{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T15:22:40Z","timestamp":1770909760016,"version":"3.50.1"},"reference-count":30,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,11,7]]},"abstract":"<jats:p><jats:italic>Fasciola hepatica<\/jats:italic> is the most widely distributed trematode-affecting humans. The Andes Mountains are highly endemic for fascioliasis. We report results of a cross-sectional study evaluating the epidemiology of Fasciola among children in 26 agricultural communities in the Cusco region of Peru. Children 3 to 16 years old were enrolled in preschools and schools. Blood from participants was tested for complete blood counts, transaminases, and Fasciola antibodies. Stool samples were tested for Fasciola and other parasites. A total of 2,515 children were included in the analysis and the mean age was 9.6 years (\u00b13.6). Ten percent (253) of the children had at least one positive test for Fasciola, 6% had chronic infection, and 0.4% acute infection. The rest of the subjects had only antibodies against Fasciola. The prevalence of infection varied from 0% to 20% between communities. Children with evidence of Fasciola exposure were older, lived at higher altitudes, and had a lower socioeconomic status than children without infection. The logistic regression analysis showed that children from Ancahuasi district, older children, and children with higher measures of poverty were more likely to have Fasciola exposure. Fascioliasis is common in the Cusco region and associated with poverty. However, the distribution varies markedly between communities.<\/jats:p>","DOI":"10.4269\/ajtmh.18-0372","type":"journal-article","created":{"date-parts":[[2018,9,18]],"date-time":"2018-09-18T07:01:00Z","timestamp":1537254060000},"page":"1180-1185","source":"Crossref","is-referenced-by-count":23,"title":["Socioeconomic Factors Associated with Fasciola hepatica Infection Among Children from 26 Communities of the Cusco Region of Peru"],"prefix":"10.4269","volume":"99","author":[{"given":"Miguel M.","family":"Cabada","sequence":"first","affiliation":[{"name":"Infectious Diseases Division, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas;"},{"name":"Alexander von Humboldt Tropical Medicine Institute, Department of Medicine, Universidad Peruana Cayetano Heredia, Cusco Branch, Peru;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Luisa","family":"Morales","sequence":"additional","affiliation":[{"name":"Alexander von Humboldt Tropical Medicine Institute, Department of Medicine, Universidad Peruana Cayetano Heredia, Cusco Branch, Peru;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camille M.","family":"Webb","sequence":"additional","affiliation":[{"name":"Infectious Diseases Division, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Logan","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Medicine, University of Texas Medical Branch, Galveston, Texas;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chelsey A.","family":"Bravenec","sequence":"additional","affiliation":[{"name":"School of Medicine, University of Texas Medical Branch, Galveston, Texas;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha","family":"Lopez","sequence":"additional","affiliation":[{"name":"Alexander von Humboldt Tropical Medicine Institute, Department of Medicine, Universidad Peruana Cayetano Heredia, Cusco Branch, Peru;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruben","family":"Bascope","sequence":"additional","affiliation":[{"name":"Zoonosis Unit, Direccion Regional de Salud del Cusco, Ministerio de Salud, Cusco, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. Clinton","family":"White","sequence":"additional","affiliation":[{"name":"Infectious Diseases Division, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Gotuzzo","sequence":"additional","affiliation":[{"name":"Alexander von Humboldt Tropical Medicine Institute, Department of Medicine, Universidad Peruana Cayetano Heredia, Cusco Branch, Peru;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","author":"WHO","year":"2017"},{"key":"b2","series-title":"Exp Parasitol","first-page":"81","article-title":"Controversial aspects of the life cycle of Fasciola hepatica","volume":"169","author":"Moazeni","year":"2016"},{"key":"b3","series-title":"Curr Opin Infect Dis","first-page":"518","article-title":"New developments in epidemiology, diagnosis, and treatment of 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