{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T21:04:48Z","timestamp":1773867888470,"version":"3.50.1"},"reference-count":43,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,12,4]]},"abstract":"<jats:p>Leptospirosis is a zoonotic bacterial disease caused by pathogenic species of the genus <jats:italic>Leptospira<\/jats:italic>. Disease incidence is known to be attributed to environmental and social conditions which promote the spread of reservoir hosts, primarily rodents. A well-being program was conducted to determine the seroprevalence and risk factors associated with leptospirosis in urban poor communities occupying low-cost flat accommodation and squatter settlements in the vicinity of Wilayah Persekutuan, Kuala Lumpur. Blood samples from a total of 532 volunteers were screened for the detection of IgG and IgM antibodies against leptospirosis using ELISA. Demographic data were collected for each participant through a questionnaire survey before blood collection. The overall seroprevalence was low (12.6%, <jats:italic>n<\/jats:italic> = 67\/532; 95% CI: 9.9\u201315.7%), with 8.1% (<jats:italic>n<\/jats:italic> = 43\/532) being seropositive for anti-<jats:italic>Leptospira<\/jats:italic> IgG, indicating previous infection, and 4.9% (<jats:italic>n<\/jats:italic> = 26\/532) for anti-<jats:italic>Leptospira<\/jats:italic> IgM, indicating current infection. Two significant factors such as host age (<jats:italic>P \u2264<\/jats:italic> 0.01) and knowledge of disease transmission (<jats:italic>P<\/jats:italic> = 0.017) significantly influenced the presence of anti-<jats:italic>Leptospira<\/jats:italic> IgM, whereas the detection of anti-IgG indicated the presence of clean drinking water sources (<jats:italic>P<\/jats:italic> = 0.043). Despite the low prevalence, the transmission of leptospirosis does occur among urban poor communities, suggesting the need for undertaking public awareness programs.<\/jats:p>","DOI":"10.4269\/ajtmh.19-0003","type":"journal-article","created":{"date-parts":[[2019,10,15]],"date-time":"2019-10-15T07:00:29Z","timestamp":1571122829000},"page":"1265-1271","source":"Crossref","is-referenced-by-count":10,"title":["Seroprevalence of Anti-Leptospira IgG and IgM Antibodies and Risk Assessment of Leptospirosis among Urban Poor Communities in Kuala Lumpur, Malaysia"],"prefix":"10.4269","volume":"101","author":[{"given":"Norhidayu","family":"Sahimin","sequence":"first","affiliation":[{"name":"Tropical Infectious Diseases Research and Education Centre (TIDREC), University of Malaya, Kuala Lumpur, Malaysia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siti Aishah","family":"Sharif","sequence":"additional","affiliation":[{"name":"Faculty of Science, Institute of Biological Sciences, University of Malaya, Kuala Lumpur, Malaysia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Izzah Ruzana","family":"Mohd Hanapi","sequence":"additional","affiliation":[{"name":"Faculty of Science, Institute of Biological Sciences, University of Malaya, Kuala Lumpur, Malaysia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sukchinda","family":"Nai Chuan","sequence":"additional","affiliation":[{"name":"Faculty of Science, Institute of Biological Sciences, University of Malaya, Kuala Lumpur, Malaysia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John W.","family":"Lewis","sequence":"additional","affiliation":[{"name":"School of Biological Sciences, Royal Holloway, University of London, Egham, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benacer","family":"Douadi","sequence":"additional","affiliation":[{"name":"Faculty of Science, Institute of Biological Sciences, University of Malaya, Kuala Lumpur, Malaysia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siti Nursheena","family":"Mohd Zain","sequence":"additional","affiliation":[{"name":"Faculty of Science, Institute of Biological Sciences, University of Malaya, Kuala Lumpur, Malaysia;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"J Appl Sci","first-page":"154","article-title":"Urbanization and urban poverty in Malaysia: consequences and vulnerability","volume":"16","author":"Siwar","year":"2016"},{"key":"b2","series-title":"Procedia Soc Behav Sci","first-page":"827","article-title":"Housing conditions and quality of life of the urban poor in Malaysia","volume":"50","author":"Zainal","year":"2012"},{"key":"b3","series-title":"Br J Ind Med","first-page":"721","article-title":"Leptospirosis as an occupational disease","volume":"43","author":"Waitkins","year":"1986"},{"key":"b4","series-title":"Int J Syst Evol 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