{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T01:19:58Z","timestamp":1793582398828,"version":"4.5.0"},"reference-count":29,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,10,3]]},"abstract":"<jats:p>Taeniasis\/cysticercosis (CC) is an important disease complex with significant burden. This large-scale cohort study aimed at estimating and exploring individual- and village-level factors associated with the cumulative incidences of seroconversion (SC) and seroreversion (SR) of active human CC in three provinces of Burkina Faso. In 60 villages, blood samples were collected and interviews regarding sociodemographic variables and knowledge, attitude, and practices toward the disease complex were conducted at baseline and 18-month follow-up (<jats:italic>N<\/jats:italic> = 2,211), with the presence of active CC being determined using the B158\/B60 antigen enzyme-linked immunosorbent assay (Ag-ELISA). The 18-month Ag SC and SR were estimated at 3.3% (95% confidence interval [CI]: 2.6; 4.2%) and 35.8% (95% CI: 24.5; 48.5%), respectively. Marked provincial differences were found for the 18-month Ag SC (Boulkiemde: cumulative incidence ratio [CIR]: 2.41 (95% CI: 1.21; 4.78) and Nayala: CIR: 3.28 (95% CI: 1.37; 7.84), compared with Sanguie), while not being significantly associated with other sociodemographic factors. A continued refraining from pork consumption was associated with a lower 18-month Ag SC (CIR: 0.55 [95% CI: 0.28; 1.07]), whereas at the village level, the percentage of households owning pigs was associated with a higher 18-month Ag SC (CIR: 1.03 [95% CI: 1.01; 1.05]). In conclusion, this is one of few cohort studies and the first to have enough power to assess possible causal links between individual- and village-level variables and CC in humans. Variables linked to province, pig raising, and pork consumption behaviors were found to cause Ag SC in humans. The latter results further support the importance of adopting a One Health approach to the control of CC.<\/jats:p>","DOI":"10.4269\/ajtmh.18-0294","type":"journal-article","created":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T07:02:33Z","timestamp":1536130953000},"page":"1018-1027","source":"Crossref","is-referenced-by-count":16,"title":["Factors Associated with the 18-Month Cumulative Incidence of Seroconversion of Active Infection with Taenia solium Cysticercosis: A Cohort Study among Residents of 60 Villages in Burkina Faso"],"prefix":"10.4269","volume":"99","author":[{"given":"Veronique","family":"Dermauw","sequence":"first","affiliation":[{"name":"Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Carabin","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasman\u00e9","family":"Ganaba","sequence":"additional","affiliation":[{"name":"Agence de Formation de Recherche et d\u2019Expertise en Sant\u00e9 pour l\u2019Afrique (AFRICSant\u00e9), Bobo Dioulasso, Burkina Faso;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Assana","family":"Ciss\u00e9","sequence":"additional","affiliation":[{"name":"Institut de Recherche en Sciences de la Sant\u00e9, Bobo Dioulasso, Burkina Faso;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z\u00e9kiba","family":"Tarnagda","sequence":"additional","affiliation":[{"name":"Institut de Recherche en Sciences de la Sant\u00e9, Bobo Dioulasso, Burkina Faso;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Gabri\u00ebl","sequence":"additional","affiliation":[{"name":"Department of Veterinary Public Health and Food Safety, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Dorny","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium;"},{"name":"Laboratory of Veterinary Parasitology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athanase","family":"Millogo","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire Souro Sanou, Bobo Dioulasso, Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"PLoS Negl Trop Dis","first-page":"e406","article-title":"The disease burden of Taenia solium cysticercosis in Cameroon","volume":"3","author":"Praet","year":"2009"},{"key":"b2","series-title":"Trop Med Int Health","first-page":"906","article-title":"Estimation of the cost of Taenia solium cysticercosis in Eastern Cape province, South Africa","volume":"11","author":"Carabin","year":"2006"},{"key":"b3","series-title":"PLoS Negl Trop Dis","first-page":"e1521","article-title":"Estimating the non-monetary burden of neurocysticercosis in Mexico","volume":"6","author":"Bhattarai","year":"2012"},{"key":"b4","series-title":"PLoS Med","first-page":"e1001920","article-title":"World Health Organization estimates of the global and regional disease burden of 11 foodborne parasitic diseases, 2010: a data synthesis","volume":"12","author":"Torgerson","year":"2015"},{"key":"b5","series-title":"BMC Infect Dis","first-page":"127","article-title":"Assessment of the societal cost of Taenia solium in Ang\u00f3nia district, Mozambique","volume":"18","author":"Trevisan","year":"2018"},{"key":"b6","series-title":"Am J Trop Med Hyg","first-page":"354","article-title":"Cysticercosis-related hospitalizations in the United States, 1998\u20132011","volume":"92","author":"O\u2019Keefe","year":"2015"},{"key":"b7","series-title":"PLoS Negl Trop Dis","first-page":"e1152","article-title":"Clinical manifestations associated with neurocysticercosis: a systematic review","volume":"5","author":"Carabin","year":"2011"},{"key":"b8","series-title":"PLoS Med","first-page":"e1001923","article-title":"World Health Organization global estimates and regional comparisons of the burden of foodborne disease in 2010","volume":"12","author":"Havelaar","year":"2015"},{"key":"b9","series-title":"PLoS Negl Trop Dis","first-page":"e0004248","article-title":"Prevalence of and factors associated with human cysticercosis in 60 villages in three provinces of Burkina Faso","volume":"9","author":"Carabin","year":"2015"},{"key":"b10","series-title":"PLoS Negl Trop Dis","first-page":"e0003919","article-title":"Taenia solium human cysticercosis: a systematic review of sero-epidemiological data from endemic zones around the world","volume":"9","author":"Coral-Almeida","year":"2015"},{"key":"b11","series-title":"Vet Parasitol","first-page":"14","article-title":"Taenia solium taeniosis\/cysticercosis in Africa: risk factors, epidemiology and prospects for control using vaccination","volume":"195","author":"Assana","year":"2013"},{"key":"b12","series-title":"PLoS Negl Trop Dis","first-page":"e0005130","article-title":"High prevalence of asymptomatic neurocysticercosis in an endemic rural community in Peru","volume":"10","author":"Moyano","year":"2016"},{"key":"b13","series-title":"Trop Med Int Health","first-page":"546","article-title":"Seizures, cysticercosis and rural-to-urban migration: the PERU MIGRANT study","volume":"20","author":"Gonzales","year":"2015"},{"key":"b14","series-title":"J Infect Dev Ctries","first-page":"799","article-title":"Seroprevalence of human cysticercosis and its associated risk factors among humans in areas of Kaduna metropolis, Nigeria","volume":"9","author":"Edia-Asuke","year":"2015"},{"key":"b15","series-title":"Am J Trop Med Hyg","first-page":"413","article-title":"Infection with versus exposure to Taenia solium: what do serological test results tell us?","volume":"83","author":"Praet","year":"2010"},{"key":"b16","series-title":"Am J Trop Med Hyg","first-page":"31","article-title":"Short report: transient antibody response in Taenia solium infection in field conditions\u2014a major contributor to high seroprevalence","volume":"65","author":"Garcia","year":"2001"},{"key":"b17","series-title":"PLoS Negl Trop Dis","first-page":"e2142","article-title":"The incidence of human cysticercosis in a rural community of eastern Zambia","volume":"7","author":"Mwape","year":"2013"},{"key":"b18","series-title":"PLoS Negl Trop Dis","first-page":"e2887","article-title":"Incidence of human Taenia solium larval infections in an Ecuadorian endemic area: implications for disease burden assessment and control","volume":"8","author":"Coral-Almeida","year":"2014"},{"key":"b19","series-title":"Lancet Glob Health","first-page":"e411","article-title":"Effectiveness of a community-based educational programme in reducing the cumulative incidence and prevalence of human Taenia solium cysticercosis in Burkina Faso in 2011\u201314 (EFECAB): a cluster-randomised controlled trial","volume":"6","author":"Carabin","year":"2018"},{"key":"b20","series-title":"Infect Dis Poverty","first-page":"95","article-title":"Development of a health education intervention strategy using an implementation research method to control taeniasis and cysticercosis in Burkina Faso","volume":"6","author":"Ngowi","year":"2017"},{"key":"b21","series-title":"Int J Parasitol","first-page":"569","article-title":"A Bayesian approach for estimating values for prevalence and diagnostic test characteristics of porcine cysticercosis","volume":"34","author":"Dorny","year":"2004"},{"key":"b22","series-title":"Trends Parasitol","first-page":"259","article-title":"Immunodiagnostic approaches for detecting Taenia solium","volume":"20","author":"Dorny","year":"2004"},{"key":"b23","author":"R Core Team","year":"2018"},{"key":"b24","series-title":"Trans R Soc Trop Med Hyg","first-page":"1241","article-title":"Prevalence and associated risk factors of Taenia solium taeniasis in a rural pig farming community of north India","volume":"101","author":"Prasad","year":"2007"},{"key":"b25","series-title":"PLoS Negl Trop Dis","first-page":"e927","article-title":"Factors associated with the prevalence of circulating antigens to porcine cysticercosis in three villages of Burkina Faso","volume":"5","author":"Ganaba","year":"2011"},{"key":"b26","series-title":"Curr Trop Med Rep","first-page":"181","article-title":"Taenia solium taeniasis and cysticercosis control and elimination through community-based interventions","volume":"1","author":"Carabin","year":"2014"},{"key":"b27","series-title":"Trop Parasitol","first-page":"100","article-title":"Human cysticercosis (Taenia solium)","volume":"3","author":"Del Brutto","year":"2013"},{"key":"b28","series-title":"Parasitol Res","first-page":"412","article-title":"Epidemiology, clinical manifestations and diagnosis of zoonotic cestode infections: an update","volume":"91","author":"Raether","year":"2003"},{"key":"b29","author":"Murrell","year":"2005"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/99\/4\/article-p1018.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/99\/4\/article-p1018.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/99\/4\/article-p1018.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T19:59:51Z","timestamp":1722455991000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/99\/4\/article-p1018.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,3]]},"references-count":29,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.18-0294","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,3]]}}}