{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:23:57Z","timestamp":1761578637228},"reference-count":13,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,1,9]]},"abstract":"<jats:p>In high prevalence settings, cryptosporidiosis is commonly implicated as a cause of a gastroenteritis syndrome in the organ transplant population. Stool microscopy is predominant diagnostic modality. Therapeutic options in this group of patients are limited, making their management exceptionally challenging. We describe a case of a renal transplant recipient with cryptosporidiosis confirmed by the stool FilmArray gastrointestinal panel (GIP) nucleic acid-based assay and stool microscopy, describe our institutional experience in diagnosing cryptosporidiosis in a low-prevalence setting, and review the available literature on management of this condition in the organ transplant population. In a low-prevalence setting, the GIP can serve as a rapid screening tool in the diagnosis of cryptosporidiosis.<\/jats:p>","DOI":"10.4269\/ajtmh.18-0651","type":"journal-article","created":{"date-parts":[[2018,11,20]],"date-time":"2018-11-20T07:18:13Z","timestamp":1542698293000},"page":"78-80","source":"Crossref","is-referenced-by-count":7,"title":["Case Report: Diagnosis of Cryptosporidiosis in Renal Transplantation in a Low-Prevalence Setting"],"prefix":"10.4269","volume":"100","author":[{"given":"Shuwei","family":"Zheng","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Singapore General Hospital, Singapore;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwan Ki Karrie","family":"Ko","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Singapore General Hospital, Singapore;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kian Sing","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Molecular Pathology, Singapore General Hospital, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Indumathi","family":"Venkatachalam","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Singapore General Hospital, Singapore;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"World J Transplant","first-page":"460","article-title":"Cryptosporidium infection in solid organ transplantation","volume":"6","author":"Florescu","year":"2016"},{"key":"b2","series-title":"Int J Hyg Environ Health","first-page":"1098","article-title":"Cryptosporidium and cryptosporidiosis: the Asian perspective","volume":"220","author":"Mahmoudi","year":"2017"},{"key":"b3","series-title":"PLoS Med","first-page":"e1001920","article-title":"World Health Organization estimates of the global and regional disease burden of 11 foodborne parasitic diseases, 2010: a data synthesis","volume":"12","author":"Torgerson","year":"2015"},{"key":"b4","series-title":"Clin Microbiol Infect","first-page":"190.e1","article-title":"Is real-time PCR-based diagnosis similar in performance to routine parasitological examination for the identification of Giardia intestinalis, Cryptosporidium parvum\/Cryptosporidium hominis and Entamoeba histolytica from stool samples? Evaluation of a new commercial multiplex PCR assay and literature review","volume":"22","author":"Laude","year":"2016"},{"key":"b5","series-title":"PLoS One","first-page":"e0173196","article-title":"Agreement between gastrointestinal panel testing and standard microbiology methods for detecting pathogens in suspected infectious gastroenteritis: test evaluation and meta-analysis in the absence of a reference standard","volume":"12","author":"Freeman","year":"2017"},{"author":"BIOMERIEUX","key":"b6"},{"key":"b7","series-title":"J Clin Microbiol","first-page":"915","article-title":"Multicenter evaluation of the BioFire FilmArray gastrointestinal panel for etiologic diagnosis of infectious gastroenteritis","volume":"53","author":"Buss","year":"2015"},{"key":"b8","series-title":"Transpl Infect Dis","first-page":"48","article-title":"Cryptosporidium infection after renal transplantation in an endemic area","volume":"17","author":"Bhadauria","year":"2015"},{"key":"b9","series-title":"J Infect Dis","first-page":"559","article-title":"Cryptosporidium infection in renal transplant patients","volume":"160","author":"Roncoroni","year":"1989"},{"key":"b10","series-title":"J Nephropathol","first-page":"127","article-title":"Prevalence of cryptosporidiosis in renal transplant recipients presenting with acute diarrhea at a single center in Pakistan","volume":"3","author":"Raja","year":"2014"},{"key":"b11","series-title":"Transplantation","first-page":"826","article-title":"Cryptosporidium spp. infection in solid organ transplantation: the nationwide \u201cTRANSCRYPTO\u201d study","volume":"101","author":"Lanternier","year":"2017"},{"key":"b12","series-title":"Aliment Pharmacol Ther","first-page":"887","article-title":"Nitazoxanide in the treatment of acquired immune deficiency syndrome-related cryptosporidiosis: results of the United States compassionate use program in 365 patients","volume":"24","author":"Rossignol","year":"2006"},{"key":"b13","series-title":"J Infect Dis","first-page":"900","article-title":"Combination drug therapy for cryptosporidiosis in AIDS","volume":"178","author":"Smith","year":"1998"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/100\/1\/article-p78.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/100\/1\/article-p78.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/100\/1\/article-p78.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T11:24:33Z","timestamp":1722425073000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/100\/1\/article-p78.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,9]]},"references-count":13,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.18-0651","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"type":"print","value":"0002-9637"},{"type":"electronic","value":"1476-1645"}],"subject":[],"published":{"date-parts":[[2019,1,9]]}}}