{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T21:10:33Z","timestamp":1722460233335},"reference-count":21,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,12,5]]},"abstract":"<jats:p>Visceral larva migrans (VLM) is one of the clinical syndromes of human toxocariasis. We report a case of hepatic VLM presenting preprandial malaise and epigastric discomfort in a 58-year-old woman drinking raw roe deer blood. The imaging studies of the abdomen showed a 74-mm hepatic mass featuring hepatic VLM. Anti\u2013<jats:italic>Toxocara canis<\/jats:italic> immunoglobulin G (IgG) was observed in enzyme-linked immunosorbent assay (ELISA) and western blot. Despite anthelmintic treatment, the patient complained of newly developed cough and skin rash with severe eosinophilia. Hepatic lesion increased in size. The patient underwent an open left lobectomy of the liver. After the surgery, the patient was free of symptoms such as preprandial malaise, epigastric discomfort, cough, and skin rash. Laboratory test showed a normal eosinophilic count at postoperative 1 month, 6 months, 1 year, and 4 years. The initial optical density value of 2.55 of anti\u2013<jats:italic>T. canis<\/jats:italic> IgG in ELISA was found to be negative (0.684) at postoperative 21 months. Our case report highlights that a high degree of clinical suspicion for hepatic VLM should be considered in a patient with a history of ingestion of raw food in the past, presenting severe eosinophilia and a variety of symptoms which reflect high worm burdens. Symptom remission, eosinophilia remission, and complete radiological resolution of lesions can be complete with surgery.<\/jats:p>","DOI":"10.4269\/ajtmh.18-0199","type":"journal-article","created":{"date-parts":[[2018,10,2]],"date-time":"2018-10-02T07:00:25Z","timestamp":1538463625000},"page":"1602-1605","source":"Crossref","is-referenced-by-count":3,"title":["Space Occupying Lesion in the Liver Caused by Hepatic Visceral Larva Migrans: A Case Report"],"prefix":"10.4269","volume":"99","author":[{"given":"Kye-Yeung","family":"Park","sequence":"first","affiliation":[{"name":"Department of Family Medicine, Hanyang University College of Medicine, Seoul, Korea;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hoon-Ki","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, Hanyang University College of Medicine, Seoul, Korea;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hwan-Sik","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, Hanyang University College of Medicine, Seoul, Korea;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae-Sook","family":"Ryu","sequence":"additional","affiliation":[{"name":"Department of Environmental Biology and Medical Parasitology, Hanyang University College of Medicine, Seoul, Korea;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyeong-Geun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hanyang University College of Medicine, Seoul, Korea;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ki-Seok","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Pathology Hanyang University College of Medicine, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Ann Trop Med Parasitol","first-page":"3","article-title":"Human toxocariasis: diagnosis, worldwide seroprevalences and clinical expression of the systemic and ocular forms","volume":"104","author":"Rubinsky-Elefant","year":"2010"},{"key":"b2","series-title":"Lancet","first-page":"692","article-title":"The expanded spectrum of toxocaral disease","volume":"1","author":"Taylor","year":"1988"},{"key":"b3","series-title":"J Korean Med Sci","first-page":"1","article-title":"Foodborne eosinophilia due to visceral larva migrans: a disease abandoned","volume":"27","author":"Lim","year":"2012"},{"key":"b4","series-title":"J Helminthol","first-page":"299","article-title":"Toxocariasis in humans: clinical expression and treatment dilemma","volume":"75","author":"Pawlowski","year":"2001"},{"key":"b5","series-title":"Trends Parasitol","first-page":"182","article-title":"How common is human toxocariasis? 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