{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T05:43:21Z","timestamp":1793684601069,"version":"4.5.1"},"reference-count":32,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,2,6]]},"abstract":"<jats:p>Jamestown Canyon virus (JCV), a mosquito-borne <jats:italic>Orthobunyavirus<\/jats:italic> (within the California serogroup), can cause severe neuroinvasive disease. According to national data during 2000\u20132013, 42% of the 31 documented JCV disease cases in the United States were detected in residents from Wisconsin. The Wisconsin Division of Public Health enhanced JCV surveillance by implementing routine use of JCV-specific immunoglobulin M (IgM) antibody testing followed by confirmatory JCV-specific plaque reduction neutralization testing on all patients with suspected cases of arboviral infection who had tests positive for arboviral immunoglobin at commercial laboratories. During 2011\u20132016, of the 287 Wisconsin specimens tested on the Arbovirus IgM Antibody Panel, 30 JCV cases were identified (26 confirmed and four probable). Twenty-seven (90%) JCV cases were detected after 2013. Among all cases, 17 (56%) were male and the median age was 54 years (range: 10\u201384 years). Fifteen patients had neuroinvasive disease, including meningitis (<jats:italic>n<\/jats:italic> = 9) and meningoencephalitis (<jats:italic>n<\/jats:italic> = 6). Although historically considered rare, the relatively high rate (0.12 cases\/100,000 population) of diagnosis of JCV infections among Wisconsin residents during 2013\u20132016 compared with that in previous years suggests occurrence is widespread throughout Wisconsin and historically may have been under-recognized. This study aims to raise awareness of JCV infection for differential diagnosis among the arboviral diseases. Improved and timely diagnosis of arboviral disease is important in that it will provide more information regarding emerging infections and promote preventive measures to avoid mosquito-borne exposure and infection among residents of and visitors to affected areas.<\/jats:p>","DOI":"10.4269\/ajtmh.18-0575","type":"journal-article","created":{"date-parts":[[2018,12,11]],"date-time":"2018-12-11T07:01:05Z","timestamp":1544511665000},"page":"445-451","source":"Crossref","is-referenced-by-count":29,"title":["Enhanced Arboviral Surveillance to Increase Detection of Jamestown Canyon Virus Infections, Wisconsin, 2011\u20132016"],"prefix":"10.4269","volume":"100","author":[{"given":"Eduard","family":"Matkovic","sequence":"first","affiliation":[{"name":"Division of Public Health, Wisconsin Department of Health Services, Madison, Wisconsin;"},{"name":"Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diep K.","family":"Hoang Johnson","sequence":"additional","affiliation":[{"name":"Division of Public Health, Wisconsin Department of Health Services, Madison, Wisconsin;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Erin","family":"Staples","sequence":"additional","affiliation":[{"name":"Arboviral Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria C.","family":"Mora-Pinzon","sequence":"additional","affiliation":[{"name":"Division of Public Health, Wisconsin Department of Health Services, Madison, Wisconsin;"},{"name":"Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina I.","family":"Elbadawi","sequence":"additional","affiliation":[{"name":"Division of Public Health, Wisconsin Department of Health Services, Madison, Wisconsin;"},{"name":"Career Epidemiology Field Officer, Office of Public Health Preparedness and Response, Centers for Disease Control and Prevention, Atlanta, Georgia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca A.","family":"Osborn","sequence":"additional","affiliation":[{"name":"Division of Public Health, Wisconsin Department of Health Services, Madison, Wisconsin;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M.","family":"Warshauer","sequence":"additional","affiliation":[{"name":"Wisconsin State Laboratory of Hygiene, Madison, Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark V.","family":"Wegner","sequence":"additional","affiliation":[{"name":"Division of Public Health, Wisconsin Department of Health Services, Madison, Wisconsin;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey P.","family":"Davis","sequence":"additional","affiliation":[{"name":"Division of Public Health, Wisconsin Department of Health Services, Madison, Wisconsin;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Prog Clin Biol Res","first-page":"1","article-title":"Taxonomy, classification, and geographic distribution of California serogroup bunyaviruses","volume":"123","author":"Calisher","year":"1983"},{"key":"b2","series-title":"Am J Trop Med Hyg","first-page":"384","article-title":"Jamestown Canyon virus disease in the United States-2000\u20132013","volume":"93","author":"Pastula","year":"2015"},{"key":"b3","series-title":"J Med Entomol","first-page":"588","article-title":"An ecological study of Jamestown Canyon virus on the Delmarva Peninsula, with emphasis on its possible vector","volume":"23","author":"Clark","year":"1986"},{"key":"b4","series-title":"J Med Entomol","first-page":"1053","article-title":"Isolations of Jamestown Canyon virus (Bunyaviridae: California serogroup) from mosquitoes (Diptera: Culicidae) in the western United States, 1990\u20131992","volume":"30","author":"Hardy","year":"1993"},{"key":"b5","series-title":"J Med Entomol","first-page":"257","article-title":"Arbovirus surveillance in northern Colorado, 1987 and 1991","volume":"30","author":"Smith","year":"1993"},{"key":"b6","series-title":"J Am Mosq Control Assoc","first-page":"131","article-title":"Isolation of Jamestown canyon and snowshoe hare viruses (California serogroup) from Aedes mosquitoes in western Massachusetts","volume":"9","author":"Walker","year":"1993"},{"key":"b7","author":"Centers for Disease Control and Prevention CDC Arboviral Catalog","year":"2016"},{"key":"b8","series-title":"Am J Trop Med Hyg","first-page":"440","article-title":"Isolation of Jamestown canyon serotype of California encephalitis virus from naturally infected Aedes mosquitoes and tabanids","volume":"18","author":"DeFoliart","year":"1969"},{"key":"b9","series-title":"Am J Epidemiol","first-page":"230","article-title":"California encephalitis virus studies in Wisconsin","volume":"81","author":"Thompson","year":"1965"},{"key":"b10","series-title":"Am J Trop Med Hyg","first-page":"1238","article-title":"A case of encephalitis in a human associated with a serologic rise to Jamestown Canyon virus","volume":"31","author":"Grimstad","year":"1982"},{"key":"b11","series-title":"Am J Trop Med Hyg","first-page":"1218","article-title":"Claifornia serogroup viruses in New York state: the role of subtypes in human infections","volume":"33","author":"Srihongse","year":"1984"},{"key":"b12","series-title":"Encyclopedia of Arthropod- Transmitted Infections of Man and Domestic Animals","first-page":"235","article-title":"Jamestown Canyon virus","author":"Grimstad","year":"2001"},{"key":"b13","series-title":"J Clin Microbiol","first-page":"503","article-title":"Serum dilution neutralization test for California group virus identification and serology","volume":"4","author":"Lindsey","year":"1976"},{"key":"b14","series-title":"J immunol","first-page":"291","article-title":"Dengue virus identification by the plaque reduction neutralization test","volume":"99","author":"Russell","year":"1967"},{"key":"b15","series-title":"J immunol","first-page":"285","article-title":"A plaque reduction test for dengue virus neutralizing antibodies","volume":"99","author":"Russell","year":"1967"},{"key":"b16","series-title":"Vector Borne Zoonotic Dis","first-page":"191","article-title":"Serological survey for antibodies to mosquito-borne bunyaviruses among US National Park service and US forest service employees","volume":"16","author":"Kosoy","year":"2016"},{"key":"b17","series-title":"Virology","first-page":"201","article-title":"Full genomic characterization of California serogroup viruses, genus orthobunyavirus, family peribunyaviridae including phylogenetic relationships","volume":"512","author":"Hughes","year":"2017"},{"key":"b18","series-title":"J Clin Microbiol","first-page":"1823","article-title":"Standardization of immunoglobulin M capture enzyme-linked immunosorbent assay for routine diagnosis of arboviral infections","volume":"38","author":"Martin","year":"2000"},{"key":"b19","author":"Wisconsin Department of Health Services","year":"2016"},{"key":"b20","author":"Centers for Disease Control and Prevention","year":"2011"},{"key":"b21","author":"Wisconsin Interactive Statistics on Health","year":"2016"},{"key":"b22","series-title":"WMJ","first-page":"185","article-title":"Endemic human mosquito-borne disease in Wisconsin residents, 2002\u20132006","volume":"106","author":"Sotir","year":"2007"},{"key":"b23","author":"United States Geological Survey","year":"2017"},{"key":"b24","series-title":"Emerg Infect Dis","first-page":"911","article-title":"Jamestown Canyon virus: seroprevalence in Connecticut","volume":"7","author":"Mayo","year":"2001"},{"key":"b25","series-title":"Pediatrics","first-page":"642","article-title":"Neuroinvasive arboviral disease in the United States: 2003 to 2012","volume":"134","author":"Gaensbauer","year":"2014"},{"key":"b26","series-title":"Feigin and Cherry\u2019s Textbook of Pediatric Infectious Diseases","first-page":"2513","article-title":"La Crosse encephalitis and other California serogroup viruses","author":"Hunt","year":"2014"},{"key":"b27","series-title":"MMWR Morb Mortal Wkly Rep","first-page":"521","article-title":"West Nile virus and other arboviral diseases\u2013United States, 2013","volume":"63","author":"Lindsey","year":"2014"},{"key":"b28","series-title":"The Arboviruses: Epidemiology and Ecology","first-page":"99","article-title":"California group virus disease","author":"Grimstad","year":"1988"},{"key":"b29","doi-asserted-by":"crossref","DOI":"10.1016\/B978-012370466-5.50010-8","article-title":"Suburbanization in developed nations","author":"Falco","year":"2008"},{"key":"b30","series-title":"Am J Trop Med Hyg","first-page":"985","article-title":"Serologic evidence of infections of white-tailed deer in Wisconsin with three California group arboviruses (La Crosse, Trivittatus, and Jamestown Canyon)","volume":"21","author":"Issel","year":"1972"},{"key":"b31","series-title":"Vector Borne Zoonotic Dis","first-page":"75","article-title":"Isolations of Jamestown Canyon virus (Bunyaviridae: Orthobunyavirus) from field-collected mosquitoes (Diptera: Culicidae) in Connecticut, USA: a ten-Year analysis, 1997\u20132007","volume":"8","author":"Andreadis","year":"2008"},{"key":"b32","series-title":"Am J Trop Med Hyg","first-page":"1157","article-title":"Genetic relationships of Jamestown Canyon virus strains infecting mosquitoes collected in Connecticut","volume":"77","author":"Armstrong","year":"2007"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/100\/2\/article-p445.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/100\/2\/article-p445.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/100\/2\/article-p445.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T14:11:19Z","timestamp":1722435079000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/100\/2\/article-p445.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,6]]},"references-count":32,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.18-0575","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,6]]}}}