>. The most common serovars were Panama (<jats:italic>N<\/jats:italic> = 57, 33.3% of isolates) and Arechavaleta (<jats:italic>N<\/jats:italic> = 28, 16.4%). Univariate analysis showed a strong association only between age &gt; 6 months and infection with the Panama or Arechavaleta serovar (<jats:italic>P<\/jats:italic> = 0.002). The rate of resistance to all classes of antibiotics during the study period was low (&lt; 15%); however, the detection of one extended-spectrum beta-lactamase\u2013producing <jats:italic>S. enterica<\/jats:italic> strain highlights the need for continued monitoring of antimicrobial drug susceptibility. Infection with Panama (<jats:italic>P<\/jats:italic> &lt; 0.001) or Arechavaleta (<jats:italic>P<\/jats:italic> &lt; 0.001) serovar was significantly associated with bacteremia in a multivariate analysis. These serovars are probably poorly adapted to humans or are more virulent. A delay between onset of symptoms and hospital admission &gt; 5 days (<jats:italic>P<\/jats:italic> = 0.01), vomiting (<jats:italic>P<\/jats:italic> = 0.001), and increased respiratory rate (<jats:italic>P<\/jats:italic> = 0.001) contributed independently to bacteremia in the multivariate analysis. Thus, if non-typhoidal infection is suspected, blood should be cultured and antibiotic treatment initiated in all patients who meet these criteria.<\/jats:p>","DOI":"10.4269\/ajtmh.18-0192","type":"journal-article","created":{"date-parts":[[2018,7,17]],"date-time":"2018-07-17T07:00:29Z","timestamp":1531810829000},"page":"584-589","source":"Crossref","is-referenced-by-count":7,"title":["Salmonella enterica serovars Panama and Arechavaleta: Risk Factors for Invasive Non-Typhoidal Salmonella Disease in Guadeloupe, French West Indies"],"prefix":"10.4269","volume":"99","author":[{"given":"Stephanie","family":"Guyomard-Rabenirina","sequence":"first","affiliation":[{"name":"Unit\u00e9 Environnement et Sant\u00e9, Institut Pasteur de Guadeloupe, Pointe-\u00e0-Pitre, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blandine","family":"Muanza","sequence":"additional","affiliation":[{"name":"Service de P\u00e9diatrie, Centre Hospitalier Universitaire de Pointe-\u00e0-Pitre\/les Abymes, Pointe-\u00e0-Pitre, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvaine","family":"Bastian","sequence":"additional","affiliation":[{"name":"Laboratoire de Microbiologie Clinique et Environnementale, Centre Hospitalier Universitaire de Pointe-\u00e0-Pitre\/les Abymes, Pointe-\u00e0-Pitre, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edith","family":"Malpote","sequence":"additional","affiliation":[{"name":"Laboratoire de Microbiologie Clinique et Environnementale, Centre Hospitalier Universitaire de Pointe-\u00e0-Pitre\/les Abymes, Pointe-\u00e0-Pitre, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline","family":"Jestin","sequence":"additional","affiliation":[{"name":"Laboratoire de Microbiologie Clinique et Environnementale, Centre Hospitalier Universitaire de Pointe-\u00e0-Pitre\/les Abymes, Pointe-\u00e0-Pitre, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meggie","family":"Guerin","sequence":"additional","affiliation":[{"name":"Laboratoire de Microbiologie Clinique et Environnementale, Centre Hospitalier Universitaire de Pointe-\u00e0-Pitre\/les Abymes, Pointe-\u00e0-Pitre, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Talarmin","sequence":"additional","affiliation":[{"name":"Unit\u00e9 Environnement et Sant\u00e9, Institut Pasteur de Guadeloupe, Pointe-\u00e0-Pitre, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois-Xavier","family":"Weill","sequence":"additional","affiliation":[{"name":"Unit\u00e9 des Bact\u00e9ries Pathog\u00e8nes Ent\u00e9riques, Centre National de R\u00e9f\u00e9rence des Escherichia coli, Shigella et Salmonella, Institut Pasteur, Paris, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaud","family":"Legrand","sequence":"additional","affiliation":[{"name":"Direction de la Recherche Clinique et de L\u2019innovation, Centre Hospitalier Universitaire de Nantes, Nantes, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastien","family":"Breurec","sequence":"additional","affiliation":[{"name":"Unit\u00e9 Environnement et Sant\u00e9, Institut Pasteur de Guadeloupe, Pointe-\u00e0-Pitre, France;"},{"name":"Unit\u00e9 des Bact\u00e9ries Pathog\u00e8nes Ent\u00e9riques, Centre National de R\u00e9f\u00e9rence des Escherichia coli, Shigella et Salmonella, Institut Pasteur, Paris, France;"},{"name":"Facult\u00e9 de M\u00e9decine Hyacinthe Bastaraud, Universit\u00e9 des Antilles, Pointe-\u00e0-Pitre, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Clin Microbiol 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